IP Library Granted Patent US 9,884,191
Granted Patent B2
US 9,884,191 · App. 14/811,171 · Granted Feb 6, 2018

Apparatus, system, and method for selective stimulation

Inventors: Paul M. Meadows (Glendale, CA); Marcelo G. Lima (San Diego, CA); Stanley R. Craig (Westport, MA)
Assignee: ImThera Medical, Inc.
A61N1/3611A61N1/0556A61N1/3605A61N1/375A61N1/378A61N1/36071A61N1/36135A61N1/3758
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Quick Facts
Patent No.
US 9,884,191
App. No.
14/811,171
Granted
Feb 6, 2018
Kind
B2
Abstract

An implantable neurostimulator system is disclosed, the neurostimulator system comprising a hollow cylindrical electronics enclosure having a top, a bottom, and a side; a coil extending from a first part of the electronics enclosure; and at least one electrode operatively connected to the electronics enclosure.

Claims (17)

1. A method of treating sleep apnea using neurostimulation to control the position of a patient's tongue, comprising the steps of:

implanting a first electrode having at least one first contact into a patient to electrically couple the at least one first contact to a first Hypoglossal nerve of the patient;

implanting a second electrode having at least one second contact into a patient to electrically couple the at least one second contact to a second Hypoglossal nerve of the patient;

implanting an implantable pulse generator (IPG) into the patient, the IPG being electronically coupled to the first electrode and the second electrode;

programming the IPG to deliver electric signals to the at least one first contact and the at least one second contact during a therapy session; and

applying the electric signals via the at least one first contact and the at least one second contact to the first and second Hypoglossal nerves respectively to stimulate a portion of the first Hypoglossal nerve and a portion of the second Hypoglossal nerve to treat sleep apnea by preventing the tongue from blocking an airway during the therapy session,

wherein applying the electric signals includes driving each of the at least one first contact and the at least one second contact by their own independent current source.

2. The method of claim 1 , wherein the first electrode and the second electrode each include a cuff housing and wherein implanting the first electrode includes wrapping the cuff housing of the first electrode around a portion of the first Hypoglossal nerve and implanting the second electrode includes wrapping the cuff housing of the second electrode around a portion of the second Hypoglossal nerve.

3. The method of claim 2 , wherein implanting the first electrode includes wrapping the cuff housing of the first electrode around the portion of the first Hypoglossal nerve at least once and implanting the second electrode includes wrapping the cuff housing of the second electrode around the portion of the second Hypoglossal nerve at least once.

4. The method of claim 1 , wherein the electric signals are applied approximately simultaneously.

5. The method of claim 1 , wherein the electric signals are applied sequentially.

6. The method of claim 1 , wherein the electric signals are applied to the first and second Hypoglossal nerves such that the stimulation of one of the at least two muscles of the tongue partially overlaps with the stimulation of another of the at least two muscles of the tongue.

7. The method of claim 1 , wherein at least one of the electric signals is an asymmetric pulse.

8. The method of claim 1 , wherein each of the electric signals is a pulse train having a frequency between approximately 1 and approximately 100 Hertz.

9. The method of claim 1 , wherein the electric signals are applied to the first and second Hypoglossal nerves via an open loop system.

10. The method of claim 1 , wherein the IPG is programmed without taking into account a timing of respiration.

11. The method of claim 1 , wherein the IPG is implanted in the sub-mandibular space of the patient.

Assignments (6)
RELEASE OF SECURITY INTEREST Recorded Sep 20, 2021
From: ACF FINCO I LP
To: IMTHERA MEDICAL, INC.
Reel/Frame 057535/0850 →
SECURITY INTEREST Recorded Aug 16, 2021
From: IMTHERA MEDICAL, INC.
To: GOLDMAN SACHS BANK USA, AS COLLATERAL AGENT
Reel/Frame 057188/0115 →
RELEASE OF SECURITY INTEREST Recorded Aug 16, 2021
From: ARES CAPITAL CORPORATION, AS AGENT FOR THE LENDERS
To: IMTHERA MEDICAL, INC.
Reel/Frame 057188/0573 →
PATENT SECURITY AGREEMENT Recorded Dec 30, 2020
From: IMTHERA MEDICAL, INC.
To: ACF FINCO I LP, AS COLLATERAL AGENT
Reel/Frame 054881/0683 →
PATENT SECURITY AGREEMENT Recorded Jun 17, 2020
From: IMTHERA MEDICAL, INC.
To: ARES CAPITAL CORPORATION, AS COLLATERAL AGENT
Reel/Frame 052963/0651 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 29, 2015
From: MEADOWS, PAUL M; LIMA, MARCELO G; CRAIG, STANLEY R
To: IMTHERA MEDICAL, INC
Reel/Frame 036203/0968 →
Continuity (6)
Continuation 13775349 · Feb 25, 2013
Continuation 12681812
Provisional Application 61136102 · Aug 12, 2008
Provisional Application 61017614 · Dec 29, 2007
Provisional Application 60978519 · Oct 9, 2007
Related Publication 20150328455A1 · Nov 19, 2015