Xanthophyll compositions and methods of use
View Patent ↗The present invention encompasses a carotenoid composition, a process for producing a carotenoid composition, and methods of use thereof.
1. A composition, the composition comprising soap derived from the saponification of a natural carotenoid-containing oleoresin, the soap comprising non-esterified xanthophyll particles and oleoresin components from the original natural carotenoid-containing oleoresin, wherein 90% of the non-esterified xanthophyll particles are less than 0.5 microns across the largest diameter and wherein the composition comprises at least 75 mg of non-esterified xanthophyll per gram of soap.
2. The composition of claim 1 , wherein at least 95% of the non-esterified xanthophyll particles are less than 0.5 microns across the largest diameter.
3. The composition of claim 2 , wherein at least 99% of the non-esterified xanthophyll particles are less than 0.5 microns across the largest diameter.
4. The composition of claim 1 , wherein at least 60% of the non-esterified xanthophyll is the all-trans isomer.
5. The composition of claim 4 , wherein at least 80% of the non-esterified xanthophyll is the all-trans isomer.
6. The composition of claim 1 , wherein the composition comprises at least 100 mg of non-esterified xanthophyll per gram soap.
7. The composition of claim 1 , wherein the composition further comprises less than about 15% of a free flow agent.
8. The composition of claim 1 , wherein the natural carotenoid-containing oleoresin is marigold oleoresin.
9. The composition of claim 1 , wherein the non-esterified xanthophyll particles comprise lutein.
10. The composition of claim 1 , wherein the non-esterified xanthophyll particles comprise zeaxanthin.
11. The composition of claim 1 , wherein the non-esterified xanthophyll particles comprise at least lutein and zeaxanthin.
12. The composition of claim 1 , wherein the soap is derived from the saponification of a natural carotenoid-containing oil produced from the natural carotenoid-containing oleoresin.
13. The composition of claim 1 , wherein the composition retains greater than 98% of the initial non-esterified total xanthophyll concentration when stored at room temperature in an oxygen permeable dark bag for one month.
14. The composition of claim 1 , wherein the composition retains greater than 90% of the initial non-esterified total xanthophyll concentration when stored at room temperature, in an oxygen permeable dark bag, mixed with animal feed or animal feed ingredients, for one month.
15. An animal feed, the animal feed comprising the composition of claim 1 .
16. A method of increasing the pigmenting efficacy of an animal feed, the method comprising combining the animal feed with a composition of claim 1 .
17. The method of claim 16 , wherein the animal feed is an egg laying fowl feed or aquaculture feed.
18. A method of increasing the carotenoid content of egg yolk, the method comprising administering a composition of claim 1 to egg laying fowl.
19. The method of claim 18 , wherein the egg laying fowl are chickens or ducks.
20. A method of increasing the carotenoid content of skin in a subject, the method comprising administering a composition of claim 1 to the subject.
21. A method of increasing the carotenoid content of an animal feed, the method comprising combining a composition of claim 1 with the animal feed.
22. The method of claim 21 , wherein the carotenoid is a xanthophyll.
23. The method of claim 21 , wherein the xanthophyll is lutein.