Granted Patent B2

US 10,413,635 · App. 14/827,445 · Granted Sep 17, 2019

Abstract

Claims (11)

1. A transplant product derived from human umbilical cord comprising:

a collagenous tissue membrane of umbilical cord, configured as a layer of a soft tissue barrier or wound covering or other internal or external wound healing attachment; and wherein structural, chemical and biochemical properties of the collagenous tissue membrane are retained after the collagenous tissue membrane is cleaned removing veins, arteries and Wharton's jelly without exposing the collagenous tissue membrane to chemical and biochemical property altering chemicals and wherein the collagenous tissue membrane is dried and then cut into square or rectangular shapes, after drying the dried cut collagenous tissue membrane has a plurality of suture entry sites, each suture entry site formed integrally as a structurally enhanced peripheral wall that acts and performs like a grommet but without any additional parts, and wherein each of the suture entry sites is formed by a heated tip that forms a toughened tissue membrane wall encircling each of the suture entry sites wherein each of the suture entry sites is heat formed having a reduced thickness puncture center surrounded by the toughened tissue membrane wall, the toughened tissue membrane wall being rigid and thickened relative to exterior surfaces of the collagenous tissue membrane surrounding the grommet, the exterior surfaces having a thickness between 100 to 1000 microns;

wherein the cut collagenous tissue membrane has two opposite edges, adjacent each edge is at least one of the plurality of suture entry sites;

wherein a number of the plurality of the suture entry sites adjacent one edge is one less, equal to or one more than a number of the plurality of the suture entry sites of the opposite edge;

wherein the plurality of the suture entry sites of one edge are offset relative to the plurality of the suture entry sites of the opposite edge wherein the offset is arranged and positioned so the suture entry sites on one edge are interposed between the suture entry sites of the other edge when the cut collagenous tissue membrane is rolled or folded such that the two opposing edges are aligned;

wherein the plurality of the suture entry sites of each edge are configured to pass a suture through the layer of the square or rectangular shape which is rolled or folded held by the suture so the two opposing edges are aligned to form a cylindrical cut collagenous tissue membrane for wrapping about a nerve, vein, artery or any other tubular or round tissue vessel; and

wherein the transplant product has the collagenous tissue membrane dried, the dried membrane having the thickness in the range of 100 to 1000 microns.

2. The transplant product of claim 1 wherein the collagenous tissue membrane is soaked in normal saline solution under mild agitation for a predetermined time to structurally increase tear resistance of the collagenous tissue membrane.

3. The transplant product of claim 2 wherein the collagenous tissue membrane is free of meconium.

4. The transplant product of claim 3 wherein the collagenous tissue membrane has a transparent or translucent appearance of a clear or pink color.

5. The transplant product of claim 1 wherein the collagenous tissue membrane is subjected to a vacuum drying process under vacuum at a prescribed vacuum over a predetermined time at room temperature sufficient to dry without altering the structural and chemical properties of the collagenous tissue membrane.

Assignments (8)