System and method for bronchial dilation
View Patent ↗A method of reducing bronchial constriction in a subject includes delivering energy to create one or more lesions on a main bronchus so as to transect pulmonary nerves sufficiently to reduce bronchial constriction in a lung of the patient distal to the main bronchus.
1. A system, comprising:
an implantable signal generator configured to generate energy to be delivered to nerve tissue proximate a bronchus or trachea of a patient; and
an electrode configured to be positioned proximate the bronchus or trachea so as to at least partially extend circumferentially about at least a portion of an inner or outer surface of the bronchus or trachea, the electrode operatively coupled to the implantable signal generator and configured to deliver energy from the implantable signal generator to the nerve tissue,
wherein the implantable signal generator is programmed to control delivery of energy through the electrode to the nerve tissue so as to have an effect on the patient, the effect being selected from the group consisting of: relieving bronchial smooth muscle contraction, inhibiting cough, facilitating nerve signal traffic to and/or from the lung of the patient to provide pulmonary maintenance, and combinations thereof.
2. The system of claim 1 , further wherein the implantable signal generator is programmed to inhibit adaptation of a nervous system of the patient to the delivery of energy to the nerve tissue.
3. The system of claim 1 , wherein the energy generated by the implantable signal generator comprises a blocking signal.
4. The system of claim 3 , wherein the implantable signal generator is programmed to deliver the blocking signal so as to inhibit adaptation by varying a frequency of the blocking signal.
5. The system of claim 3 , wherein the implantable signal generator is programmed to deliver the blocking signal so as to inhibit adaptation by varying a duty cycle of the blocking signal.
6. The system of claim 3 , wherein the implantable signal generator is programmed to deliver the blocking signal so as to prevent adaptation by varying an amplitude of the blocking signal.
7. The system of claim 3 , wherein the implantable signal generator is programmed to deliver the blocking signal so as to prevent adaptation by varying a pulse width of the blocking signal.
8. The system of claim 3 , wherein the implantable signal generator is programmed to deliver the blocking signal so as to prevent adaptation by delivering the blocking signal based at least in part on a circadian rhythm.
9. The system of claim 3 , wherein the implantable signal generator is programmed to deliver the blocking signal so as to prevent adaptation by deactivating the blocking signal for a predetermined period of time.
10. A system, comprising:
a signal generator configured to generate energy to be delivered to nerve tissue proximate a bronchus or trachea of a patient; and
an energy emitter configured to be implanted proximate the bronchus or trachea so as to at least partially extend circumferentially about and engage tissue of at least an inner surface or outer surface of the bronchus or trachea, the energy emitter operatively coupled to the signal generator and configured to deliver energy from the signal generator to the nerve tissue,
wherein the signal generator is programmed to control delivery of energy through the energy emitter to the nerve tissue so as to have an effect on the patient, the effect being selected from the group consisting of: relieving bronchial smooth muscle contraction, inhibiting cough, facilitating nerve signal traffic to and/or from the lung of the patient to provide pulmonary maintenance, and combinations thereof.
11. The system of claim 10 , further wherein signal generator is programmed to inhibit adaptation of a nervous system of the patient to the delivery of energy to the nerve tissue.
12. The system of claim 10 , wherein the energy generated by the signal generator comprises a blocking signal.
13. The system of claim 10 , wherein the signal generator is programmed to deliver the signal so as to inhibit adaptation by varying a frequency of the signal.
14. The system of claim 10 , wherein the signal generator is programmed to deliver the signal so as to inhibit adaptation by varying a duty cycle of the signal.
15. The system of claim 10 , wherein the signal generator is programmed to deliver the signal so as to prevent adaptation by varying an amplitude of the signal.
16. The system of claim 10 , wherein the signal generator is programmed to deliver the signal so as to prevent adaptation by varying a pulse width of the signal.
17. The system of claim 10 , wherein the signal generator is programmed to deliver the signal so as to prevent adaptation by delivering the signal based at least in part on a circadian rhythm.
18. The system of claim 10 , wherein the signal generator is programmed to deliver the signal so as to prevent adaptation by deactivating the signal for a predetermined period of time.
19. The system of claim 10 , wherein the signal generator is implantable.