IP Library Granted Patent US 10,730,890
Granted Patent B2
US 10,730,890 · App. 15/008,875 · Granted Aug 4, 2020

Phthalocyanine derivative consisting of a mixture of 4 isomers

Inventors: Gabrio Roncucci (Poggibonsi, IT); Donata Dei (San Gimignano, IT); Giacomo Chiti (Prato, IT); Daniele Nistri (Prato, IT)
Assignee: MOLTENI THERAPEUTICS S.R.L.
C07F3/06A61K31/409C07D487/22
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Quick Facts
Patent No.
US 10,730,890
App. No.
15/008,875
Granted
Aug 4, 2020
Kind
B2
Abstract

There is described a phthalocyanine derivative of formula (I) consisting of 4 isomers wherein the relative isomer B content is less than or equal to 1% by weight.

Claims (6)

1. An isomeric mixture of a phthalocyanine derivative of formula (I)

wherein said isomeric mixture consists of:

wherein isomer B is present in the mixture at ≤1% by weight and non-isomeric impurities are present in the mixture at a level of <0.1% by weight.

2. The isomeric mixture of claim 1 wherein the isomer B is present in the mixture at <0.2% by weight and isomer A is present in the mixture at <12.5% by weight.

3. The isomeric mixture of claim 2 wherein the isomers A/C/D are present in the mixture in the following relative contents: 5.5-7.0% (A), 56.0-63.5% (C), and 30.0-38.0% (D).

4. A pharmaceutical composition comprising the isomeric mixture of claim 2 in combination with a pharmaceutically acceptable excipient diluent or chelating agent.

Assignments (3)
CORRECTIVE ASSIGNMENT TO CORRECT THE THE ADDRESS OF THE RECEIVING PARTY AND REMOVE PATENTS 8064404 AND 8741262 PREVIOUSLY RECORDED AT REEL: 66354 FRAME: 905. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT. Recorded Feb 7, 2024
From: MOLTENI THERAPEUTICS S.R.L.
To: L. MOLTENI & C. DEI FRATELLI ALITTI – SOCIETA’ DI ESERCIZIO - S.P.A
Reel/Frame 066538/0899 →
MERGER Recorded Jan 19, 2024
From: MOLTENI THERAPEUTICS S.R.L.
To: L. MOLTENI & C. DEI FRATELLI ALITTI - SOCIETA' DI ESERCIZIO - S.P.A.
Reel/Frame 066354/0905 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 11, 2016
From: RONCUCCI, GABRIO; DEI, DONATA; CHITI, GIACOMO; NISTRI, DANIELE
To: MOLTENI THERAPEUTICS S.R.L.
Reel/Frame 039119/0608 →
Priority Claims (1)
IT FI2009A0168 · Jul 30, 2009 · national
Continuity (2)
Division 13387407
Related Publication 20170073358A1 · Mar 16, 2017