IP Library Granted Patent US 9,381,116
Granted Patent B2
US 9,381,116 · App. 14/921,890 · Granted Jul 5, 2016

Subthreshold micropulse laser prophylactic treatment for chronic progressive retinal diseases

Inventors: Jeffrey K. Luttrull (Ojai, CA); Benjamin W. L. Margolis (Oakland, CA); David B. Chang (Tustin, CA)
Assignee: Ojai Retinal Technology, LLC
A61F9/00821A61B19/5212A61F9/008A61F9/00817A61F2009/00863
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Quick Facts
Patent No.
US 9,381,116
App. No.
14/921,890
Granted
Jul 5, 2016
Kind
B2
Abstract

A process for treating an eye to stop or delay the onset or symptoms of retinal diseases includes determining that the eye has a risk for a retinal disease before detectable retinal imaging abnormalities. A laser light beam is generated that provides preventative and protective treatment of the retinal tissue of the eye. At least a portion of the retinal tissue is exposed to the laser light beam without damaging the tissue. The retina may be retreated according to a set schedule or periodically according to the determination that the retina of the patient is to be retreated by monitored visual and/or retinal function or condition.

Claims (23)

1. A therapeutic process for treating an eye to stop or delay the onset or symptoms of retinal diseases, comprising the steps of:

determining that an eye has a risk for a retinal disease before detectable retinal imaging abnormalities;

generating a laser light beam that creates sublethal photocoagulation in retinal tissue to provide preventative and protective treatment of the retinal tissue of the eye; and

exposing at least a portion of retinal tissue, including at least a portion of the fovea, to the laser light beam without damaging the retinal or foveal tissue.

2. The process of claim 1 , wherein the determining step includes the step of ascertaining that the patient is at risk for age-related macular degeneration.

3. The process of claim 1 , wherein the determining step includes the step of conducting a test to establish that the patient has a risk for a retinal disease.

4. The process of claim 3 , wherein the test comprises a retinal physiology test.

5. The process of claim 1 , wherein the treated retina comprises the entire retina.

6. The process of claim 1 , wherein the exposing step includes exposing the laser light beam to the entire retina and fovea.

7. The process of claim 1 , including the step of periodically retreating the retina.

8. The process of claim 7 , including the step of periodically monitoring visual and/or retinal function or condition of the patient to determine when the retina of the patient is to be retreated.

9. The process of claim 7 , including the step of retreating the retina of the patient according to a set schedule.

10. The process of any of claims 1 - 9 , wherein the generating step comprises the step of generating a subthreshold sublethal micropulse laser light beam having a wavelength greater than 532 nm and a duty cycle of less than 10%.

11. The process of claim 10 , wherein the generated laser light beam has a pulse length of less than 500 milliseconds.

12. The process of claim 10 , wherein the generated laser light beam has a duty cycle of approximately 5% or less.

13. The process of claim 10 , wherein the generated laser light beam has an intensity of 100-590 watts per square centimeter.

14. The process of claim 10 , wherein the generated laser light beam has a wavelength of 550 nm-1300 nm.

15. The process of claim 14 , wherein the generated laser light beam has a wavelength of approximately 810 nm.

16. The process of any of claims 1 - 9 , including the step of manipulating the laser light beam into a geometric object or pattern of simultaneously generated and spaced apart treatment laser light spots.

17. The process of claim 16 , wherein the manipulating step comprises the step of creating a predetermined number of simultaneously generated laser light spots to completely and confluently cover a desired treatment area.

18. The process of claim 16 , wherein the geometric object or pattern of laser light spots cover the entire retina.

19. The process of claim 16 , including the step of controllably moving the geometric object or pattern of laser light spots to treat adjacent retinal tissue.

20. The process of claim 19 , wherein the moving step includes the step of incrementally moving the laser light beam geometric object or pattern a sufficient distance from where the laser light beam geometric object or pattern was previously applied to the retina to preclude thermal tissue damage.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 27, 2015
From: LUTTRULL, JEFFREY K.; MARGOLIS, BENJAMIN W. L.; CHANG, DAVID B.
To: OJAI RETINAL TECHNOLOGY, LLC
Reel/Frame 036891/0031 →
Continuity (4)
Continuation In Part 14607959 · Jan 28, 2015
Continuation In Part 13798523 · Mar 13, 2013
Continuation In Part 13481124 · May 25, 2012
Related Publication 20160058617A1 · Mar 3, 2016