IP Library Granted Patent US 10,806,419
Granted Patent B2
US 10,806,419 · App. 14/992,550 · Granted Oct 20, 2020

X-ray CT apparatus, X-ray CT system, and injector

Inventors: Masaharu Tsuyuki (Nasushiobara, JP); Tatsuo Maeda (Nasushiobara, JP)
Assignee: Canon Medical Systems Corporation
A61B6/481A61B6/032A61B6/4241A61B6/482A61B6/486A61B6/5205A61B6/542
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Quick Facts
Patent No.
US 10,806,419
App. No.
14/992,550
Granted
Oct 20, 2020
Kind
B2
Abstract

According to one embodiment, an X-ray CT apparatus includes a calculator, a transmitter, a data acquisition unit, and a processor. The calculator calculates a difference between imaging time phases of a first contrast agent and a second contrast agent. The transmitter sends information on the difference between the imaging time phases to an injector. The injector injects the first contrast agent and the second contrast agent into the subject at different timings based on the information. The data acquisition unit scans a subject with X-rays at a predetermined imaging timing to acquire detection data corresponding to different X-ray energies. The processor analyzes the detection data acquired at the predetermined imaging timing to generate a plurality of images corresponding to the imaging time phases.

Claims (35)

1. An X-ray CT apparatus, comprising:

processing circuitry configured to

calculate a difference in injection timing between a first contrast agent and a second contrast agent to be injected into a subject, wherein the difference in injection timing is calculated depending on a type of each of the first contrast agent and the second contrast agent, injection conditions of each of the first contrast agent and the second contrast agent, an organ to be scanned, and cardiac output;

send information on the calculated difference in injection timing to an injector;

control a scan controller to scan the subject with X-rays at an imaging timing at which an imaging effect of the first contrast agent is appearing in an artery of the organ and an imaging effect of the second contrast agent is appearing in a tissue of the organ in an imaging target range at a same time to acquire detection data corresponding to different X-ray energies, wherein the first contrast agent and the second contrast agent are injected into the subject by the injector at different injection timings based on the calculated difference in injection timing; and

analyze the acquired detection data acquired at the imaging timing to generate a first image representing the imaging effect of the first contrast agent and a second image representing the imaging effect of the second contrast agent.

2. The X-ray CT apparatus of claim 1 , wherein the processing circuitry is further configured to calculate the difference in injection timing based on X-ray detection data of the subject obtained in advance.

3. The X-ray CT apparatus of claim 1 , wherein the processing circuitry is further configured to obtain a value related to blood perfusion from a value based on a linear attenuation coefficient corresponding to an arterial segment in the first image and a value based on a linear attenuation coefficient corresponding to a tissue portion in the second image.

4. The X-ray CT apparatus of claim 3 , wherein an injection timing of the second contrast agent is set such that concentration of the second contrast agent is substantially maximum in the tissue portion in the second image at the imaging timing.

5. The X-ray CT apparatus of claim 1 , wherein the difference in injection timing is calculated based on information that indicates time-series changes of a CT value of the first contrast agent in an arterial segment and information that indicates time-series changes of a CT value of the second contrast agent in a tissue of the subject.

6. The X-ray CT apparatus of claim 1 , wherein an injection timing of the first contrast agent is set such that a concentration of the first contrast agent is substantially maximum in an arterial segment in the first image at the imaging timing.

7. The X-ray CT apparatus of claim 1 , wherein the processing circuitry is further configured to send at least one of the injection conditions or an injection order of the first contrast agent and the second contrast agent to the injector together with the information on the calculated difference in injection timing.

8. An X-ray CT system, comprising:

an injector configured to inject a contrast agent into a subject, and

an X-ray CT apparatus configured to perform X-ray imaging of the subject, the X-ray CT apparatus including processing circuitry configured to:

calculate a difference in injection timing between a first contrast agent and a second contrast agent to be injected into a subject, wherein the difference in injection timing is calculated depending on a type of each of the first contrast agent and the second contrast agent, injection conditions of each of the first contrast agent and the second contrast agent, an organ to be scanned, and cardiac output;

send information on the calculated difference in injection timing to the injector;

control a scan controller to scan the subject with X-rays at an imaging timing at which an imaging effect of the first contrast agent is appearing in an artery of the organ and an imaging effect of the second contrast agent is appearing in a tissue of the organ in an imaging target range at a same time to acquire detection data corresponding to different X-ray energies, wherein the first contrast agent and the second contrast agent have been injected into the subject by the injector at different injection timings based on the difference in injection timing; and

analyze the acquired detection data acquired at the imaging timing to generate a first image representing the imaging effect of the first contrast agent and a second image representing the imaging effect of the second contrast agent.

