IP Library › Granted Patent US 11,066,398
Granted Patent B2
US 11,066,398 · App. 15/035,842 · Granted Jul 20, 2021

Small molecule c-Myc inhibitors

Inventors: Peter K. Vogt (La Jolla, CA); Francis X. Tavares (Durham, NC); Kim D. Janda (La Jolla, CA)
Assignees: The Scripps Research Institute; Sorrento Therapeutics, Inc.
C07D413/14A61K31/44A61K31/4418A61P35/00C07D213/56C07D213/74C07D401/04C07D405/04C07D405/14C07D413/04
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Quick Facts
Patent No.
US 11,066,398
App. No.
15/035,842
Granted
Jul 20, 2021
Kind
B2
Abstract

This invention provides small molecule Myc-inhibitors. Also provided in the invention are therapeutic applications of these compounds for treating Myc-driven cancer and other related methods.

Claims (1)

1. A method of treating c-Myc driven cancer, comprising administering an effective amount of 4-(2-(furan-2-yl)-6-(4-nitrophenyl)pyridin-4-yl)benzamide (CG-RS-44).

Assignments (11)
TERMINATION AND RELEASE OF SECURITY INTEREST IN INTELLECTUAL PROPERTY Recorded Sep 21, 2023
From: SCILEX HOLDING COMPANY
To: SORRENTO THERAPEUTICS, INC.; SCINTILLA PHARMACEUTICALS, INC.
Reel/Frame 065017/0844 →
RELEASE OF SECURITY INTEREST Recorded Aug 11, 2023
From: JMB CAPITAL PARTNERS LENDING, LLC
To: SORRENTO THERAPEUTICS, INC.; SCINTILLA PHARMACEUTICALS, INC.
Reel/Frame 064571/0848 →
SECURITY INTEREST Recorded Jul 31, 2023
From: SORRENTO THERAPEUTICS, INC.; SCINTILLA PHARMACEUTICALS, INC.
To: SCILEX HOLDING COMPANY
Reel/Frame 064441/0575 →
SECURITY INTEREST Recorded Apr 6, 2023
From: SORRENTO THERAPEUTICS, INC.; SCINTILLA PHARMACEUTICALS, INC.
To: JMB CAPITAL PARTNERS LENDING, LLC
Reel/Frame 063283/0063 →
RELEASE OF SECURITY INTEREST Recorded Jul 31, 2020
From: OAKTREE FUND ADMINISTRATION, LLC
To: SORRENTO THERAPEUTICS, INC.; TNK THERAPEUTICS, INC.; CONCORTIS BIOSYSTEMS, CORP.; ARK ANIMAL HEALTH, INC.; SCINTILLA PHARMACEUTICALS, INC.
Reel/Frame 053368/0577 →
CONFIRMATORY LICENSE Recorded Jun 20, 2019
From: THE SCRIPPS RESEARCH INSTITUTE
To: NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR
Reel/Frame 049537/0512 →
CONFIRMATORY LICENSE Recorded Jun 20, 2019
From: THE SCRIPPS RESEARCH INSTITUTE
To: NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR
Reel/Frame 049537/0959 →
SECURITY INTEREST Recorded Nov 7, 2018
From: SORRENTO THERAPEUTICS, INC.; TNK THERAPEUTICS, INC.; CONCORTIS BIOSYSTEMS, CORP.; ARK ANIMAL HEALTH, INC.; SCINTILLA PHARMACEUTICALS, INC.
To: OAKTREE FUND ADMINISTRATION, LLC
Reel/Frame 047446/0335 →
CONFIRMATORY LICENSE Recorded Dec 27, 2017
From: SCRIPPS RESEARCH INSTITUTE
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 044963/0674 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 31, 2017
From: TAVARES, FRANCIS X.
To: SORRENTO THERAPEUTICS, INC.
Reel/Frame 041812/0102 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 31, 2017
From: JANDA, KIM D.; VOGT, PETER K.
To: THE SCRIPPS RESEARCH INSTITUTE
Reel/Frame 041812/0207 →