Alkynyl phenyl derivative compounds for treating ophthalmic diseases and disorders

Inventors: Ian Leslie Scott (Monroe, WA); Vladimir Aleksandrovich Kuksa (Bothell, WA); Mark W. Orme (Seattle, WA); Thomas Little (Redmond, WA); Anna Gall (Woodinville, WA); Jennifer Gage (Kenmore, WA); Feng Hong (Bellevue, WA)

Assignee: ACUCELA INC.

C07C215/68 C07C211/27 C07C211/30 C07C215/28 C07C215/30 C07C215/42 C07C217/14 C07C217/48 C07C217/62 C07C217/64 C07C217/72 C07C235/34 C07C237/20 C07C251/40 C07C255/58 C07C317/28 C07C323/25 C07C323/29 C07C323/36 C07D209/32 C07D213/14 C07D213/38 C07D309/06 C07D309/10 C07D309/12 C07D333/06 C07D333/16 C07D335/02 C07C2101/02 C07C2101/04 C07C2101/08 C07C2101/14 C07C2101/18

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Quick Facts

Patent No.: US 9,464,033
App. No.: 14/807,436
Granted: Oct 11, 2016
Kind: B2

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Abstract

Provided are alkynyl phenyl derivative compounds, pharmaceutical compositions thereof, and methods of treating ophthalmic diseases and disorders, such as age-related macular degeneration and Stargardt's Disease, using said compounds and compositions.

Claims (2)

1. A compound, or a pharmaceutically acceptable salt thereof, selected from:

2. A pharmaceutical composition comprising a compound of claim 1 , or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable excipient.

Assignments (1)

ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 14, 2015

From: SCOTT, IAN LESLIE; KUKSA, VLADIMIR ALEKSANDROVICH; ORME, MARK W.; LITTLE, THOMAS; GALL, ANNA; GAGE, JENNIFER; HONG, FENG

To: ACUCELA INC.

Reel/Frame 036560/0809 →

Continuity (6)

Continuation 14523777 · Oct 24, 2014

Division 14162672 · Jan 23, 2014

Division 13619948 · Sep 14, 2012

Continuation 12217022 · Jun 30, 2008

Provisional Application 60947321 · Jun 29, 2007

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