IP Library › Granted Patent US 10,017,519
Granted Patent B2
US 10,017,519 · App. 14/953,392 · Granted Jul 10, 2018

Alpha-hydroxy carboxylic acid and derivatives and other GRAS based prodrugs of oxycodone and uses thereof

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Quick Facts
Patent No.
US 10,017,519
App. No.
14/953,392
Granted
Jul 10, 2018
Kind
B2
Abstract

The invention describes pharmaceutical compounds and compositions comprised of a ligand attached to the opioid oxycodone, in a manner that substantially decreases or deters the potential for opioid abuse, addiction, illicit and illegal use, and overdose. When delivered at the proper dosage, the pharmaceutical composition provides therapeutic activity similar to that of the parent active agent.

Claims (6)

1. An oxycodone prodrug compound represented by any one of

2. A pharmaceutical composition comprising one or more of the oxycodone prodrug compounds according to claim 1 and one or more pharmaceutically acceptable excipients.

3. An oral pharmaceutical composition comprising one or more of the the oxycodone prodrug compounds according to claim 1 and one or more pharmaceutically acceptable excipients.

4. The pharmaceutical composition according to claim 3 , wherein the compound is a pharmaceutically acceptable salt form.

5. A method of treating pain comprising orally administering the composition according to claim 3 to a patient.

6. The pharmaceutical composition according to claim 2 , wherein the compound is a pharmaceutically acceptable salt form.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 11, 2017
From: THOTTATHIL, JOHN K.
To: 3ST RESEARCH LLC
Reel/Frame 042969/0703 →