9. The X-ray CT system of claim 8 , wherein

the different injection timings correspond to the imaging timing, and

the imaging timing arrives after the different injection timings.

10. The X-ray CT apparatus of claim 1 , wherein the processing circuitry is further configured to calculate the difference in injection timing according to a target site included in the imaging target range.

11. The X-ray CT system of claim 8 , wherein the processing circuitry is further configured to calculate the difference in injection timing based on X-ray detection data of the subject obtained in advance.

12. The X-ray CT system of claim 8 , wherein the difference in injection timing is calculated based on information that indicates time-series changes of a CT value of the first contrast agent in an arterial segment and information that indicates time-series changes of a CT value of the second contrast agent in a tissue of the subject.

13. The X-ray CT system of claim 8 , wherein an injection timing of the first contrast agent is set such that a concentration of the first contrast agent is substantially maximum in an arterial segment in the first image at the imaging timing.

14. The X-ray CT system of claim 8 , wherein the processing circuitry is further configured to send at least one of the injection conditions or an injection order of the first contrast agent and the second contrast agent to the injector together with the information on the calculated difference in injection timing.

15. A method, comprising:

calculating a difference in injection timing between a first contrast agent and a second contrast agent to be injected into a subject by an injector, the difference in injection timing depending on a type of each of the first contrast agent and the second contrast agent, injection conditions of each of the first contrast agent and the second contrast agent, an organ to be scanned, and cardiac output;

scanning, using a X-ray CT scanner, the subject with X-rays at an imaging timing at which an imaging effect of the first contrast agent is appearing in an artery of the organ and an imaging effect of the second contrast agent is appearing in a tissue of the organ in an imaging target range at a same time to acquire detection data corresponding to different X-ray energies, wherein the first contrast agent and the second contrast agent are injected into the subject by the injector at different injection timings based on the difference in injection timing; and

analyzing the detection data acquired at the imaging timing to generate a first image representing the imaging effect of the first contrast agent and a second image representing the imaging effect of the second contrast agent.

16. The method of claim 15 , further comprising calculating the difference in injection timing based on X-ray detection data of the subject obtained in advance.

17. The method of claim 15 , wherein the difference in injection timing is calculated based on information that indicates time-series changes of a CT value of the first contrast agent in an arterial segment and information that indicates time-series changes of a CT value of the second contrast agent in a tissue of the subject.

18. The method of claim 15 , wherein an injection timing of the first contrast agent is set such that a concentration of the first contrast agent is substantially maximum in an arterial segment in the first image at the imaging timing.

19. The method of claim 15 , further comprising sending at least one of the injection conditions or an injection order of the first contrast agent and the second contrast agent to the injector together with the information on the calculated difference in injection timing.

Assignments (4)
CHANGE OF NAME Recorded Jul 26, 2019
From: TOSHIBA MEDICAL SYSTEMS CORPORATION
To: CANON MEDICAL SYSTEMS CORPORATION
Reel/Frame 049879/0342 →
CORRECTIVE ASSIGNMENT TO CORRECT THE SERIAL NUMBER FOR 14354812 WHICH WAS INCORRECTLY CITED AS 13354812 PREVIOUSLY RECORDED ON REEL 039099 FRAME 0626. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT. Recorded Aug 1, 2016
From: KABUSHIKI KAISHA TOSHIBA
To: TOSHIBA MEDICAL SYSTEMS CORPORATION
Reel/Frame 039609/0953 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 21, 2016
From: KABUSHIKI KAISHA TOSHIBA
To: TOSHIBA MEDICAL SYSTEMS CORPORATION
Reel/Frame 039099/0626 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 11, 2016
From: TSUYUKI, MASAHARU; MAEDA, TATSUO
To: KABUSHIKI KAISHA TOSHIBA; TOSHIBA MEDICAL SYSTEMS CORPORATION
Reel/Frame 037454/0655 →