IP Library Granted Patent US 10,310,097
Granted Patent B2
US 10,310,097 · App. 14/902,796 · Granted Jun 4, 2019

Gamma probe with hand-piece control of detection parameters

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Quick Facts
Patent No.
US 10,310,097
App. No.
14/902,796
Filed
Jan 4, 2016
Granted
Jun 4, 2019
Kind
B2
Art Unit
3793
USPC
600/436
Abstract

Apparatus, techniques and systems are described for facilitating identification of a target area during a probe-guided radio-localization surgical procedure. The described apparatus, techniques and systems can be used to implement a nuclear-uptake mode controller integrated into a probe to allow a user to instantly switch between multiple nuclear-uptake modes directly from the probe hand-piece. For example, a nuclear-uptake mode controller integrated into the probe can be used to instantly switch between a high-sensitivity nuclear-uptake mode and a high-resolution nuclear-uptake mode to effectively identify the target area in the presence of interfering nuclear signals by better matching the probe's nuclear detection parameters to a search task for that target area.

Claims (36)

1. A handheld nuclear-uptake surgical probe for performing radio-localization of nuclear-emitting tissues, nuclear-uptake surgical probe comprising:

a handle;

a nuclear-uptake mode controller configured to selectively set a photon energy acceptance window of the handheld surgical probe; and

a switch located on the handle and communicatively coupled to the nuclear-uptake mode controller to selectively initiate setting of the photon energy acceptance window.

2. The handheld nuclear-uptake surgical probe of claim 1 , wherein the nuclear-uptake mode controller is integrated into a handle of the handheld nuclear-uptake surgical probe.

3. The handheld nuclear-uptake surgical probe of claim 1 , wherein the switch comprises a physical switch.

4. The handheld nuclear-uptake surgical probe of claim 1 , wherein the switch comprises a touch screen.

5. The handheld nuclear-uptake surgical probe of claim 1 , wherein the nuclear-uptake mode controller is sealed onto the handle of the handheld nuclear-uptake surgical probe to satisfy a sterile environment.

6. The handheld nuclear-uptake surgical probe of claim 1 , wherein the nuclear-uptake mode controller is configured to receive an enclosure to seal the nuclear-uptake mode controller onto the handle to satisfy a sterile environment.

7. The handheld nuclear-uptake surgical probe of claim 1 , comprising a sensor unit for selectively detecting gamma photons associated with nuclear-emitting tissues based at least in part on changes to the photon energy acceptance window.

8. The handheld nuclear-uptake surgical probe of claim 1 , comprising a communication medium configured to exchange data with an external probe system control unit.

9. The handheld nuclear-uptake surgical probe of claim 1 , wherein the communication medium comprises a wireless communication medium.

10. The handheld nuclear-uptake surgical probe of claim 1 , comprising a report unit configured to provide feedback to a user, wherein the feedback includes information associated with the selectively set photon energy acceptance window.

11. The handheld nuclear-uptake surgical probe of claim 1 , wherein the report unit is integrated into the handle of the handheld nuclear-uptake surgical probe.

12. The handheld nuclear-uptake surgical probe of claim 10 , wherein algorithms for generating the feedback are based at least in part on the selectively set photon energy acceptance window.

13. The handheld nuclear-uptake surgical probe of claim 10 , wherein the feedback information associated with the selectively set photon energy acceptance window includes identification of a currently set photon energy acceptance window.

14. The handheld nuclear-uptake surgical probe of claim 10 , wherein the feedback information comprises audible information.

15. A method of operating a handheld nuclear-uptake surgical probe, the method comprising:

receiving an input from a switch on the handheld nuclear-uptake surgical probe while the handheld nuclear-uptake surgical probe is in operation; and

responsive to the input, switching a photon energy acceptance window of the nuclear-uptake surgical probe.

