IP Library Granted Patent US 10,098,918
Granted Patent B2
US 10,098,918 · App. 15/008,154 · Granted Oct 16, 2018

Vaporized medicants and methods of use

Inventors: Alexander Chinhak Chong (St. Louis Park, MN); William P Bartkowski (Edina, MN); Marshall A Thompson (Camarillo, CA)
Assignee: CHONG CORPORATION
A61K36/296A61K9/007A61K31/475A61K31/485A61K31/7048A61K36/34A61K47/10A61K47/26A61K2236/00Y10S514/958
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Quick Facts
Patent No.
US 10,098,918
App. No.
15/008,154
Granted
Oct 16, 2018
Kind
B2
Abstract

A method and formulation for delivering a sexual aid, such as epimedium or yohimbe, in a vaporized state using low temperatures to vaporize the formulation. The formulation contains an inert non-reactive compound that lowers the heat of vaporization of the formulation, and the active compound. The formulation may optionally contain glycerin, alcohol, and/or water. Examples of inert non-reactive compounds that can sufficiently lower the heat of vaporization of the formulation include propylene glycol, vegetable glycerin and polysorbate. The formulation can be vaporized using a hand-held low temperature vaporizer or atomizer.

Claims (105)

1. A method for delivering medicants through inhalation, comprising:

a. acquiring a medicant solution suitable for vaporization at a low temperature, the medicant solution, comprising:

i. an excipient comprising propylene glycol present at approximately 1 percent to approximately 30 percent of the excipient, vegetable glycerin present at approximately 1 percent to approximately 30 percent of the excipient, polysorbate present at approximately 1 percent to approximately 30 percent of the excipient, water present at approximately 0.01 percent to approximately 30 percent of the excipient, and alcohol present at approximately 0.01 percent to approximately 30 percent of the excipient, and

ii. a sexual aid; and

b. vaporizing the medicant solution at the low temperature such that an effective serving of the sexual aid is provided to the user for inhalation, wherein the low temperature is from approximately 90 degrees C. to approximately 280 degrees C., wherein the step of vaporizing the medicant solution comprises using a low temperature vaporizer.

2. A method for delivering medicants through inhalation, comprising:

a. acquiring a medicant solution suitable for vaporization at a low temperature with a low temperature vaporizer having a heating element, the medicant solution, comprising:

i. an excipient comprising an inert non-reactive compound, and

ii. a sexual aid comprising epimedium; and

b. vaporizing the medicant solution at the low temperature such that an effective serving of the sexual aid is provided to the user for inhalation, wherein the heating element provides the low temperature from approximately 90 degrees C. to approximately 280 degrees C.

3. The method of claim 2 , wherein the step of vaporizing the medicant solution comprises using a low temperature vaporizer.

4. The method of claim 2 , wherein the inert non-reactive compound is polysorbate.

5. The method of claim 4 , wherein the polysorbate is present at a concentration of at least about 1 percent of the excipient.

6. The method of claim 4 , wherein the polysorbate is present at a concentration of at least about 10 percent of the excipient.

7. The method of claim 4 , wherein the polysorbate is present at a concentration of at least about 30 percent of the excipient.

8. The method of claim 4 , wherein the polysorbate is present at a concentration of at least about 70 percent of the excipient.

9. The method of claim 4 , wherein the polysorbate is present at a concentration of at least about 85 percent of the excipient.

10. The method of claim 4 , wherein the polysorbate comprises about 100 percent of the excipient.

11. The method of claim 4 , wherein the low temperature is about 90 degrees C. to about 200 degrees C.

12. The method of claim 4 , wherein the low temperature is about 90 degrees C. to about 180 degrees C.

13. The method of claim 4 , wherein the low temperature is about 90 degrees C. to about 160 degrees C.

14. The method of claim 4 , wherein the low temperature is about 90 degrees C. to about 150 degrees C.

15. The method of claim 4 , wherein the low temperature is about 90 degrees C. to about 140 degrees C.

16. The method of claim 4 , wherein the low temperature is about 90 degrees C. to about 120 degrees C.

17. The method of claim 2 , wherein the excipient comprises any one or more polysorbate compound selected from the group consisting of polysorbate 20, polysorbate 40, polysorbate 60, and polysorbate 80.

18. The method of claim 2 , wherein the inert non-reactive compound is propylene glycol.

19. The method of claim 18 , wherein the propylene glycol is present at a concentration of at least about 1 percent of the excipient.

20. The method of claim 18 , wherein the propylene glycol is present at a concentration of at least about 10 percent of the excipient.

21. The method of claim 18 , wherein the propylene glycol is present at a concentration of at least about 30 percent of the excipient.

