IP Library Granted Patent US 10,426,940
Granted Patent B2
US 10,426,940 · App. 14/940,889 · Granted Oct 1, 2019

Intraosseous infusion ports and methods of use

Inventors: Lishan Aklog (New York, NY); Brian J. deGuzman (Paradise Valley, AZ); Mark J. Orphanos (Foxboro, MA)
Assignee: PAVmed Inc.
A61M39/02A61M1/3655A61M2039/0205A61M2039/025A61M2039/027A61M2039/0258A61M2039/0261
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Quick Facts
Patent No.
US 10,426,940
App. No.
14/940,889
Granted
Oct 1, 2019
Kind
B2
Abstract

Example embodiments are related to intraosseous infusion port (IOP) devices to provide access to bone marrow cavities. The IOP device according to example embodiments may comprise a proximal portion with a hollow chamber extending through the proximal portion, the hollow chamber having a proximal inlet for receiving an insertion device. The IOP device may also include an anchor portion positioned distally to the proximal portion, the anchor portion may be configured for anchoring the infusion port device in a bone, and an open-ended channel extending through the anchor portion, the channel being in fluid communication with the hollow chamber, such that, when the infusion port is implanted into a bone, the channel and the hollow chamber create a substantially straight pathway terminating at an opening at its distal end for insertion of the insertion device towards the bone marrow.

Claims (29)

1. An infusion system comprising:

a chamber having an inlet configured for subcutaneous placement and for receiving an insertion device, a penetrable septum for sealing off the inlet, and an outlet opposing and orientated in a same direction as the chamber inlet;

an anchor portion extending distally from the chamber, and configured for secured placement in a bone;

a substantially flat surface substantially perpendicular to the anchor portion, at a junction between the chamber and the anchor portion, to limit a depth of penetration into the bone by the anchor portion; and

an open-ended channel extending through the anchor portion, the channel being in fluid communication with the outlet of the chamber, and providing a substantially straight pathway from the inlet to the outlet that terminates at an opening at a distal end of the anchor to allow the insertion device to exit from the channel to be directed towards and reach bone marrow, the opening being in axial alignment with the outlet,

wherein the chamber includes sloped walls configured for guiding an insertion device into the open-ended channel of the anchor portion.

2. The infusion system of claim 1 , wherein the penetrable septum for sealing off the inlet is configured to allow the insertion device to pass through the penetrable septum and access the chamber while maintaining the seal.

3. The infusion system of claim 1 , wherein the chamber includes one of a substantially straight channel and a reservoir shaped cavity.

4. The infusion system of claim 1 , wherein the chamber is a reservoir for holding substances.

5. The infusion system of claim 1 , wherein the anchor portion further includes a threaded surface for anchoring the infusion system into the bone.

6. The infusion system of claim 1 , wherein the sloped walls of the chamber are concave shaped or funnel shaped.

7. The infusion system of claim 6 , wherein the chamber has an upper diameter range from 5 millimeters to 15 millimeters, and a lower diameter range from 3 millimeters to 8 millimeters.

8. The infusion system of claim 6 , wherein the sloped walls have a slope range from 30 degrees to 60 degrees.

9. The infusion system of claim 1 , further including a magnetic ring positioned about the inlet of the chamber.

10. The infusion system of claim 9 , wherein the magnetic ring is configured for guiding an insertion device into the open-ended channel.

11. The infusion system of claim 1 , wherein the substantially flat surface is a retaining lip for coupling the chamber to the anchor portion.

12. An infusion system comprising:

a chamber having an inlet configured for subcutaneous placement and for receiving an insertion device, a penetrable septum for sealing off the inlet, and an outlet in axial alignment with the inlet;

an anchor portion extending distally from the chamber, and configured for secured placement in a bone, the anchor portion further includes a threaded surface for anchoring the infusion system into the bone and a guide path across the threaded surface for removing grinded bones during self-drilling;

a substantially flat surface substantially perpendicular to the anchor portion, at a junction between the chamber and the anchor portion, to limit a depth of penetration into the bone by the anchor portion; and

an open-ended channel extending through the anchor portion, the channel being in fluid communication with the outlet of the chamber, and providing a substantially straight pathway from the inlet to the outlet that terminates at an opening at a distal end of the anchor to allow the insertion device to exit from the channel to be directed towards and reach the bone marrow, the opening being in axial alignment with the outlet.

13. The infusion system of claim 12 , wherein the chamber is configured to be placed at the subcutaneous location under skin and is accessible through the skin.

14. The infusion system of claim 12 , wherein the anchor portion further comprises a retaining lip for coupling the chamber to the anchor portion and limiting a depth of penetration into bone marrow by the anchor portion.

15. The infusion system of claim 12 , wherein the chamber includes sloped walls.

16. The infusion system of claim 15 , wherein the sloped walls are configured for guiding an insertion device into the open-ended channel.

17. An infusion system comprising:

a chamber having a penetrable septum configured for subcutaneous placement and for receiving an insertion device, an outlet opposing and orientated in a same direction as an inlet of the chamber, and sloped walls between the inlet and the outlet for guiding an insertion device towards the outlet;

an anchor portion having a channel extending along its length and terminating in an opening, the channel being in fluid communication with the outlet of the chamber, and providing a substantially straight pathway to allow the insertion device to exit from the channel to be directed towards and reach bone marrow, the opening being in axial alignment with the outlet; and

a substantially flat surface substantially perpendicular to the anchor portion, at a junction between the chamber and the anchor portion, to limit a depth of penetration into the bone by the anchor portion.

Assignments (6)
SECURITY INTEREST Recorded Apr 6, 2022
From: PAVMED INC.; VERIS HEALTH INC.
To: ALTO OPPORTUNITY MASTER FUND, SPC - SEGREGATED MASTER PORTFOLIO B
Reel/Frame 059620/0086 →
SECURITY INTEREST Recorded Aug 14, 2020
From: PAVMED INC.
To: ALTO OPPORTUNITY MASTER FUND, SPC - SEGREGATED MASTER PORTFOLIO B
Reel/Frame 053497/0946 →
SECURITY INTEREST Recorded Nov 27, 2019
From: PAVMED INC.
To: ALTO OPPORTUNITY MASTER FUND, SPC - SEGREGATED MASTER PORTFOLIO B
Reel/Frame 051130/0512 →
SECURITY INTEREST Recorded Jan 3, 2019
From: PAVMED INC.
To: ALTO OPPORTUNITY MASTER FUND, SPC - SEGREGATED MASTER PORTFOLIO B
Reel/Frame 047894/0826 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 11, 2017
From: AKLOG, LISHAN; DEGUZMAN, BRIAN J.; ORPHANOS, MARK J.
To: PAVMED INC.
Reel/Frame 043837/0851 →
SECURITY INTEREST Recorded Jul 11, 2017
From: PAVMED INC.; PAVMED SPARCC INC.; PAVMED SUBSIDIARY CORP.
To: SCOPIA HOLDINGS LLC
Reel/Frame 042978/0607 →
Cited By (4)
US 12,551,236 US 12,599,405 US 12,653,575 US 12,702,441