IP Library Granted Patent US 9,861,293
Granted Patent B2
US 9,861,293 · App. 14/826,134 · Granted Jan 9, 2018

Sensors, including disposable sensors, for measuring tissue

Inventors: Elmer C. Lupton (Charlestown, MA); Haydn Taylor (Windham, NH); Jose Bohorquez (San Francisco, CA); Ken Li (Wellesley, MA); Michael Rinehart (San Jose, CA)
Assignee: Myolex Inc.
A61B5/053A61B5/4519A61B5/486A61B5/684A61B5/6843A61B5/7221A61B5/7225A61B5/7278A61B5/742A61B5/7405A61B5/7475A61B5/6833A61B2017/0023A61B2560/0412A61B2560/0443A61B2560/0468A61B2562/04A61B2562/046A61B2562/14A61B2562/164A61B2562/166
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Quick Facts
Patent No.
US 9,861,293
App. No.
14/826,134
Granted
Jan 9, 2018
Kind
B2
Abstract

Embodiments of devices and methods for evaluating tissue are disclosed. In one embodiment, a method for measuring a characteristic of a tissue may include passing a current through the tissue, measuring a signal corresponding to the voltage resulting from passing the current through the tissue, analyzing current passed through the tissue and resulting voltage to determine the electrical characteristics of the tissue; and analyzing the electrical characteristics of the tissue to determine a status of the tissue. Disposable sensors are disclosed.

Claims (27)

1. A method for measuring a localized biological transfer impedance (LBTI) of a tissue, using a device including a disposable sensor with a plurality of electrodes, the plurality of electrodes including at least a pair of current electrodes and a pair of voltage electrodes, with one or more of the plurality of electrodes comprising one or more sensor pads, the method comprising:

positioning the plurality of electrodes of the device in contact with a portion of the tissue so that at least one sensor pad is in contact with the portion of tissue;

passing a current through the tissue using the pair of current electrodes so that the current also passes through the at least one sensor pad which is in contact with the portion of tissue;

measuring a signal across the pair of voltage electrodes, the signal corresponding to a voltage resulting from the current passed through the tissue;

and analyzing the current passed through the tissue and the measured signal to determine the localized biological transfer impedance (LBTI) of the tissue.

2. The method of claim 1 , in which at least one of the one or more sensor pads comprises a hydrophilic coating.

3. The method of claim 2 , in which the hydrophilic coating on at least one of the sensor pads comprises one or more gel blocks.

4. The method of claim 2 , in which the hydrophilic coating on at least one of the sensor pads is prewetted during the assembly process of the device.

5. The method of claim 2 in which the hydrophilic coating on at least one of the sensor pads is moistened immediately prior to use.

6. The method of claim 3 in which the gel block comprises an ionic gel.

7. The method of claim 3 in which the gel block comprises a non-ionic gel.

8. A device for measuring

the localized biological transfer impedance (LBTI) of a tissue comprising:

a disposable sensor with a plurality of electrodes, the plurality of electrodes including at least a pair of current electrodes and a pair of voltage electrodes, with one or more of the plurality of electrodes comprising one or more sensor pads,

a power supply configured to be operably coupled to the plurality of electrodes to supply a signal through the tissue;

analytical electronics configured to be operably coupled to the plurality of electrodes for analyzing a input current and resulting voltage to determine the electrical characteristics of the tissue; and

electronics configured to communicate to a user a result of analysis performed by the analytical electronics.

9. The device of claim 8 in which at least one of the one or more sensor pads comprises a hydrophilic coating.

10. The device of claim 9 in which the hydrophilic coating on at least one of the sensor pads comprises one or more gel blocks.

11. The device of claim 9 in which the hydrophilic coating on at least one of the sensor pads is prewetted during the assembly process of the device.

12. The device of claim 9 in which the hydrophilic coating on at least one of the sensor pads is moistened immediately prior to use.

13. The device of claim 10 in which the gel block comprises an ionic gel.

14. The device of claim 10 in which the gel block comprises a non-ionic gel.

15. The method of claim 3 in which at least one gel block is prewetted during the assembly process of the device.

16. The method of claim 3 in which at least one gel block is moistened immediately prior to use.

17. The device of claim 10 in which at least one gel block is prewetted during the assembly process of the device.

18. The device of claim 10 in which at least one gel block is moistened immediately prior to use.

Assignments (7)
CONFIRMATORY LICENSE Recorded Jan 30, 2024
From: SKULPT, INC.
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 066378/0805 →
CONFIRMATORY LICENSE Recorded Jan 9, 2024
From: MYOLEX, INC
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 066238/0662 →
CHANGE OF NAME Recorded Sep 26, 2017
From: SKULPT INC.
To: MYOLEX INC.
Reel/Frame 044013/0580 →
CONFIRMATORY LICENSE Recorded Mar 3, 2017
From: SKULPT, INC.
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 041886/0741 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 10, 2015
From: BOHORQUEZ, JOSE L.; RINEHART, MICHAEL; LI, KEN; TAYLOR, HAYDN; LUPTON, ELMER C.
To: CONVERGENCE MEDICAL DEVICES, INC.
Reel/Frame 037003/0263 →
CHANGE OF NAME Recorded Nov 10, 2015
From: CONVERGENCE MEDICAL DEVICES, INC.
To: SKULPT, INC.
Reel/Frame 037085/0785 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 2, 2015
From: BOHORQUEZ, JOSE; LUPTON, ELMER C; RINEHART, MICHAEL; LI, KEN; TAYLOR, HADYN
To: SKULPT INC.
Reel/Frame 036480/0361 →
Continuity (6)
Division 13842698 · Mar 15, 2013
Continuation In Part 13823659
Provisional Application 61480127 · Apr 28, 2011
Provisional Application 61570298 · Dec 13, 2011
Provisional Application 61775620 · Mar 10, 2013
Related Publication 20160038053A1 · Feb 11, 2016