IP Library Granted Patent US 9,566,213
Granted Patent B2
US 9,566,213 · App. 14/859,098 · Granted Feb 14, 2017

Implantable electroacupuncture system and method for treating dyslipidemia and obesity

Inventors: Jeffrey H. Greiner (Valencia, CA); David K. L. Peterson (Valencia, CA); Chuladatta Thenuwara (Castaic, CA); Stacy Greiner Chambliss (Valencia, CA)
Assignee: Valencia Technologies Corporation
A61H39/002A61F5/0026A61N1/36085A61N1/36117A61N1/36125A61N1/36175A61N1/375A61N1/3756A61N1/37205A61H2201/50A61H2201/5005A61H2201/5038A61H2201/5097A61N1/36153A61N1/36157A61N1/3758A61N1/3782Y10T29/49117
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Quick Facts
Patent No.
US 9,566,213
App. No.
14/859,098
Granted
Feb 14, 2017
Kind
B2
Abstract

An exemplary method of treating obesity or dyslipidemia of a patient includes 1) generating, by an electroacupuncture device implanted beneath a skin surface of the patient at an acupoint corresponding to at least one of a saphenous nerve and a peroneal nerve of the patient, stimulation sessions at a duty cycle that is less than 0.05, and 2) applying, by the electroacupuncture device in accordance with the duty cycle, the stimulation sessions to at least one of the saphenous nerve and the peroneal nerve by way of a central electrode and an annular electrode located on a housing of the electroacupuncture device.

Claims (46)

1. A method of treating obesity or dyslipidemia of a patient, comprising:

generating, by an electroacupuncture device implanted beneath a skin surface of the patient at an acupoint corresponding to at least one of a saphenous nerve and a peroneal nerve of the patient, stimulation sessions at a duty cycle that is less than 0.05, wherein

each stimulation session included in the stimulation sessions comprises a series of stimulation pulses,

the duty cycle is a ratio of T 3 to T 4 ,

each stimulation session included in the stimulation sessions has a duration of T 3 minutes and occurs at a rate of once every T 4 minutes, and

the electroacupuncture device comprises a central electrode of a first polarity centrally located on a first surface of a housing of the electroacupuncture device and an annular electrode of a second polarity and that is spaced apart from the central electrode; and

applying, by the electroacupuncture device, the stimulation sessions to at least one of the saphenous nerve and the peroneal nerve by way of the central electrode and the annular electrode in accordance with the duty cycle.

2. The method of claim 1 , wherein the acupoint comprises at least one of acupoints ST 36 , SP 4 , ST 37 , ST 40 , SP 6 , SP 9 , K 16 , and LR 8 .

3. The method of claim 1 , wherein T 3 is at least 10 minutes and less than 60 minutes, and wherein T 4 is at least 1440 minutes.

4. The method of claim 1 , further comprising:

receiving, by the electroacupuncture device from a device external to the electroacupuncture device, a control command that sets the times T 3 and T 4 to appropriate values configured to treat the obesity or the dyslipidemia;

wherein the generating of the stimulation sessions is performed in accordance with the control command.

5. The method of claim 4 , wherein the receiving of the control command comprises detecting, with an electromagnetic field sensor included in the electroacupuncture device, a magnetic field generated by the device external to the electroacupuncture device.

6. The method of claim 1 , wherein the housing is coin-sized and coin-shaped.

7. The method of claim 1 , wherein the annular electrode is located on the first surface of the housing.

8. The method of claim 1 , wherein the annular electrode comprises a ring electrode located around a perimeter edge of the housing.

9. The method of claim 1 , wherein the applying of the stimulation sessions to at least one of the saphenous nerve and the peroneal nerve further comprises applying the stimulation sessions by way an electrode included on a lead connected to the electroacupuncture device.

10. The method of claim 1 , further comprising powering electronic circuits within the electroacupuncture device with a battery having an internal impedance of at least 5 ohms.

11. An electroacupuncture device for treating obesity or dyslipidemia of a patient, comprising:

a housing configured to be implanted beneath a skin surface of the patient at an acupoint corresponding to at least one of a saphenous nerve and a peroneal nerve of the patient;

a central electrode of a first polarity and centrally located on a first surface of the housing;

an annular electrode of a second polarity and that surrounds the central electrode on the first surface of the housing, the annular electrode being spaced apart from the central electrode; and

pulse generation circuitry located within the housing and electrically coupled to the annular and central electrodes, wherein the pulse generation circuitry

generates stimulation sessions at a duty cycle that is less than 0.05, and

applies the stimulation sessions to at least one of the saphenous nerve and the peroneal nerve by way of the central electrode and the annular electrode in accordance with the duty cycle,

wherein

each stimulation session included in the stimulation sessions comprises a series of stimulation pulses,

the duty cycle is a ratio of T 3 to T 4 , and

each stimulation session included in the stimulation sessions has a duration of T 3 minutes and occurs at a rate of once every T 4 minutes.

