IP Library Granted Patent US 10,952,468
Granted Patent B2
US 10,952,468 · App. 14/925,961 · Granted Mar 23, 2021

Nicotine salt formulations for aerosol devices and methods thereof

Inventors: Adam Bowen (San Francisco, CA); Chenyue Xing (San Francisco, CA)
Assignee: JUUL LABS, INC.
A24F47/008A24B15/16A24B15/167A61K9/007A61K9/12A61K31/465A61K31/60A61K47/10
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Quick Facts
Patent No.
US 10,952,468
App. No.
14/925,961
Granted
Mar 23, 2021
Kind
B2
Abstract

A nicotine salt liquid formulation for generating an inhalable aerosol in an electronic cigarette comprising nicotine salt that forms about 0.5% to about 20% nicotine is provide.

Claims (38)

1. An electronic cigarette comprising an electronic cigarette cartridge, the electronic cigarette cartridge comprising:

a nicotine salt liquid formulation for generating an inhalable aerosol upon heating in the electronic cigarette, the nicotine salt liquid formulation comprising a nicotine salt in a liquid carrier, wherein the nicotine salt comprises a salt of nicotine and benzoic acid in a liquid carrier, wherein

(a) the nicotine salt in the nicotine salt liquid formulation is present in an amount that forms from about 3% (w/w) to about 15% (w/w) nicotine in the inhalable aerosol;

(b) the liquid carrier comprises glycerol and propylene glycol; and

(c) the molar ratio of benzoic acid to nicotine in the nicotine salt liquid formulation is about 1:1.

2. The electronic cigarette of claim 1 , wherein the nicotine salt is present in an amount that forms about 4% (w/w) to about 12% (w/w) nicotine in the inhalable aerosol.

3. The method of claim 2 , wherein the nicotine salt is present in an amount that forms about 4% (w/w) nicotine in the inhalable aerosol.

4. The electronic cigarette of claim 1 , wherein the nicotine salt liquid formulation further comprises a flavorant.

5. The electronic cigarette of claim 1 , wherein the electronic cigarette cartridge is configured to serve as a mouthpiece and a reservoir that holds the nicotine salt liquid formulation.

6. The electronic cigarette of claim 1 , wherein the nicotine salt liquid formulation consists essentially of the nicotine, the liquid carrier, and the benzoic acid.

7. The electronic cigarette of claim 1 , the electronic cigarette further comprising a battery.

8. A method of providing nicotine to a user, the method comprising:

(i) heating a nicotine salt liquid formulation in an electronic cigarette to produce an inhalable aerosol, wherein the nicotine salt liquid formulation comprises a nicotine salt in a liquid carrier, wherein the nicotine salt comprises a salt of nicotine and benzoic acid, wherein

(a) the nicotine salt in the nicotine salt liquid formulation is present in an amount that forms from about 3% (w/w) to about 15% (w/w) nicotine in the inhalable aerosol;

(b) the liquid carrier comprises glycerol and propylene glycol; and

(c) the molar ratio of benzoic acid to nicotine in the nicotine salt liquid formulation is about 1:1; and

(ii) inhalation of the aerosol by the user.

9. The method of claim 8 , wherein the nicotine salt is present in an amount that forms about 4% (w/w) to about 12% (w/w) nicotine in the inhalable aerosol.

10. The method of claim 9 , wherein the nicotine salt is present in an amount that forms about 4% (w/w) nicotine in the inhalable aerosol.

11. The method of claim 8 , wherein the nicotine salt liquid formulation further comprises a flavorant.

12. The method of claim 8 , wherein the electronic cigarette comprises a cartridge, and the cartridge is configured to serve as a mouthpiece and a reservoir that holds the nicotine salt liquid formulation.

13. The method of claim 8 , wherein the nicotine salt liquid formulation consists essentially of the nicotine, the liquid carrier, and the benzoic acid.

14. An electronic cigarette comprising an electronic cigarette cartridge, the electronic cigarette cartridge comprising:

a nicotine salt liquid formulation for generating an inhalable aerosol upon heating in the electronic cigarette, the nicotine salt liquid formulation comprising a nicotine salt in a liquid carrier, wherein the nicotine salt comprises a salt of nicotine and benzoic acid, wherein

(a) the nicotine salt in the nicotine salt liquid formulation is present in an amount that forms from about 3% (w/w) to about 15% (w/w) nicotine in the inhalable aerosol;

(b) the liquid carrier comprises glycerol and propylene glycol;

(c) the molar ratio of benzoic acid to nicotine in the nicotine salt liquid formulation is about 1:1;

(d) the nicotine salt liquid formulation comprises a flavorant; and

(e) the electronic cigarette cartridge is configured to serve as a mouthpiece and a reservoir that holds the nicotine salt liquid formulation.

