Lubricious medical device elements
View Patent ↗Embodiments of the invention include medical device elements formed from polymers with lubricious properties. In an embodiment, a method of forming a medical device element is included. The method can include mixing a first polymeric component and a second polymeric component to form a polymer mixture. The method can further include forming the polymer mixture into the medical device element. The method can also include treating the polymer mixture with at least one of an acid or a base. In an embodiment, a medical device is included. The medical device can include a lubricious element, the lubricious element comprising a mixture of a first polymeric component and a second polymeric component. The second polymeric component can include a polymer that is treated with at least one of an acid or a base after formation of the element. Other embodiments are also included herein.
1. A method of forming a medical device comprising:
mixing a first polymeric component comprising a polyurethane, a second polymeric component comprising a methyl vinyl ether and maleic anhydride copolymer, and a photoactivatable cross-linking agent to form a polymer mixture;
forming the polymer mixture into a substrate of the medical device by applying the polymer mixture onto a form or mold and then removing the form or mold from the polymer mixture; and
treating a surface of the polymer mixture with at least one of an acid or a base.
2. The method of claim 1 , the first polymeric component further comprising a polymer selected from the group consisting of, polystyrene, polysiloxane, and polyvinyl chloride.
3. The method of claim 1 , the second polymeric component comprising a subunit that undergoes a reaction to yield a carboxylic acid group upon exposure to at least one of an acid or a base.
4. The method of claim 1 , the second polymeric component comprising a subunit that undergoes a ring opening reaction upon exposure to at least one of an acid or a base.
5. The method of claim 1 , the second polymeric component comprising a polymer having a molecular weight of about 1,900 kD to about 2,100 kD.
6. The method of claim 1 , wherein the polymer mixture contains from about 1:1 to about 3:1 of the first polymeric component to the second polymeric component by weight.
7. The method of claim 1 , wherein forming the polymer mixture into a substrate of the medical device comprises forming the polymer mixture into a hollow tube.
8. The method of claim 1 , wherein forming the polymer mixture into the substrate of the medical device by applying the polymer mixture onto a form or mold comprises applying the polymer mixture onto tubing and then removing the tubing from the polymer mixture.