12. The electroacupuncture device of claim 11 , wherein the acupoint comprises at least one of acupoints ST 36 , SP 4 , ST 37 , ST 40 , SP 6 , SP 9 , K 16 , and LR 8 .

13. The electroacupuncture device of claim 11 , wherein T 3 is at least 10 minutes and less than 60 minutes, and wherein T 4 is at least 1440 minutes.

14. The electroacupuncture device of claim 11 , further comprising:

an electromagnetic field sensor that receives, from a device external to the electroacupuncture device, a control command that sets the times T 3 and T 4 to appropriate values configured to treat the obesity or the dyslipidemia;

wherein the pulse generation circuitry generates the stimulation sessions in accordance with the control command.

15. The electroacupuncture device of claim 11 , wherein the housing is coin-sized and coin-shaped.

16. The electroacupuncture device of claim 11 , wherein the annular electrode is located on the first surface of the housing.

17. The electroacupuncture device of claim 11 , wherein the annular electrode comprises a ring electrode located around a perimeter edge of the housing.

18. A system for treating obesity or dyslipidemia of a patient, comprising:

means for generating, within an electroacupuncture device implanted beneath a skin surface of the patient at an acupoint corresponding to at least one of a saphenous nerve and a peroneal nerve of the patient, stimulation sessions at a duty cycle that is less than 0.05, wherein

each stimulation session included in the stimulation sessions comprises a series of stimulation pulses,

the duty cycle is a ratio of T 3 to T 4 ,

each stimulation session included in the stimulation sessions has a duration of T 3 minutes and occurs at a rate of once every T 4 minutes, and

the electroacupuncture device comprises a central electrode of a first polarity centrally located on a first surface of a housing of the electroacupuncture device and an annular electrode of a second polarity and that is spaced apart from the central electrode; and

means for applying the stimulation sessions to at least one of the saphenous nerve and the peroneal nerve by way of the central electrode and the annular electrode in accordance with the duty cycle.

19. The system of claim 18 , wherein the acupoint comprises at least one of acupoints ST 36 , SP 4 , ST 37 , ST 40 , SP 6 , SP 9 , K 16 , and LR 8 .

20. The system of claim 18 , wherein T 3 is at least 10 minutes and less than 60 minutes, and wherein T 4 is at least 1440 minutes.

Assignments (5)
RELEASE OF SECURITY INTEREST Recorded May 6, 2026
From: MEDTRONIC, INC.
To: VALENCIA BIOSCIENCE, INC.
Reel/Frame 075721/0223 →
SECURITY INTEREST Recorded Oct 27, 2023
From: VALENCIA BIOSCIENCE, INC.
To: MEDTRONIC, INC.
Reel/Frame 065382/0738 →
SECURITY INTEREST Recorded Aug 4, 2021
From: VALENCIA BIOSCIENCE, INC.
To: MEDTRONIC, INC.
Reel/Frame 057088/0352 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 3, 2020
From: VALENCIA TECHNOLOGIES CORPORATION
To: VALENCIA BIOSCIENCE, INC.
Reel/Frame 053684/0656 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 18, 2015
From: GREINER, JEFFREY H.; PETERSON, DAVID K. L.; THENUWARA, CHULADATTA; GREINER, STACY O.
To: VALENCIA TECHNOLOGIES CORPORATION
Reel/Frame 036604/0903 →
Continuity (10)
Continuation 13736033 · Jan 7, 2013
Continuation In Part 13622497 · Sep 19, 2012
Provisional Application 61606995 · Mar 6, 2012
Provisional Application 61609875 · Mar 12, 2012
Provisional Application 61672257 · Jul 16, 2012
Provisional Application 61672661 · Jul 17, 2012
Provisional Application 61673254 · Jul 19, 2012
Provisional Application 61674691 · Jul 23, 2012
Provisional Application 61676275 · Jul 26, 2012
Related Publication 20160008221A1 · Jan 14, 2016