Cartridge, cartridge reader and method for preventing reuse of the cartridge

1. A disposable fluidic cartridge comprising:

a body having a recess therein and a mechanically-actuatable mechanism disposed within the recess for effecting an operation of the fluidic cartridge; and

a machine-readable identification code on a breakable label, the breakable label covering at least a portion of the recess such that the portion of the breakable label covering the recess is configured to be broken upon insertion of a mechanical actuator into the recess to actuate the mechanically-actuatable mechanism, thereby rendering the identification code unreadable and preventing reuse of the fluidic cartridge,

wherein the mechanically-actuatable mechanism is a collapsible blister that contains a liquid component.

2. The disposable fluidic cartridge of claim 1 , wherein the collapsible blister is configured to expel its contents into a fluid pathway within the fluidic cartridge as it is collapsed.

3. The disposable fluidic cartridge of claim 1 , wherein the liquid component is one of a reagent, a lysis buffer, a wash buffer, and an elution buffer.

4. The disposable fluidic cartridge of claim 1 , wherein the machine-readable identification code is a bar-code or a QR-code.

5. The disposable fluidic cartridge of claim 1 , wherein the machine-readable identification code takes up an area on the breakable label, said area having a length and a width, and wherein at least one of the length and the width of said area is fully contained within the portion of the breakable label covering the recess.

6. The disposable fluidic cartridge of claim 1 , wherein the portion of the breakable label which covers the recess is separated from the remainder of the breakable label by a perforation to facilitate breaking of the label.

7. A method of using a disposable fluidic cartridge, the method comprising:

receiving the disposable fluidic cartridge within a cartridge reader, wherein the disposable fluidic cartridge includes a recess, a mechanically-actuatable mechanism disposed within the recess for effecting an operation of the disposable fluidic cartridge, and a machine-readable identification code on a breakable label covering at least a portion of the recess, the mechanically-actuatable mechanism being a collapsible blister that includes a liquid component;

attempting to detect an identification code on the breakable label on the disposable fluidic cartridge; and

upon successfully detecting the identification code, extending a mechanical actuator into the recess on the disposable fluidic cartridge to break the portion of the breakable label covering the recess, thereby rendering the identification code unreadable, and actuate the mechanically-actuatable mechanism.

8. The method of claim 7 , wherein the step of actuating the mechanically-actuatable mechanism comprises collapsing the collapsible blister to expel its contents into a fluid pathway within the disposable fluidic cartridge.

9. The method of claim 7 , further comprising the step of performing a diagnostic test on a sample in the disposable fluidic cartridge.

10. The method of claim 7 , wherein if the step of attempting to detect an identification code on the breakable label is unsuccessful, the cartridge reader rejects the disposable fluidic cartridge.

11. The method of claim 7 , wherein the liquid component is one of a reagent, a lysis buffer, a wash buffer, and an elution buffer.

12. The method of claim 7 , wherein the machine-readable identification code is a bar-code or a QR-code.

13. The method of claim 7 , wherein the step of attempting to detect an identification code is triggered upon insertion of the disposable fluidic cartridge into the cartridge reader.

14. The disposable fluidic cartridge of claim 1 , comprising polypropylene.

15. The disposable fluidic cartridge of claim 2 , wherein the fluid pathway is formed in a fluidic layer of the fluidic cartridge, said fluidic layer comprising polypropylene.

16. The disposable fluidic cartridge of claim 1 , wherein the recess is formed in a housing of the fluidic cartridge, said housing comprising acrylonitrile butadiene styrene.