IP Library Granted Patent US 10,252,081
Granted Patent B2
US 10,252,081 · App. 14/865,703 · Granted Apr 9, 2019

Apparatus and method using automatic generation of a base dose

Inventors: Juha Kauppinen (Espoo, FI); Janne I. Nord (Espoo, FI)
Assignee: Varian Medical Systems International AG
A61N5/1031A61N5/10A61N5/103A61N5/1038A61N5/1042A61N5/1045A61N5/1047
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Quick Facts
Patent No.
US 10,252,081
App. No.
14/865,703
Granted
Apr 9, 2019
Kind
B2
Abstract

A control circuit forms a radiation therapy treatment plan by automatically generating a base dose that references dosing information from multiple sources (such as multiple information sources) and then using that base dose to optimize a radiation therapy treatment plan. That radiation therapy treatment plan is then used to administer radiation therapy to a patient. That automatically generated base dose can represent any or all of earlier radiation therapy treatments for the patient, a same fraction as a dose presently being optimized per the radiation therapy treatment plan, and future planned fractions for the patient.

Claims (36)

1. A method comprising:

forming a radiation therapy treatment plan for a patient using a control circuit by:

automatically generating a base dose that references dosing information from multiple sources, the base dose constituting an aggregated per-patient metric that represents radiation dosages received in earlier radiation treatment sessions for the patient, previous radiation dosages received by the patient on a same day as a session for which the radiation therapy treatment plan is currently being formed, and planned future sessions for the patient; and

using the base dose to optimize a radiation therapy treatment plan; and

using the radiation therapy treatment plan to administer radiation therapy to a patient.

2. The method of claim 1 , wherein automatically generating the base dose comprises, at least in part, generating the base dose as a function of a particular treatment model such that the base dose is suitable for present use in optimizing the radiation therapy treatment plan.

3. The method of claim 1 , wherein using the base dose to optimize a radiation therapy treatment plan comprises, at least in part, using the base dose to limit an accumulation of radiation in a particular volume of the patient.

4. The method of claim 1 , wherein the multiple sources include at least one of:

treatment records for radiation therapy treatment previously delivered to the patient;

radiation therapy treatment plans for undelivered parallel treatment for the patient;

patient images; and

patient deformation information.

5. The method of claim 1 , wherein automatically generating a base dose that references dosing information from multiple sources comprises, at least in part, individually weighting the dosing information from different sources.

6. The method of claim 5 , wherein individually weighting the dosing information from different sources comprises individually weighting the dosing information as a function, at least in part of at least one of:

relevancy of the source; and

accuracy of the source.

7. The method of claim 1 , wherein automatically generating a base dose that references dosing information from multiple sources comprises, at least in part, producing a base dose and a corresponding indication of uncertainty.

8. The method of claim 1 , wherein automatically generating a base dose that references dosing information from multiple sources comprises using biological modeling to estimate a single dose distribution having a same biological effect as a combined effect of the multiple sources.

9. An apparatus comprising:

a control circuit configured to form a radiation therapy treatment plan for a patient by:

automatically generating a base dose that references dosing information from multiple sources, the base dose constituting an aggregated per-patient metric that represents radiation dosages received in earlier radiation treatment sessions for the patient, previous radiation dosages received by the patient on a same day as a session for which the radiation therapy treatment plan is currently being formed, and planned future sessions for the patient; and

using the base dose to optimize a radiation therapy treatment plan: and

a radiation therapy treatment platform configured to use the radiation therapy treatment plan to administer the radiation therapy to a patient.

10. The apparatus of claim 9 , wherein the control circuit is configured to automatically generate the base dose by, at least in part generating the base dose as a function of a particular treatment model such that the base dose is suitable for present use in optimizing the radiation therapy treatment plan.

11. The apparatus of claim 9 , wherein the control circuit is configured to use the base dose to optimize a radiation therapy treatment plan by, at least in part, using the base dose to limit an accumulation of radiation in a particular volume of the patient.

12. The apparatus of claim 9 , wherein the multiple sources include at least one of:

treatment records for radiation therapy treatment previously delivered to the patient;

radiation therapy treatment plans for undelivered parallel treatment for the patient;

patient images; and

patient deformation information.

13. The apparatus of claim 9 , wherein the control circuit is configured to automatically generate a base dose that references dosing information from multiple sources by, at least in part, individually weighting the dosing information from different sources.

14. The apparatus of claim 13 , wherein the control circuit is configured to individually weight the dosing information from different sources by individually weighting the dosing information as a function, at least in part, of at least one of:

relevancy of the source; and

accuracy of the source.

15. The apparatus of claim 9 , wherein the control circuit is configured to automatically generate a base dose that references dosing information from multiple sources by at least in part, producing a base dose and a corresponding indication of uncertainty.

16. The apparatus of claim 9 , wherein the control circuit is configured to automatically generate a base dose that references dosing information from multiple sources by using biological modeling to estimate a single dose distribution having a same biological effect as a combined effect of the multiple sources.

Assignments (2)
CHANGE OF NAME Recorded Jan 25, 2024
From: VARIAN MEDICAL SYSTEMS INTERNATIONAL AG
To: SIEMENS HEALTHINEERS INTERNATIONAL AG
Reel/Frame 066369/0779 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 30, 2015
From: KAUPPINEN, JUHA; NORD, JANNE I.
To: VARIAN MEDICAL SYSTEMS INTERNATIONAL AG
Reel/Frame 036693/0727 →
Continuity (1)
Related Publication 20170087382A1 · Mar 30, 2017
Cited By (4)
US 12,383,765 US 12,440,701 US 12,453,866 US 12,491,377