IP Library › Granted Patent US 10,155,001
Granted Patent B2
US 10,155,001 · App. 14/897,970 · Granted Dec 18, 2018

RAC1 inhibitors for inducing bronchodilation

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Quick Facts
Patent No.
US 10,155,001
App. No.
14/897,970
Granted
Dec 18, 2018
Kind
B2
Abstract

The invention relates to a Rac1 inhibitor for use as bronchodilator in a patient in need thereof. The invention provides a Rac1 inhibitor for use in a method for inducing bronchodilation in a patient in need thereof. The invention also relates to a Rac1 inhibitor for use in a method for reducing AHR in a patient in need thereof.

Claims (5)

1. A method for inducing bronchodilation in a patient in need thereof, comprising

administering to the patient a therapeutically effective amount of a Rac1 inhibitor, wherein said step of administering results in bronchodilation in the patient, and wherein said patient suffers from an airway disease in which airway inflammation is not involved.

2. The method according to claim 1 , wherein the patient in need thereof suffers from exercise-induced asthma in which airway inflammation is not involved.

3. The method according to claim 1 , wherein the patient in need thereof is a salbutamol-resistant patient.

4. The method according to claim 1 , wherein the patient suffers from a bronchoconstructive disorder which is not caused by airway inflammation.

Assignments (3)
MERGER Recorded Sep 7, 2023
From: UNIVERSITE DE NANTES
To: NANTES UNIVERSITE
Reel/Frame 064824/0596 →
CORRECTIVE ASSIGNMENT TO CORRECT THE FIRST ASSIGNOR DOC. DATE AND ASSIGNEE NAME PREVIOUSLY RECORDED AT REEL: 038010 FRAME: 0858. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT. Recorded Nov 30, 2016
From: SAUZEAU, VINCENT; ANDRE, GWENNAN; LOIRAND, GERVAISE; MAGNAN, ANTOINE; LAIR, DAVID
To: INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE); CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS); UNIVERSITE DE NANTES; CENTRE HOSPITALIER UNIVERSITAIRE DE NANTES
Reel/Frame 040767/0820 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 17, 2016
From: SAUZEAU, VINCENT; ANDRE, GWENNAN; LOIRAND, GERVAISE; MAGNAN, ANTOINE; LAIR, DAVID
To: INSERM (INSTITUTE NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE); CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS); UNIVERSITE DE NANTES
Reel/Frame 038010/0858 →