Hemostatic compositions, devices, and methods
View Patent ↗Compositions that include a clay such as kaolin dispersed in a liquid such as water may be useful for promoting the clotting of blood. The compositions may be in a liquid, gel, paste, foam, or another form. Uses may include treating a traumatic injury such as in injury caused by a bullet, an explosive, a blade etc., or an injury caused during a medical procedure such as surgery.
1. A hemostatic device comprising:
an absorbent material;
a composition comprising a clay hemostatic agent and hydroxypropylmethylcellulose;
wherein the clay hemostatic agent is kaolin;
wherein the composition is suspended in a liquid to form a suspension;
wherein the suspension is absorbed onto the absorbent material during preparation of the hemostatic device; and
wherein the clay hemostatic agent comprises about 10% or less of the weight of the suspension.
2. The hemostatic device of claim 1 , wherein the absorbent material is selected from the group consisting of a sponge, a cloth, and a gauze.
3. The hemostatic device of claim 1 , wherein the hemostatic device further comprises one or more of bentonite, montmorillonite, saponite, polygorskite or attapulgite, and sepiolite.
4. A hemostatic device comprising:
an absorbent material;
a composition comprising a clay hemostatic agent and a thickening agent selected from the group consisting of hydroxypropylmethylcellulose, methylcellulose, and hydroxypropylcellulose;
wherein the clay hemostatic agent is kaolin; and
wherein the composition is suspended in a liquid and absorbed onto the absorbent material during preparation of the hemostatic device.
5. The hemostatic device of claim 4 , wherein the absorbent material is selected from the group consisting of a sponge, a cloth, and a gauze.
6. The hemostatic device of claim 4 , wherein the hemostatic device further comprises one or more of bentonite, montmorillonite, saponite, polygorskite or attapulgite, and sepiolite.
7. The hemostatic device of claim 4 , wherein the thickening agent is a gelling agent.
8. The hemostatic device of claim 4 , wherein the thickening agent is hydroxypropylmethylcellulose.
9. A hemostatic device configured to halt the flow of blood from a bleeding wound, the hemostatic device comprising:
an absorbent gauze;
a hemostatic clay applied to the gauze such that the clay is configured to be dispensed onto a bleeding wound when the hemostatic device is applied to the bleeding wound;
a composition comprising hydroxypropylmethylcellulose applied to the gauze;
wherein the hemostatic clay comprises kaolin; and
wherein the gauze is not saturated with liquid such that the gauze is capable of absorbing blood when the hemostatic device is applied to a bleeding wound.
10. The hemostatic device of claim 9 , wherein the hemostatic device is dry.
11. The hemostatic device of claim 9 , wherein the hemostatic device is provided in a sterilized package.
12. The hemostatic device of claim 9 , wherein the hydroxypropylmethylcellulose acts as a thickening agent.