22. The method of claim 18 , wherein the propylene glycol is present at a concentration of at least about 70 percent of the excipient.

23. The method of claim 18 , wherein the propylene glycol is present at a concentration of at least about 85 percent of the excipient.

24. The method of claim 18 , wherein the propylene glycol comprises 100 percent of the excipient.

25. The method of claim 18 , wherein the low temperature is from approximately 90 degrees C. to approximately 250 degrees C.

26. The method of claim 18 , wherein the low temperature is from approximately 110 degrees C. to approximately 225 degrees C.

27. The method of claim 18 , wherein the low temperature is from approximately 150 degrees C. to approximately 210 degrees C.

28. The method of claim 18 , wherein the low temperature is from approximately 170 degrees C. to approximately 200 degrees C.

29. The method of claim 18 , wherein the excipient further comprises glycerin.

30. The method of claim 2 , wherein the inert non-reactive compound is glycerin.

31. The method of claim 30 , wherein the glycerin is present at a concentration of at least about 1 percent of the excipient.

32. The method of claim 30 , wherein the glycerin is present at a concentration of at least about 10 percent of the excipient.

33. The method of claim 30 , wherein the glycerin is present at a concentration of at least about 30 percent of the excipient.

34. The method of claim 30 , wherein the glycerin is present at a concentration of at least about 70 percent of the excipient.

35. The method of claim 30 , wherein the glycerin is present at a concentration of at least about 85 percent of the excipient.

36. The method of claim 30 , wherein the glycerin comprises about 100 percent of the excipient.

37. The method of claim 30 , wherein the low temperature is from approximately 110 degrees C. to approximately 280 degrees C.

38. The method of claim 30 , wherein the low temperature is from approximately 150 degrees C. to approximately 280 degrees C.

39. The method of claim 30 , wherein the low temperature is from approximately 200 degrees C. to approximately 280 degrees C.

40. The method of claim 30 , wherein the low temperature is from approximately 225 degrees C. to approximately 280 degrees C.

41. The method of claim 30 , wherein the low temperature is from approximately 250 degrees C. to approximately 280 degrees C.

42. The method of claim 2 , wherein the sexual aid comprises at least approximately 0.5% of the medicant solution.

43. The method of claim 2 , wherein the sexual aid comprises approximately 0.5% to approximately 50% of the medicant solution.

44. The method of claim 2 , wherein the sexual aid comprises approximately 0.5% to approximately 20% of the medicant solution.

45. The method of claim 2 , wherein the sexual aid comprises approximately 0.5% to approximately 15% of the medicant solution.

46. The method of claim 2 , wherein the sexual aid comprises approximately 0.5% to approximately 10% of the medicant solution.

47. The method of claim 2 , wherein the sexual aid comprises approximately 5% of the medicant solution.

48. The method of claim 3 , wherein the sexual aid comprises at least approximately 0.5% of the medicant solution.

49. A method for delivering medicants through inhalation, comprising:

a. acquiring a medicant solution suitable for vaporization at a low temperature with a low temperature vaporizer having a heating element, the medicant solution, comprising:

i. an excipient comprising an inert non-reactive compound, and

ii. a sexual aid comprising icariin; and

b. vaporizing the medicant solution at the low temperature such that an effective serving of the sexual aid is provided to the user for inhalation, wherein the heating element provides the low temperature from approximately 90 degrees C. to approximately 280 degrees C.

50. The method of claim 49 , wherein the step of vaporizing the medicant solution comprises using a low temperature vaporizer.

51. The method of claim 49 , wherein the inert non-reactive compound is polysorbate.

52. The method of claim 51 , wherein the polysorbate is present at a concentration of at least about 1 percent of the excipient.

53. The method of claim 51 , wherein the polysorbate is present at a concentration of at least about 10 percent of the excipient.

54. The method of claim 51 , wherein the polysorbate is present at a concentration of at least about 30 percent of the excipient.

55. The method of claim 51 , wherein the polysorbate is present at a concentration of at least about 70 percent of the excipient.

56. The method of claim 51 , wherein the polysorbate is present at a concentration of at least about 85 percent of the excipient.

57. The method of claim 51 , wherein the polysorbate comprises about 100 percent of the excipient.

58. The method of claim 51 , wherein the low temperature is about 90 degrees C. to about 200 degrees C.

59. The method of claim 51 , wherein the low temperature is about 90 degrees C. to about 180 degrees C.

60. The method of claim 51 , wherein the low temperature is about 90 degrees C. to about 160 degrees C.

61. The method of claim 51 , wherein the low temperature is about 90 degrees C. to about 150 degrees C.

62. The method of claim 51 , wherein the low temperature is about 90 degrees C. to about 140 degrees C.

63. The method of claim 51 , wherein the low temperature is about 90 degrees C. to about 120 degrees C.

64. The method of claim 49 , wherein the excipient comprises any one or more polysorbate compound selected from the group consisting of polysorbate 20,polysorbate 40, polysorbate 60, and polysorbate 80.

