Computed tomography enhanced fluoroscopic system, device, and method of utilizing the same

1. A method of enhanced navigation comprising:

planning a navigation path using a first data set of computed tomography images of a branched luminal network previously acquired, the navigation path defining a route to be followed through the branched luminal network to a target;

navigating a marker placement device to the target by following the route of the navigation path;

placing a plurality of markers in tissue proximate the target using the marker placement device;

acquiring a second data set of computed tomography images of the branched luminal network including the plurality of markers;

generating a three-dimensional model of the branched luminal network from the second data set of computed tomography images;

planning a second navigation path through the branched luminal network using the three-dimensional model generated, the second navigation path defining a second route to be followed through the branched luminal network to the target for a second navigation to the target;

navigating a medical instrument to the second target by following the second route of the second navigation path;

capturing fluoroscopic data of tissue proximate the plurality of markers;

identifying a slice of the second data set of computed tomography images having a marker position and orientation corresponding to a marker position and orientation within the fluoroscopic data;

registering the fluoroscopic data to the second data set of computed tomography images based on the identified slice;

creating a composite fluoroscopic image including:

the fluoroscopic data;

an object derived from the second data set of computed tomography images;

a representation of the branched luminal network from the second data set of computed tomography images; and

the second route of the second navigation path through the branched luminal network from the second data set of the computed tomography images, wherein the object, the representation of the branched luminal network and the second route of the second navigation path are fused with the fluoroscopic data; and

displaying the composite fluoroscopic image on a graphical user interface.

2. The method according to claim 1 , further comprising retrieving a sample of tissue proximate the target for biopsy.

3. The method according to claim 1 , further comprising:

displaying a representation of the second data set of computed tomography images on the graphical user interface; and

displaying the fluoroscopic data on the graphical user interface.

4. The method according to claim 1 , wherein the first target and the second target include the same area of interest.

5. The method according to claim 1 , wherein the creating the composite fluoroscopic image includes at least one of fusing, superimposing, or overlaying the second data set of computed tomography images with the fluoroscopic data.

6. The method according to claim 1 , wherein the capturing fluoroscopic data of the tissue proximate the plurality of markers includes capturing fluoroscopic video.

7. The method according to claim 1 , wherein the capturing fluoroscopic data of the tissue proximate the plurality of markers includes capturing at least one fluoroscopic image.

8. The method according to claim 7 , further comprising activating a microwave ablation device to ablate tissue proximate the second target.

9. The method according to claim 1 , further comprising:

analyzing the composite fluoroscopic image and determining whether the medical instrument is correctly positioned relative to the second target; and

adjusting a position of the medical instrument relative to the second target.

10. The method according to claim 9 , further comprising:

acquiring a second fluoroscopic data set of the tissue proximate the second target using a fluoroscope from a second perspective such that a three-dimensional position of the medical instrument is viewable from a different angle.

11. The method according to claim 10 , further comprising:

analyzing the second fluoroscopic data to determine whether the three-dimensional position of the medical instrument relative to the second target is correct; and

adjusting the three-dimensional position of the medical instrument relative to the second target.

12. A non-transitory computer readable storage medium including instructions that when executed by a computing device cause the computing device to:

plan a navigation path using a first data set of computed tomography images of a branched luminal network previously acquired, the navigation path defining a route to be followed through the branched luminal network to a target;

enable navigation of a marker placement device to the target by displaying the route of the navigation path;

acquire a second data set of computed tomography images of the branched luminal network including a plurality of markers previously placed in tissue proximate the target;

generate a three-dimensional model of the branched luminal network from the second data set of computed tomography images;

plan a second navigation path through the branched luminal network using the three-dimensional model generated, the second navigation path defining a second route to be followed through the branched luminal network to the target for a second navigation to the target;

enable navigation of a medical instrument to the second target by displaying the second route of the second navigation path;

capture fluoroscopic data of tissue proximate the plurality of markers using a fluoroscope;

identify a slice of the second data set of computed tomography images having a marker position and orientation corresponding to a marker position and orientation within the fluoroscopic data;

register the fluoroscopic data to the second data set of computed tomography images based on the identified slice;

create a composite fluoroscopic image including:

the fluoroscopic data;

an object derived from the second data set of computed tomography images;

a representation of the branched luminal network from the second data set of computed tomography images; and

the second route of the second navigation path through the branched luminal network from the second data set of the computed tomography images, wherein the object, the representation of the branched luminal network and the second route of the second navigation path are fused with the fluoroscopic data; and

display the composite fluoroscopic image on a graphical user interface.

13. The non-transitory computer readable storage medium according to claim 12 , wherein the instructions when executed further cause the computing device to:

display a representation of the second data set of computed tomography images on the graphical user interface; and

display the fluoroscopic data on the graphical user interface.

14. The non-transitory computer readable storage medium according to claim 12 , wherein the first target and the second target include the same area of interest.

15. The non-transitory computer readable storage medium according to claim 12 , wherein the instructions when executed further cause the computing device to fuse, superimpose, or overlay the second data set of computed tomography images with the fluoroscopic data.

16. The non-transitory computer readable storage medium according to claim 12 , wherein the instructions when executed further cause the computing device to analyze the composite fluoroscopic image and determine whether the medical instrument is correctly positioned relative to the second target.

17. The non-transitory computer readable storage medium according to claim 12 , wherein the instructions when executed further cause the computing device to acquire a second fluoroscopic data set of the second target using a fluoroscope from a second perspective such that a three-dimensional position of the medical instrument is viewable from a different angle.

18. The non-transitory computer readable storage medium according to claim 17 , wherein the instructions when executed further cause the computing device to analyze the second fluoroscopic data to determine whether the three-dimensional position of the medical instrument relative to the second target is correct.