15. A method of vaporizing a nicotine salt liquid formulation, the method comprising heating the nicotine salt liquid formulation using an electronic cigarette to provide an inhalable aerosol, wherein the nicotine salt liquid formulation comprises a nicotine salt in a liquid carrier, wherein the nicotine salt comprises a salt of nicotine and benzoic acid, wherein

(a) the nicotine salt in the nicotine salt liquid formulation is present in an amount that forms from about 3% (w/w) to about 15% (w/w) nicotine in the inhalable aerosol;

(b) the liquid carrier comprises glycerol and propylene glycol; and

(c) the molar ratio of benzoic acid to nicotine in the nicotine salt liquid formulation is about 1:1.

16. The method of claim 15 , wherein the nicotine salt is present in an amount that forms about 4% (w/w) to about 12% (w/w) nicotine in the inhalable aerosol.

17. The method of claim 16 , wherein the nicotine salt is present in an amount that forms about 4% (w/w) nicotine in the inhalable aerosol.

18. The method of claim 15 , wherein the nicotine salt liquid formulation further comprises a flavorant.

19. The method of claim 15 , wherein the electronic cigarette comprises a cartridge, and the cartridge is configured to serve as a mouthpiece and a reservoir that holds the nicotine salt liquid formulation.

20. The method of claim 15 , wherein the nicotine salt liquid formulation consists essentially of the nicotine, the liquid carrier, and the benzoic acid.

Assignments (15)
RELEASE OF SECURITY INTEREST Recorded Oct 17, 2024
From: ALTER DOMUS (US) LLC
To: JUUL LABS, INC.; VMR PRODUCTS LLC; ENVENIO INC.
Reel/Frame 069185/0228 →
SECURITY INTEREST Recorded Jul 11, 2023
From: JUUL LABS, INC.; VMR PRODUCTS LLC; ENVENIO INC.
To: ALTER DOMUS (US) LLC
Reel/Frame 064252/0225 →
CORRECTIVE ASSIGNMENT TO CORRECT THE THE ASSIGNEE ADDRESS PREVIOUSLY RECORDED AT REEL: 062114 FRAME: 0196. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT. Recorded Dec 23, 2022
From: JUUL LABS, INC.
To: JLI NATIONAL SETTLEMENT TRUST
Reel/Frame 062214/0142 →
SECURITY INTEREST Recorded Dec 10, 2022
From: JUUL LABS, INC.
To: JLI NATIONAL SETTLEMENT TRUST
Reel/Frame 062114/0195 →
RELEASE OF SECURITY INTEREST Recorded Oct 1, 2022
From: CORTLAND CAPITAL MARKET SERVICES LLC
To: JUUL LABS, INC.
Reel/Frame 061587/0947 →
SECURITY INTEREST Recorded Sep 30, 2022
From: JUUL LABS, INC.
To: ALTER DOMUS (US) LLC
Reel/Frame 061578/0865 →
RELEASE OF SECURITY INTEREST Recorded Jun 28, 2022
From: MUFG UNION BANK, N.A.
To: JUUL LABS, INC.
Reel/Frame 060446/0261 →
SECURITY INTEREST Recorded Aug 2, 2019
From: JUUL LABS, INC.
To: CORTLAND CAPITAL MARKET SERVICES LLC
Reel/Frame 049948/0881 →
PATENT SECURITY AGREEMENT Recorded Apr 26, 2019
From: JUUL LABS, INC.
To: MUFG UNION BANK, N.A.
Reel/Frame 049013/0519 →
TERMINATION OF PATENT SECURITY AGREEMENT Recorded Apr 26, 2019
From: MUFG UNION BANK, N.A
To: JUUL LABS, INC.
Reel/Frame 049013/0397 →
CORRECTIVE ASSIGNMENT TO CORRECT THE ASSIGNOR EXECUTION DATE PREVIOUSLY RECORDED AT REEL: 043544 FRAME: 0004. ASSIGNOR(S) HEREBY CONFIRMS THE CHANGE OF NAME. Recorded Aug 6, 2018
From: PAX LABS, INC.
To: JUUL LABS, INC.
Reel/Frame 046732/0847 →
PATENT SECURITY AGREEMENT Recorded Apr 3, 2018
From: JUUL LABS, INC
To: MUFG UNION BANK, N.A.
Reel/Frame 045832/0328 →
CHANGE OF NAME Recorded Aug 14, 2017
From: PAX LABS, INC.
To: JUUL LABS, INC.
Reel/Frame 043544/0004 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 15, 2016
From: BOWEN, ADAM; XING, CHENYUE
To: PLOOM, INC.
Reel/Frame 037990/0840 →
CHANGE OF NAME Recorded Mar 15, 2016
From: PLOOM, INC.
To: PAX LABS, INC.
Reel/Frame 037990/0859 →
Continuity (4)
Continuation 14271071 · May 6, 2014
Provisional Application 61912507 · Dec 5, 2013
Provisional Application 61820128 · May 6, 2013
Related Publication 20160044967A1 · Feb 18, 2016
Cited By (1)
US 12,576,223