IP Library › Granted Patent US 9,498,476
Granted Patent B2
US 9,498,476 · App. 14/841,024 · Granted Nov 22, 2016

Crystalline form of 6-[(4S)-2-methyl-4-(2-naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyridazin-3-amine

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Quick Facts
Patent No.
US 9,498,476
App. No.
14/841,024
Granted
Nov 22, 2016
Kind
B2
Abstract

The present disclosure generally relates to a crystalline form of 6-[(4S)-2-methyl-4-(naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyridazin-3-amine. The present disclosure also generally relates to pharmaceutical compositions comprising the crystalline form, as well of methods of using a crystalline form in the treatment of depression and other conditions and methods for obtaining such crystalline form.

Claims (2)

1. A method of treating depression in a mammal in need thereof comprising administering to the mammal a therapeutically-effective amount of Form N-1 of

2. The method of claim 1 wherein the mammal is a human.

Assignments (8)
PARTIAL RELEASE OF FIRST LIEN INTELLECTUAL PROPERTY SECURITY AGREEMENT SUPPLEMENT Recorded Jun 3, 2025
From: APOLLO ADMINISTRATIVE AGENCY LLC
To: CURIA GLOBAL, INC.
Reel/Frame 071490/0880 →
CHANGE OF NAME Recorded May 20, 2025
From: ALBANY MOLECULAR RESEARCH, INC.
To: CURIA GLOBAL, INC.
Reel/Frame 071298/0097 →
SECURITY INTEREST Recorded Mar 7, 2025
From: CURIA GLOBAL, INC.; CURIA IP HOLDINGS, LLC; CURIA BIO, INC.
To: APOLLO ADMINISTRATIVE AGENCY LLC
Reel/Frame 070442/0908 →
RELEASE OF SECURITY INTEREST Recorded Nov 16, 2020
From: BARCLAYS BANK PLC, AS COLLATERAL AGENT
To: ALBANY MOLECULAR RESEARCH, INC.
Reel/Frame 054382/0326 →
RELEASE OF SECURITY INTEREST Recorded Oct 29, 2020
From: MORGAN STANLEY SENIOR FUNDING, INC., AS COLLATERAL AGENT
To: ALBANY MOLECULAR RESEARCH, INC.; AMRI BURLINGTON, INC.; CEDARBURG PHARMACEUTICALS, INC.; EUTICALS INC.; OSO BIOPHARMACEUTICALS MANUFACTURING, LLC
Reel/Frame 054252/0687 →
FIRST LIEN SECURITY AGREEMENT Recorded Sep 1, 2017
From: ALBANY MOLECULAR RESEARCH, INC.; AMRI BURLINGTON, INC.; CEDARBURG PHARMACEUTICALS, INC.; EUTICALS INC.; OSO BIOPHARMACEUTICALS MANUFACTURING, LLC-BY ITS SOLE MEMBER: ALO ACQUISITION LLC
To: BARCLAYS BANK, PLC AS COLLATERAL AGENT
Reel/Frame 043746/0621 →
SECOND LIEN SECURITY AGREEMENT Recorded Sep 1, 2017
From: ALBANY MOLECULAR RESEARCH, INC.; AMRI BURLINGTON, INC.; CEDARBURG PHARMACEUTICALS, INC.; EUTICALS INC.; OSO BIOPHARMACEUTICALS MANUFACTURING LLC-BY ITS SOLE MEMBER:ALO ACQUISITION LLC
To: MORGAN STANLEY SENIOR FUNDING, INC.
Reel/Frame 043746/0657 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 22, 2016
From: BRISTOL-MYERS SQUIBB COMPANY
To: ALBANY MOLECULAR RESEARCH, INC.
Reel/Frame 039116/0827 →