IP Library Granted Patent US 9,359,626
Granted Patent B2
US 9,359,626 · App. 14/861,366 · Granted Jun 7, 2016

Glucosyltransferase enzymes

Inventors: Perry G Caimi (Kennett Square, PA); Susan Marie Hennessey (Avondale, PA); Mark S Payne (Wilmington, DE)
Assignee: E I DU PONT DE NEMOURS AND COMPANY
C12P19/18C08B37/0009C12N9/1051C12P19/04C12Y204/01
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Quick Facts
Patent No.
US 9,359,626
App. No.
14/861,366
Granted
Jun 7, 2016
Kind
B2
Abstract

A process for producing poly alpha-1,3-glucan with reduced molecular weight is disclosed. The process comprises contacting water, sucrose, a polar organic solvent, and a glucosyltransferase enzyme in a solution to produce poly alpha-1,3-glucan. This contacting step results in the production of poly alpha-1,3-glucan having a reduced molecular weight compared to the molecular weight of a poly alpha-1,3-glucan made in the absence of the polar organic solvent.

Claims (12)

1. An isolated protein comprising SEQ ID NO: 14, wherein said protein has glucosyltransferase activity and produces poly alpha-1,3-glucan having at least 50% alpha-1,3 glycosidic linkages.

2. An isolated protein consisting of SEQ ID NO: 14.

3. An isolated protein that is a fragment of the polypeptide of SEQ ID NO: 32, wherein said fragment consists of an amino acid sequence that is at least 95% identical with SEQ ID NO: 14, and wherein said protein has glucosyltransferase activity and produces poly alpha-1,3-glucan having at least 50% alpha-1,3 glycosidic linkages.

4. The protein of claim 3 , wherein the fragment consists of an amino acid sequence that is at least 97% identical with SEQ ID NO:14.

5. The protein of claim 4 , wherein the fragment consists of an amino acid sequence that is at least 98% identical with SEQ ID NO:14.

6. The protein of claim 3 , wherein said poly alpha-1,3-glucan has at least 95% alpha-1,3 glycosidic linkages.

7. A reaction solution comprising water, sucrose and a protein comprising SEQ ID NO: 14, wherein said protein has glucosyltransferase activity and produces poly alpha-1,3-glucan having at least 50% alpha-1,3 glycosidic linkages.

8. A reaction solution comprising water, sucrose and a protein consisting of SEQ ID NO: 14.

9. A reaction solution comprising water, sucrose and a protein that is a fragment of the polypeptide of SEQ ID NO: 32, wherein said fragment consists of an amino acid sequence that is at least 95% identical with SEQ ID NO: 14, and wherein said protein has glucosyltransferase activity and produces poly alpha-1,3-glucan having at least 50% alpha-1,3 glycosidic linkages.

10. The reaction solution of claim 9 , wherein the fragment consists of an amino acid sequence that is at least 97% identical with SEQ ID NO:14.

11. The reaction solution of claim 10 , wherein the fragment consists of an amino acid sequence that is at least 98% identical with SEQ ID NO:14.

12. The reaction solution of claim 9 , wherein said poly alpha-1,3-glucan has at least 95% alpha-1,3 glycosidic linkages.

Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 28, 2020
From: DUPONT INDUSTRIAL BIOSCIENCES USA, LLC
To: NUTRITION & BIOSCIENCES USA 4, INC.
Reel/Frame 055028/0496 →
CORRECTIVE ASSIGNMENT TO CORRECT THE ENTITY TYPE PREVIOUSLY RECORDED AT REEL: 049879 FRAME: 0043. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT. Recorded Sep 6, 2019
From: E. I. DU PONT DE NEMOURS AND COMPANY
To: DUPONT INDUSTRIAL BIOSCIENCES USA, LLC
Reel/Frame 050300/0408 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 26, 2019
From: E. I. DU PONT DE NEMOURS AND COMPANY
To: DUPONT INDUSTRIAL BIOSCIENCES USA, LLC
Reel/Frame 049879/0043 →
Continuity (3)
Division 14476790 · Sep 4, 2014
Provisional Application 61873851 · Sep 5, 2013
Related Publication 20160002693A1 · Jan 7, 2016