IP Library Granted Patent US 10,195,320
Granted Patent B2
US 10,195,320 · App. 15/018,800 · Granted Feb 5, 2019

Blood filtering component, apparatus, and method

Inventors: Theresa Fisher (Lakewood, CO); Gene Parunak (Saline, MI); Rick Routson (Ypsilanti, MI); Steve Meines (Ypsilanti, MI); Gillian Henker (Baltimore, MD); Caitlin Winget (Shelburne, VT); Rajen Kumar (Troy, MI)
Assignee: Sisu Global Health, Inc.
A61M1/0281A61M1/0005A61M1/0056B01D35/30B01L2400/0638
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Quick Facts
Patent No.
US 10,195,320
App. No.
15/018,800
Granted
Feb 5, 2019
Kind
B2
Abstract

An apparatus including a hollow body, an inlet fluidly coupled to the hollow body, a piston slidably engaged within the hollow body, and a filter module arranged within the hollow body between the inlet and piston. The piston and hollow body cooperatively generate a negative pressure, relative to ambient, within the hollow body during distal piston translation from a first position to a second position, thereby drawing a fluid, such as blood, through the filter module into the hollow body. The piston and hollow body cooperatively generate a positive pressure, relative to ambient, within the hollow body during piston translation from the second position to the first position to egress the filtered fluid from the hollow body. The filter module may include a filter housing, a filter medium disposed within the housing, and a body valve configured to seal an open distal face of the filter housing.

Claims (32)

1. A removable filter module for a blood filtering apparatus, comprising:

a filter housing formed of one or more side walls, the filter housing having a partially or fully open proximal face and distal face;

a filter medium disposed within the filter housing,

wherein the filter medium is formed of a mesh comprising pleated triangle-shaped facets, and

wherein the mesh has a plurality of pores sized to prevent passage of blood clots and large biological particulates through the pores while permitting passage of blood cells through the pores;

a body valve positioned on a proximal end of the filter housing, wherein the body valve is partially attached to the filter housing via a joint, the body valve being movable between an open and a closed configuration, wherein, in the closed configuration, the body valve seals an entire surface of the proximal face of the filter housing, and wherein, in the open configuration, the body valve bends at the joint such that one or more unattached portions of the body valve move outward away from the filter housing;

an inlet positioned on a distal end of the body valve and configured to receive blood; and

a hollow body positioned at a proximal end of the body valve and configured to store filtered blood,

wherein the hollow body comprises an outlet on a sidewall of the hollow body, the outlet configured to egress filtered blood.

2. The removable filter module of claim 1 , wherein the filter module is sized and configured to fit securely within a blood filtering apparatus and to form a liquid-tight seal with an inner wall of the blood filtering apparatus.

3. The removable filter module of claim 2 , further comprising a sealing surface protruding from the one or more side walls of the filter housing, wherein the sealing surface is configured to compress against the inner wall of the blood filtering apparatus.

4. The removable filter module of claim 3 , wherein the filter housing and the sealing surface are monolithic.

5. The removable filter module of claim 3 , wherein the filter housing, the sealing surface, and the body valve are monolithic.

6. The removable filter module of claim 2 , wherein the body valve opens when a negative pressure is created within the blood filtering apparatus.

7. The removable filter module of claim 1 , wherein the filter housing is cylindrical.

8. The removable filter module of claim 1 , wherein the filter housing is transparent.

9. The filter removable filter module of claim 1 , wherein the filter medium comprises a biocompatible material.

10. The removable filter module of claim 9 , wherein the biocompatible material includes nylon or polyester.

11. A filter module, comprising:

a filter medium formed of a mesh, wherein the mesh has a plurality of pores sized to prevent passage of blood clots and large biological particulates through the pores while permitting passage of blood cells through the pores;

an elastomeric housing disposed at least partially around the filter medium,

wherein the elastomeric housing comprises an inner column configured to create a hollow inner surface between a sidewall of the elastomeric housing and the inner column,

wherein the elastomeric housing further comprises a sealing surface configured to create a seal between the filter module and a fluid uptake device configured to receive the filter module, and

wherein the filter medium is positioned in a circle around the inner column; and

a mechanical body valve configured to mechanically seal the filter module, wherein the elastomeric housing, the sealing surface, the mechanical body valve, and the inner column are monolithic.

12. The filter module of claim 11 , wherein the mechanical body valve opens to allow fluid to flow through the filter medium when subjected to a negative pressure and closes with ambient or positive pressure.

13. The filter module of claim 11 , wherein the mechanical body valve closes when external pressure is applied on the filter module and opens when pressure within the filter module is increased.

14. The filter module of claim 13 , wherein the mechanical body valve comprises a flap, wherein the flap is partially attached to the elastomeric housing via a joint, wherein the flap is configured to bend along the joint such that an unattached portion of the flap moves outward away from the elastomeric housing.

15. A blood filtering apparatus, comprising:

a fluid uptake device comprising a fluid passageway; and

the filter module of claim 11 disposed within the passageway of the fluid uptake device.

16. The filter module of claim 11 , wherein the filter medium is cylindrical.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 25, 2018
From: FISHER, THERESA; PARUNAK, GENE; ROUTSON, RICK; MEINES, STEVE; HENKER, GILLIAN; WINGET, CAITLIN; KUMAR, RAJEN
To: SISU GLOBAL HEALTH, INC.
Reel/Frame 046195/0020 →
Continuity (3)
Continuation In Part 13445837 · Apr 12, 2012
Provisional Application 62276817 · Jan 8, 2016
Related Publication 20160151550A1 · Jun 2, 2016
Cited By (13)
US 12,239,333 US 12,251,120 US 12,263,100 US 12,274,459 US 12,310,608 US 12,343,028 US 12,364,496 US 12,465,382 US 12,496,081 US 12,558,112 US 12,558,486 US 12,685,549 US 12,702,538