IP Library › Granted Patent US 9,593,099
Granted Patent B2
US 9,593,099 · App. 14/994,710 · Granted Mar 14, 2017

Compounds and compositions as protein kinase inhibitors

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Quick Facts
Patent No.
US 9,593,099
App. No.
14/994,710
Granted
Mar 14, 2017
Kind
B2
Abstract

The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly diseases or disorders that involve abnormal activation of B-Raf.

Claims (3)

1. A compound of the formula:

(methyl N-[(2S)-1-({4-[3-(5-chloro-2-fluoro-3-methanesulfonamidophenyl)-1-(propan-2-yl)-1H-pyrazol-4-yl]pyrimidin-2-yl}amino)propan-2-yl]carbamate), or a pharmaceutically acceptable salt thereof.

2. The compound of claim 1 , which is methyl N-[(2S)-1-({4-[3-(5-chloro-2-fluoro-3-methanesulfonamidophenyl)-1-(propan-2-yl)-1H-pyrazol-4-yl]pyrimidin-2-yl}amino)propan-2-yl]carbamate.

Assignments (5)
MERGER Recorded Jul 13, 2016
From: IRM LLC
To: NOVARTIS INTERNATIONAL PHARMACEUTICAL LTD.
Reel/Frame 039145/0300 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 13, 2016
From: NOVARTIS INTERNATIONAL PHARMACEUTICAL LTD.
To: NOVARTIS AG
Reel/Frame 039145/0410 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 13, 2016
From: NOVARTIS AG
To: ARRAY BIOPHARMA, INC.
Reel/Frame 039146/0475 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 16, 2016
From: HUANG, SHENLIN; LIU, ZUOSHENG; TELLEW, JOHN; WAN, YONGQIN; WANG, XING; XIE, YONGPING
To: IRM LLC
Reel/Frame 038929/0921 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 16, 2016
From: JIN, XIANMING; POON, DANIEL
To: NOVARTIS AG
Reel/Frame 038929/0983 →