Multi-supplement compositions
This document provides dietary supplement compositions. For example, multi-supplement compositions having combinations of dietary supplement formulations useful for human or animal consumption are provided.
1. A multi-supplement composition comprising:
(a) a dietary supplement of a Supplement Formulation A comprising:
(i) from about 5 billion to about 15 billion cfu of a mixture of Lactobacillus acidophilus, Lactobacillus plantarum, Lactobacillus casei, Lactobacillus rhamnosus , and Bifidobacterium lactis,
(ii) a filler having a water activity less than 0.2, and
(iii)
fructooligosaccharides,
wherein said dietary supplement of Supplement Formulation A is in the form of a capsule that releases said Lactobacillus acidophilus, Lactobacillus plantarum, Lactobacillus casei, Lactobacillus rhamnosus , and Bifidobacterium lactis , within an intestine of a mammal following oral administration to said mammal;
(b) a dietary supplement of a Supplement Formulation B comprising:
(i) a fat-soluble antioxidant,
(ii) a phenolic compound, and
(iii) a water soluble antioxidant;
(c) a dietary supplement of a Supplement Formulation C comprising:
(i) an iridoid,
(ii) a ginger component,
(iii) an anthocyanin, and
(iv) at least one agent selected from the group consisting of a coumarin, a curcuminoid, and a green tea extract;
(d) a dietary supplement of a Supplement Formulation E comprising:
(i) a grape seed extract, and
(ii) an enzyme selected from the group consisting of a fungal protease, an acid stable protease, and bromelain; and
(e) a dietary supplement of a Supplement Formulation F consisting essentially of one or more mineral-amino acid compound/polysaccharide complexes, wherein each of said one or more mineral-amino acid/polysaccharide complexes comprises one or more mineral-amino acid compounds conjugated to one or more polysaccharides.
2. The composition of claim 1 , further comprising a dietary supplement of a Supplement Formulation G comprising:
(i) huperzine A,
(ii) acetyl-L-carnitine,
(iii) a Bacopa monnieri extract, and
(iv) curcumin.
3. The composition of claim 1 , further comprising a dietary supplement of a Supplement Formulation H comprising phosphatidylserine.
4. The composition of claim 3 , wherein Supplement Formulation H further comprises:
(i) DHA,
(ii) EPA,
(iii) an antioxidant, and
(iv) Ginkgo biloba.
5. The composition of claim 1 , further comprising a dietary supplement of a Supplement Formulation D comprising fish oil.
6. The composition of claim 1 , further comprising a dietary supplement of a Supplement Formulation I comprising Vitamin K 2 and Vitamin D 3 .
7. The composition of claim 1 , further comprising a dietary supplement of a Supplement Formulation J comprising CoQ10, a tocotrienol, and alpha-lipoic acid.
8. The composition of claim 1 , further comprising a dietary supplement of a Supplement Formulation K comprising:
(i) a sterol compound, and
(ii) omega 3 fatty acids.
9. The composition of claim 1 , further comprising a dietary supplement of a Supplement Formulation L comprising calcium.
10. The composition of claim 1 , further comprising a dietary supplement of a Supplement Formulation M that comprises glucosamine hydrochloride.
11. The composition of claim 10 , wherein Supplement Formulation M further comprises chondroitin sulfate and methyl sulfonyl methane.
12. The composition of claim 1 , further comprising a dietary supplement of a Supplement Formulation N comprising a green coffee bean extract, a green tea phytosome, a green tea extract, and a red pepper extract.
13. The composition of claim 1 , wherein the mineral-amino acid compound/polysaccharide complex is prepared by heating a composition comprising water, one or more mineral-amino acid compounds, and one or more polysaccharides at a temperature from about 100° F. to about 180° F.
14. The composition of claim 1 , wherein the mineral-amino acid compound/polysaccharide complex has a ratio of mineral-amino acid compound to polysaccharide of from about 5:1 to about 1:1.
15. The composition of claim 5 , wherein the composition results in an average reduction of heart rate of at least 5 bpm in a subject after the subject performs an exercise within one hour of administration to the subject as compared to a heart rate of the subject after performing the exercise without administration of the composition.
16. The composition of claim 5 , wherein the composition results in at least a 21% reduction in hs-CRP in a subject after administration of the composition to the subject for at least 12 weeks.
17. The composition of claim 5 , wherein the composition results in an average reduction in resting ROS during rest of at least 22% after administration of the composition to the subject for at least 6 weeks.
18. The composition of claim 5 , wherein the composition results in an average reduction in ROS during exercise of at least 25% after administration of the composition to the subject for at least 6 weeks.
