METHOD OF TREATING ALLERGIC CONJUNCTIVITIS WITH CYCLOSPORIN COMPOSITIONS

1 . A method of treating an allergic conjunctivitis, the method comprising topically administering to an eye affected with such a condition a composition comprising cyclosporin A, at a concentration between about 0.001% (w/v) to about 0.01% (w/v), to an eye of a subject having allergic conjunctivitis.

2 . The method of 1 , wherein the allergic conjunctivitis is selected from the group consisting of seasonal allergic conjunctivitis, perennial allergic conjunctivitis, atopic keratoconjunctivitis, and vernal keratoconjunctivitis.

3 . A method of treating atopic keratoconjunctivitis, the method comprising the step of topically administering to an eye affected with such a condition a composition comprising cyclosporin A at a concentration of 0.005% (w/v) or 0.001% (w/v).

4 . The method of claim 3 , wherein the composition further comprises

Carboxymethylcellulose sodium, 0.5% (w/v),

Polysorbate 80, 1.0% (w/v),

Glycerin, 1.0% (w/v),

Mannitol, 0.5% (w/v),

Sodium citrate dihydrate, 0.4% (w/v),

Boric acid, 0.25% (w/v),

Sodium borate decahydrate, 0.41% (w/v), and

Potassium chloride 0.14% (w/v).

5 . A method of treating vernal keratoconjunctivitis, the method comprising the step of topically administering to an eye affected with such a condition to a patient having atopic keratoconjunctivitis a composition comprising cyclosporin A at a concentration of 0.005% (w/v) or 0.001% (w/v).

6 . The method of claim 5 , wherein the composition further comprises

Carboxymethylcellulose sodium, 0.5% (w/v),

Polysorbate 80, 1.0% (w/v),

Glycerin, 1.0% (w/v),

Mannitol, 0.5% (w/v),

Sodium citrate dihydrate, 0.4% (w/v),

Boric acid, 0.25% (w/v),

Sodium borate decahydrate, 0.41% (w/v), and

Potassium chloride 0.14% (w/v).