16. The method of claim 15 , comprising:

responsive to the input, outputting feedback information from a reporting unit of the handheld nuclear-uptake surgical probe, wherein the feedback information includes information associated with the photon energy acceptance window of the nuclear-uptake surgical probe.

17. A handheld nuclear-uptake surgical probe for performing radio-localization of nuclear-emitting tissues, the handheld nuclear-uptake surgical probe comprising:

a collimator having an opening, the collimator configured to block gamma photons that are outside of collimator's field of view from passing through the collimator;

a gamma photon transparent window configured to block light from entering the opening of the collimator;

a scintillator configured to produce scintillation photons in proportion to energy of a gamma photon that passes through the collimator and enters the scintillator;

an optically-coupled photodiode configured to convert the scintillation photons produced by the scintillator to an induced charge pulse proportional to a number of the scintillation photons produced;

a backshield to block gamma photon signals from entering the optically-coupled photodiode from a backend opposite of the collimator opening;

a signal processing unit configured to process the induced charge pulse into a voltage pulse with amplitude representing the energy of the incoming gamma photon for culling into a count of accepted voltage pulses;

a switch disposed on the handheld nuclear-uptake surgical probe;

a nuclear-uptake mode controller integrated into the handheld nuclear-uptake surgical probe, the nuclear-uptake mode controller operatively coupled to the switch and configured to selectively switch a photon energy acceptance window of the handheld nuclear-uptake surgical probe; and

a wireless communication medium configured to exchange data with an external device.

18. The handheld nuclear-uptake surgical probe of claim 17 , wherein the nuclear-uptake mode controller is integrated into a handle of the handheld nuclear-uptake surgical probe.

19. The handheld nuclear-uptake surgical probe of claim 17 , wherein the physical switch located on a handle of the handheld nuclear-uptake surgical probe.

20. The handheld nuclear-uptake surgical probe of claim 17 , wherein the nuclear-uptake mode controller is sealed onto a handle of the handheld nuclear-uptake surgical probe to satisfy a sterile environment.

21. The handheld nuclear-uptake surgical probe of claim 17 , wherein the nuclear-uptake mode controller is configured to receive an enclosure to seal the nuclear-uptake mode controller onto the handheld nuclear uptake surgical probe to satisfy a sterile environment.

Assignments (5)
SECURITY INTEREST Recorded Apr 8, 2026
From: BIOTHERANOSTICS, INC.; GEN-PROBE INCORPORATED; GEN-PROBE PRODESSE, INC.; CYTYC CORPORATION; SUROS SURGICAL SYSTEMS, INC.; GYNESONICS, INC.; BOLDER SURGICAL, LLC; FAXITRON BIOPTICS, LLC; HEALTH BEACONS, INC.; HOLOGIC, INC.
To: ROYAL BANK OF CANADA, AS COLLATERAL AGENT
Reel/Frame 075462/0440 →
SECURITY INTEREST Recorded Oct 14, 2019
From: HOLOGIC, INC.; CYNOSURE, LLC; CYTYC CORPORATION; FAXITRON BIOPTICS, LLC; FOCAL THERAPEUTICS, INC.; GEN-PROBE INCORPORATED
To: BANK OF AMERICA, N.A., AS COLLATERAL AGENT
Reel/Frame 050719/0701 →
SECURITY INTEREST Recorded Oct 19, 2018
From: HOLOGIC, INC.; GEN-PROBE INCORPORATED; CYNOSURE, INC.; FAXITRON BIOPTICS, LLC
To: BANK OF AMERICA, N.A., AS COLLATERAL AGENT
Reel/Frame 047272/0347 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 2, 2018
From: COKIYA, INC.
To: FAXITRON BIOPTICS, LLC
Reel/Frame 047032/0607 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 19, 2016
From: YARNALL, STEPHEN T; KINDEM, JOEL; CONWELL, RICHARD L
To: COKIYA, INC.
Reel/Frame 037521/0595 →
Cited By (2)
US 12,228,689 US 12,699,191