IP Library Granted Patent US 10,857,090
Granted Patent B2
US 10,857,090 · App. 14/902,714 · Granted Dec 8, 2020

Oral compositions

Inventors: Natalia Yudina (London, CA); Maxim Daniel Seferovic (London, CA)
Assignee: Stellar Biome Inc.
A61K8/99A61K8/64A61K35/747A61Q11/00A61K2800/5922
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Quick Facts
Patent No.
US 10,857,090
App. No.
14/902,714
Granted
Dec 8, 2020
Kind
B2
Abstract

Compositions for use in oral hygiene contain a Lactobacillus helveticus strain. Compositions further containing a Lactobacillus plantarum strain, especially Lactobacillus plantarum SD5870, are particularly effective. The combination of Lactobacillus helveticus LAFTI L10 and Lactobacillus plantarum SD5870 synergistically improves oral hygiene. The compositions are particularly useful against dental caries.

Claims (9)

1. A method of treating an oral condition or disease in a subject, the method comprising orally administering a composition comprising an effective amount of a probiotic used for treating or preventing an oral condition or disease in a subject, the probiotic comprises a Lactobacillus helveticus strain wherein the oral condition or disease is selected from dental caries, halitosis, gingivitis, mouth ulcers, aphthous stomatitis, candidiasis, and combinations thereof, wherein the Lactobacillus helveticus strain is selected from Lactobacillus helveticus LAFTI L10, Lactobacillus helveticus R0052, or a mixture thereof.

2. The method of claim 1 , wherein the Lactobacillus helveticus strain is Lactobacillus helveticus LAFTI L10.

3. The method of claim 1 , wherein the probiotic further comprises a Lactobacillus plantarum strain.

4. The method of claim 3 , wherein the Lactobacillus plantarum strain comprises Lactobacillus plantarum SD5870.

5. The method of claim 1 , wherein the probiotic further comprises one or more bifidobacteria.

6. The method of claim 5 , wherein the bifidobacteria comprises Bifidobacterium longum SD5846.

7. The method of claim 1 , wherein the composition further comprises a remineralization agent.

8. The method of claim 7 , wherein the remineralization agent comprises casein phosphate peptide-amorphous calcium phosphate.

9. The method of claim 1 , wherein the oral condition or disease is dental caries.

Assignments (2)
CHANGE OF NAME Recorded Mar 24, 2020
From: INTEGRA MEDICAL INC.
To: STELLAR BIOME INC.
Reel/Frame 052219/0032 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 5, 2016
From: YUDINA, NATALIA; SEFEROVIC, MAXIM DANIEL
To: INTEGRA MEDICAL INC.
Reel/Frame 037673/0633 →
Continuity (2)
Provisional Application 61843158 · Jul 5, 2013
Related Publication 20160166501A1 · Jun 16, 2016