IP Library Granted Patent US 11,083,387
Granted Patent B2
US 11,083,387 · App. 15/034,798 · Granted Aug 10, 2021

Systems and methods for detecting nerve function

Inventors: Cameron Mahon (Hunt Valley, MD); Curt H. Labelle (Hunt Valley, MD)
Assignee: SafeOp Surgical, Inc.
A61B5/04001A61B5/0004A61B5/0478A61B5/0484A61B5/4047A61B5/7225A61N1/0456A61N1/0492A61N1/36014A61B2505/05
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Quick Facts
Patent No.
US 11,083,387
App. No.
15/034,798
Granted
Aug 10, 2021
Kind
B2
Abstract

The present technology relates generally to the field of electrophysiology and specifically to automated devices, components, systems, and related methods for monitoring potential injury to the nervous system using evoked potentials during intraoperative neurophysiologic monitoring.

Claims (11)

1. A method for intraoperative determination and monitoring of a plurality of resultant electrical waveforms of a patient, the method comprising:

stimulating, via a stimulating electrode positioned on skin of the patient, the stimulating comprising transmitting a plurality of time-locked electrical stimuli, the stimulating electrode in communication with an evoked potential detection device configured to monitor one or more peripheral nerves of the patient;

recording, via a recording electrode positioned on the skin of the patient, the plurality of resultant electrical waveforms received by the evoked potential detection device, the resultant electrical waveforms generated by the body's nervous system in response to the time-locked electrical stimuli;

developing, by the evoked potential detection device, an initial baseline waveform from an average of the plurality of resultant electrical waveforms;

stimulating, via the stimulating electrode by the evoked potential detection device, an additional electrical stimulus;

recording, via the recording electrode by the evoked potential detection device, an additional resultant electrical waveform;

determining, by the evoked potential detection device, if the additional resultant electrical waveform should be indicated as a good response by:

comparing, by the evoked potential detection device, the additional resultant electrical waveform to the initial baseline waveform;

if the additional resultant electrical waveform should be indicated as a good response, developing, by the evoked potential detection device, an updated baseline waveform, wherein the updated baseline waveform is a weighted average of the initial baseline waveform and the additional resultant electrical waveform; and

if the additional resultant electrical waveform should not be indicated as a good response, setting the updated baseline waveform to the initial baseline waveform.

2. The method of claim 1 , further comprising sending, by the evoked potential detection device, a data output to a user interface, the data output comprising an indication of whether the additional resultant electrical waveform is acceptable.

Assignments (9)
CONFIRMATORY GRANT OF SECURITY INTEREST IN UNITED STATES PATENTS Recorded May 12, 2026
From: ALPHATEC SPINE, INC.; SAFEOP SURGICAL, INC.
To: JPMORGAN CHASE BANK, N.A.
Reel/Frame 075560/0884 →
RELEASE OF PATENT SECURITY INTEREST AT REEL/FRAME NO. 62681/0020 Recorded May 1, 2026
From: WILMINGTON TRUST, NATIONAL ASSOCIATION, AS AGENT
To: ALPHATEC SPINE, INC.; SAFEOP SURGICAL, INC.
Reel/Frame 075385/0575 →
RELEASE OF SECURITY INTEREST IN PATENT COLLATERAL AT REEL/FRAME NO. 62310/0001 Recorded May 1, 2026
From: MIDCAP FUNDING IV TRUST, AS AGENT
To: ALPHATEC SPINE, INC.; SAFEOP SURGICAL, INC.
Reel/Frame 075316/0001 →
SECURITY INTEREST Recorded Feb 7, 2023
From: ALPHATEC SPINE, INC.; SAFEOP SURGICAL, INC.
To: WILMINGTON TRUST, NATIONAL ASSOCIATION
Reel/Frame 062681/0020 →
SECURITY INTEREST Recorded Jan 6, 2023
From: ALPHATEC SPINE, INC.; SAFEOP SURGICAL, INC.
To: MIDCAP FUNDING IV TRUST
Reel/Frame 062310/0001 →
RELEASE OF SECURITY INTEREST IN PATENT COLLATERAL AT REEL/FRAME NO. 48101/0635 Recorded Aug 11, 2021
From: SQUADRON MEDICAL FINANCE SOLUTIONS LLC
To: SAFEOP SURGICAL, INC.
Reel/Frame 057177/0718 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 5, 2020
From: MAHON, CAMERON
To: SAFEOP SURGICAL, INC.
Reel/Frame 052578/0233 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 5, 2020
From: LABELLE, CURT
To: SAFEOP SURGICAL, INC.
Reel/Frame 052578/0241 →
SECURITY INTEREST Recorded Nov 9, 2018
From: SAFEOP SURGICAL, INC.
To: SQUADRON MEDICAL FINANCE SOLUTIONS LLC
Reel/Frame 048101/0635 →