Two-dimensional needle array device and method of use
View Patent ↗In one aspect, the present disclosure relates to a device for obtaining biological tissue. In some embodiments, the device can include a first row of a plurality of hollow tubes; a second row of a plurality of hollow tubes, adjacent the first row of hollow tubes; a third row of a plurality of hollow tubes, adjacent the second row of hollow tubes, the first, second and third rows forming an array of hollow tubes; wherein each hollow tube can include at least one point at the distal end of the hollow tube, the plurality of rows forming a two dimensional array of hollow tubes; wherein an inner diameter of the at least one tube is less than about 1 mm, the distal end of each of the hollow tubes is configured to be inserted into a biological tissue donor site to remove a portion of tissue therefrom when each of the hollow tubes is withdrawn from the donor site.
1. A device for obtaining biological tissue comprising;
an array of hollow tubes, the array comprising
a first row of a plurality of hollow tubes;
a second row of a plurality of hollow tubes, adjacent the first row of hollow tubes;
a third row of a plurality of hollow tubes, adjacent the second row of hollow tubes, the first, second and third rows forming an array of hollow tubes;
wherein each hollow tube comprises two points at the distal end of the hollow tube, the plurality of rows forming a two dimensional array of hollow tubes;
wherein the two points are formed by a first bevel on a first external side of an outer surface of the hollow tube and a second bevel on a second external side of an outer surface of the tube opposing the first side of the hollow tube;
the first bevel having at least two angle sections including a first shallow angle section to form a first narrow heel and the second bevel having at least two angle sections including a second shallow angle section to form a second narrow heel;
the array comprising a circle having an area of about one square inch;
wherein an inner diameter of each hollow tube is less than about 1 mm, the distal end of each of the hollow tubes is configured to be inserted into a biological tissue donor site to remove a portion of tissue therefrom when each of the hollow tubes is withdrawn from the donor site;
wherein the array comprises a sufficient number of hollow tubes to withdraw about 0.1 square inches of tissue from the donor site with a single insertion of the array;
a first solenoid, wherein first the solenoid actuates at least a first row of hollow tubes to insert at least the first row of hollow tubes into the biological tissue donor site.
2. The device of claim 1 , wherein the donor site comprises an area of about one square inch.
3. The device of claim 1 wherein the array of hollow tubes comprises about 300 hollow tubes.
4. The device of claim 1 comprising: a plurality of pins, each of the pins provided within a central lumen of each of the hollow tubes.
5. The device of claim 1 , comprising a stop to limit the depth of insertion into biological tissue of each of the hollow tubes in the array of hollow tubes.
6. The device of claim 1 , comprising a second solenoid, wherein the second solenoid actuates in a direction opposite the first solenoid.
7. The device of claim 1 , comprising a force sensor, wherein the force sensor senses the force with which the device is applied to the biological tissue donor site.
8. The device of claim 1 , wherein the first narrow heel comprises less than about 10% of the inner diameter of the hollow tube and the second narrow heel comprises less than about 10% of the inner diameter of the hollow tube.
9. The device of claim 1 , wherein the hollow tube has an inner diameter of less than about 0.8 mm.
10. The device of claim 1 , wherein the biological tissue comprises skin tissue and adipose tissue.