Wound dressing materials and methods of making thereof
Disclosed is a wound dressing material comprising a substrate, about 2.5% to about 8% by weight of a bicarbonate, and a film-forming agent, the film-forming agent serving as a binder for said bicarbonate to said substrate, the film-forming agent and the bicarbonate being present in a ratio of between 1:2 and 2:1 with respect to one another. Also disclosed are a method for preparing a wound dressing material and a method for treating a wound.
1. A method of making a wound dressing material, the method comprising:
providing a substrate;
applying an aqueous wound dressing composition to the substrate, said wound dressing composition comprising a bicarbonate and a film-forming agent, the bicarbonate and the film forming agent being present in the wound dressing composition at a ratio of from 1:2 to 2:1 relative to each other; and
drying at least a part of the wound dressing material having at least a portion of the wound dressing composition applied thereto to yield a wound dressing material that includes about 2.5% to about 8% by weight of said bicarbonate,
wherein the film forming agent comprises a polysaccharide, chitosan, povidone, gelatin, a polyethylene glycol, hydroxyethylcellulose, hypromellose, a polymethacrylate, poly(methyl vinyl ether/maleic anhydride), shellac, or combinations thereof.
2. The method according to claim 1 , wherein said bicarbonate comprises sodium bicarbonate.
3. The method according to claim 1 , wherein said substrate comprises a cellulosic material.
4. The method according to claim 3 , wherein said substrate further comprises a polyester.
5. The method according to claim 1 , wherein the composition further includes at least one of a buffering agent, anti-microbial agent, and nutritive agent.
6. The method of claim 1 , further comprising pressing out at least some of the composition from the wound dressing.
7. The method of claim 1 , further comprising applying backing to the wound dressing material.
8. The method of claim 1 , further comprising applying backing to the wound dressing material.
9. A method of making a wound dressing material, the method comprising:
providing a substrate;
applying an aqueous wound dressing composition to the substrate, said wound dressing composition comprising a bicarbonate and a film-forming agent, the bicarbonate and the film forming agent being present in the wound dressing composition at a ratio of from 1:2 to 2:1 relative to each other; and
drying at least a part of the wound dressing material having at least a portion of the wound dressing composition applied thereto to yield a wound dressing material that includes about 2.5% to about 8% by weight of said bicarbonate,
wherein the film forming agent is a polyethylene glycol having a molecular weight of about 1,000 to about 10,000.
10. A method of making a wound dressing material, the method comprising:
providing a substrate;
applying an aqueous wound dressing composition to the substrate, said wound dressing composition comprising a bicarbonate and a film-forming agent, the bicarbonate and the film forming agent being present in the wound dressing composition at a ratio of from 1:2 to 2:1 relative to each other; and
drying at least a part of the wound dressing material having at least a portion of the wound dressing composition applied thereto to yield a wound dressing material that includes about 2.5% to about 8% by weight of said bicarbonate,
wherein the composition further including includes a plasticizer.
11. The method according to claim 10 , wherein the plasticizer comprises glycerin.
12. The method according to claim 10 , wherein said bicarbonate comprises sodium bicarbonate.
13. The method according to claim 10 , wherein said substrate comprises a cellulosic material.
14. The method according to claim 13 , wherein said substrate further comprises a polyester.
15. The method according to claim 10 , wherein the composition further includes at least one of a buffering agent, anti-microbial agent, and nutritive agent.
16. The method of claim 10 , further comprising pressing out at least some of the composition from the wound dressing.