IP Library Granted Patent US 9,888,971
Granted Patent B2
US 9,888,971 · App. 14/987,107 · Granted Feb 13, 2018

Method and system for image processing to determine patient-specific blood flow characteristics

View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 9,888,971
App. No.
14/987,107
Granted
Feb 13, 2018
Kind
B2
Abstract

Embodiments include a system for determining cardiovascular information for a patient. The system may include at least one computer system configured to receive patient-specific data regarding a geometry of the patient's heart, and create a three-dimensional model representing at least a portion of the patient's heart based on the patient-specific data. The at least one computer system may be further configured to create a physics-based model relating to a blood flow characteristic of the patient's heart and determine a fractional flow reserve within the patient's heart based on the three-dimensional model and the physics-based model.

Claims (25)

1. A system for medical image processing, the system comprising:

a data storage device storing instructions for medical image processing; and

a processor configured to execute the instructions to perform a method including:

receiving one or more non-invasively produced images of at least a blood vessel of a patient;

segmenting the images to identify an ischemic region of interest of the blood vessel and generating a three-dimensional geometric model of the identified ischemic region of interest of the blood vessel;

identifying a vessel region of interest in the identified ischemic region of interest;

identifying a stenosis in the vessel region of interest based on a pressure index computed using a first simulation of blood flow through the geometric model of the blood vessel;

determining a connection position to connect a bypass vessel that diverts blood flow around the identified stenosis, wherein the connection position is determined using a subsequent simulation of blood flow; and

displaying the determined connection position on a display.

2. The system of claim 1 , wherein the determining step comprises determining the connection position using the pressure index in the vessel of interest.

3. The system of claim 2 , wherein the determining step comprises determining a drop level of the pressure index.

4. The system of claim 3 , wherein the determining step comprises determining the connection position using a measurement of the interior of the vessel of interest.

5. The system of claim 3 , wherein the determining step comprises determining an elasticity of the vessel of interest.

6. The system of claim 2 , wherein the determining step comprises determining the connection position using a measurement of the interior of the vessel of interest.

7. The system of claim 1 , wherein the displaying step comprises displaying, on the display, a first graph representing the pressure index corresponding to the connection.

8. The system of claim 7 , wherein the displaying step comprises displaying the first graph with an image in which the connection position is visualized.

9. The system of claim 1 , wherein the determining step comprises calculating a degree of fitness when the bypass vessel is connected to a predetermined portion of the blood vessel, and wherein the displaying step comprises displaying a distribution of the degree of fitness at the predetermined portion on the display.

10. The system of claim 1 , wherein the pressure index comprises a myocardial fractional flow reserve.

11. A method of processing medical images, comprising:

receiving one or more non-invasively produced images of at least a blood vessel of a patient;

segmenting the images to identify an ischemic region of interest of the blood vessel and generating a three-dimensional geometric model in a plurality of phases region of the identified ischemic region of interest of the blood vessel;

identifying a vessel region of interest in the identified ischemic region of interest;

identifying a stenosis in the vessel region of interest based on a pressure index computed using a first simulation of blood flow through the geometric model of the blood vessel;

determining a connection position to connect a bypass vessel that diverts blood flow around the identified stenosis, wherein the connection position is determined using a subsequent simulation of blood flow; and

displaying the determined connection position on a display.

Assignments (5)
RELEASE OF SECURITY INTEREST Recorded Sep 11, 2025
From: HAYFIN SERVICES LLP
To: HEARTFLOW, INC.
Reel/Frame 072876/0775 →
RELEASE OF SECURITY INTEREST Recorded Jun 21, 2024
From: HAYFIN SERVICES LLP
To: HEARTFLOW, INC.
Reel/Frame 067801/0032 →
SECURITY INTEREST Recorded Jun 18, 2024
From: HEARTFLOW, INC.
To: HAYFIN SERVICES LLP
Reel/Frame 067775/0966 →
SECURITY INTEREST Recorded Jan 20, 2021
From: HEARTFLOW, INC.
To: HAYFIN SERVICES LLP
Reel/Frame 055037/0890 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 8, 2016
From: TAYLOR, CHARLES A.
To: HEARTFLOW, INC.
Reel/Frame 037437/0786 →