IP Library › Granted Patent US 9,493,609
Granted Patent B2
US 9,493,609 · App. 14/865,362 · Granted Nov 15, 2016

N-maleimidyl polymer derivatives

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Quick Facts
Patent No.
US 9,493,609
App. No.
14/865,362
Granted
Nov 15, 2016
Kind
B2
Abstract

The invention is directed to multi-functional N-maleimidyl polymer derivatives comprising a water soluble and non-peptidic polymer backbone having a terminal carbon, such as a poly(alkylene glycol), the terminal carbon of the polymer backbone being directly bonded to the nitrogen atom of a N-maleimidyl moiety without a linking group therebetween. The invention also provides two methods of preparing such linkerless N-maleimidyl polymer derivatives.

Claims (4)

1. A multi-functional N-maleimidyl polymer derivative having the formula:

wherein:

X is aldehyde; and

n is about 20 to about 4000.

Assignments (2)
RELEASE OF SECURITY INTEREST Recorded Apr 17, 2020
From: TC LENDING, LLC, AS COLLATERAL AGENT
To: NEKTAR THERAPEUTICS
Reel/Frame 053180/0009 →
SECURITY INTEREST Recorded Mar 15, 2016
From: NEKTAR THERAPEUTICS
To: TC LENDING, LLC, AS A COLLATERAL AGENT
Reel/Frame 037990/0511 →