65. The method of claim 49 , wherein the inert non-reactive compound is propylene glycol.

66. The method of claim 65 , wherein the propylene glycol is present at a concentration of at least about 1 percent of the excipient.

67. The method of claim 65 , wherein the propylene glycol is present at a concentration of at least about 10 percent of the excipient.

68. The method of claim 65 , wherein the propylene glycol is present at a concentration of at least about 30 percent of the excipient.

69. The method of claim 65 , wherein the propylene glycol is present at a concentration of at least about 70 percent of the excipient.

70. The method of claim 65 , wherein the propylene glycol is present at a concentration of at least about 85 percent of the excipient.

71. The method of claim 65 , wherein the propylene glycol comprises 100 percent of the excipient.

72. The method of claim 65 , wherein the low temperature is from approximately 90 degrees C. to approximately 250 degrees C.

73. The method of claim 65 , wherein the low temperature is from approximately 110 degrees C. to approximately 225 degrees C.

74. The method of claim 65 , wherein the low temperature is from approximately 150 degrees C. to approximately 210 degrees C.

75. The method of claim 65 , wherein the low temperature is from approximately 170 degrees C. to approximately 200 degrees C.

76. The method of claim 65 , wherein the excipient further comprises glycerin.

77. The method of claim 49 wherein the inert non-reactive compound is glycerin.

78. The method of claim 77 , wherein the glycerin is present at a concentration of at least about 1 percent of the excipient.

79. The method of claim 77 , wherein the glycerin is present at a concentration of at least about 10 percent of the excipient.

80. The method of claim 77 , wherein the glycerin is present at a concentration of at least about 30 percent of the excipient.

81. The method of claim 77 , wherein the glycerin is present at a concentration of at least about 70 percent of the excipient.

82. The method of claim 77 , wherein the glycerin is present at a concentration of at least about 85 percent of the excipient.

83. The method of claim 77 , wherein the glycerin comprises about 100 percent of the excipient.

84. The method of claim 77 , wherein the low temperature is from approximately 110 degrees C. to approximately 280 degrees C.

85. The method of claim 77 , wherein the low temperature is from approximately 150 degrees C. to approximately 280 degrees C.

86. The method of claim 77 , wherein the low temperature is from approximately 200 degrees C. to approximately 280 degrees C.

87. The method of claim 77 , wherein the low temperature is from approximately 225 degrees C. to approximately 280 degrees C.

88. The method of claim 77 , wherein the low temperature is from approximately 250 degrees C. to approximately 280 degrees C.

89. The method of claim 49 , wherein the sexual aid comprises approximately 0.5% to approximately 50% of the medicant solution.

90. The method of claim 49 , wherein the sexual aid comprises approximately 0.5% to approximately 20% of the medicant solution.

91. The method of claim 49 , wherein the sexual aid comprises approximately 0.5% to approximately 15% of the medicant solution.

92. The method of claim 49 , wherein the sexual aid comprises approximately 0.5% to approximately 10% of the medicant solution.

93. The method of claim 49 , wherein the sexual aid comprises approximately 5% of the medicant solution.

Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 22, 2020
From: XTEN CAPITAL GROUP, INC.
To: CQENS TECHNOLOGIES, INC.
Reel/Frame 054143/0130 →
CHANGE OF NAME Recorded Apr 23, 2020
From: CHONG CORPORATION
To: XTEN CAPITAL GROUP, INC.
Reel/Frame 052484/0850 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 27, 2016
From: CHONG, ALEXANDER CHINHAK; BARTKOWSKI, WILLIAM P.; THOMPSON, MARSHALL A.
To: CHONG CORPORATION
Reel/Frame 037600/0930 →
Continuity (9)
Continuation In Part 14937737 · Nov 10, 2015
Continuation In Part 14629279 · Feb 23, 2015
Continuation In Part 13653320 · Oct 16, 2012
Continuation In Part 12858382 · Aug 17, 2010
Continuation In Part 13846617 · Mar 18, 2013
Continuation In Part 12858373 · Aug 17, 2010
Provisional Application 61234562 · Aug 17, 2009
Provisional Application 61234560 · Aug 17, 2009
Related Publication 20160143974A1 · May 26, 2016