19. A multi-supplement composition comprising:
a dietary supplement of a Supplement Formulation A comprising:
(i) from about 5 billion to about 15 billion cfu of a mixture of Lactobacillus acidophilus, Lactobacillus plantarum, Lactobacillus casei, Lactobacillus rhamnosus , and Bifidobacterium lactis,
(ii) a filler having a water activity less than 0.2, and
(iii)
fructooligosaccharides,
wherein said dietary supplement of Supplement Formulation A is in the form of a capsule that releases said Lactobacillus acidophilus, Lactobacillus plantarum, Lactobacillus casei, Lactobacillus rhamnosus , and Bifidobacterium lactis , within an intestine of a mammal following oral administration to said mammal;
a dietary supplement of a Supplement Formulation B comprising:
150-600 mg Vitamin C,
25-100 mg α-tocopherol,
0.05-0.2 mg α-carotene,
1-4 mg β-carotene,
0.1-0.4 mg criptoxanthin,
0.05-0.2 mg zeaxanthin,
0.05-0.2 mg lutein,
1.5-6 mg lycopene,
3.5-13 mg β-tocopherol,
12-50 mg δ-tocopherol,
50-200 mg γ-tocopherol,
75-300 mg olive fruit extract, and
12-50 mg grape seed extract;
a dietary supplement of a Supplement Formulation C comprising 100-1000 mg of a combination of Devil's Claw Extract, Ginger Root Extract, Chokeberry Extract, Green Tea Leaf Extract, Angelica gigas Root Extract, and Turmeric Root Extract;
a dietary supplement of a Supplement Formulation D comprising 1000-5000 mg fish oil concentrate;
a dietary supplement of a Supplement Formulation E comprising:
100-1000 HUT fungal protease,
20-200 mg quercetin,
0.1-200 mg Bilberry extract, and
0.1-100 mg Ginkgo biloba Leaf Extract; and
a dietary supplement of a Supplement Formulation F comprising:
200-1000 mg calcium, at least a portion of which is present as calcium amino acid oligofructose complex,
0-18 mg iron, at least a portion of which is present as iron amino acid oligofructose complex,
100-300 mcg iodine, at least a portion of which is present as iodine amino acid oligofructose complex,
100-400 mg magnesium, at least a portion of which is present as magnesium amino acid oligofructose complex,
5-30 mg zinc, at least a portion of which is present as zinc amino acid oligofructose complex,
35-150 mcg selenium, at least a portion of which is present as selenium amino acid oligofructose complex,
1-5 mg copper, at least a portion of which is present as copper amino acid oligofructose complex,
1-5 mg manganese, at least a portion of which is present as manganese amino acid oligofructose complex,
60-360 mcg chromium, at least a portion of which is present as chromium amino acid oligofructose complex,
50-150 mcg molybdenum, at least a portion of which is present as molybdenum amino acid oligofructose complex, and
0-300 mcg boron, at least a portion of which is present as boron amino acid oligofructose complex.
20. A multi-supplement composition comprising:
a dietary supplement of a Supplement Formulation A comprising:
(i) from about 5 billion to about 15 billion cfu of a mixture of Lactobacillus acidophilus, Lactobacillus plantarum, Lactobacillus casei, Lactobacillus rhamnosus , and Bifidobacterium lactis,
(ii) a filler having a water activity less than 0.2, and
(iii)
fructooligosaccharides,
wherein said dietary supplement of Supplement Formulation A is in the form of a capsule that releases said Lactobacillus acidophilus, Lactobacillus plantarum, Lactobacillus casei, Lactobacillus rhamnosus , and Bifidobacterium lactis , within an intestine of a mammal following oral administration to said mammal;
a dietary supplement of a Supplement Formulation B comprising:
2500 IU Vitamin A,
300 mg Vitamin C,
60 IU Vitamin E,
1000 mcg carotenoids,
32 mg of a combination of β-tocopherol, δ-tocopherol, and γ-tocopherol,
150 mg olive fruit extract, and
25 mg grape seed extract;
a dietary supplement of a Supplement Formulation C comprising 605 mg of a combination of Devil's Claw Extract, Ginger Root Extract, Chokeberry Extract, Green Tea Leaf Extract, Angelica Gigas Root Extract, and Turmeric Root Extract;
a dietary supplement of a Supplement Formulation D comprising 2000 mg fish oil concentrate;
a dietary supplement of a Supplement Formulation E comprising:
330 mg of a combination of grape seed and grape skin extracts, and
60 mg of a combination of bromelain, fungal protease, quercetin, Bilberry extract, and Ginkgo biloba Leaf Extract; and
a dietary supplement of a Supplement Formulation F comprising:
250 mg calcium, at least a portion of which is present as calcium amino acid oligofructose complex,
150 mcg iodine, at least a portion of which is present as iodine amino acid oligofructose complex,
200 mg magnesium, at least a portion of which is present as magnesium amino acid oligofructose complex,
15 mg zinc, at least a portion of which is present as zinc amino acid oligofructose complex,
105 mcg selenium, at least a portion of which is present as selenium amino acid oligofructose complex,
3 mg copper, at least a portion of which is present as copper amino acid oligofructose complex,
120-180 mcg chromium, at least a portion of which is present as chromium amino acid oligofructose complex,
75-90 mcg molybdenum, at least a portion of which is present as molybdenum amino acid oligofructose complex, and
150 mcg boron, at least a portion of which is present as boron amino acid oligofructose complex.
21. The composition of claim 1 , wherein said Supplement Formulation A has a water activity of about 0.1 to about 0.2.
22. The composition of claim 1 , wherein said Supplement Formulation A comprises about 3.5 wt % to about 5.0 wt % fructooligosaccharides.
23. The composition of claim 1 , wherein said Supplement Formulation A comprises about 1 mg and about 50 mg fructooligosaccharides per every gram of the composition.
24. The composition of claim 1 , wherein said dietary supplement of Supplement Formulation A has a water activity of about 0.125 to about 0.171.