Disposable thermal in-vitro diagnostic apparatus
A portable, disposable in-vitro diagnostic apparatus is provided. The apparatus includes a body configured to be hand held. The body has a reaction medium supply chamber configured in selective fluid communication with a reaction chamber via a fluid conveying channel. The reaction chamber is located beneath a sample reaction chamber. The reaction medium supply chamber contains a reaction fluid therein and the reaction chamber contains a thermal reaction medium therein. The reaction fluid is selectively reactive with the thermal reaction medium to produce one of an endothermic or exothermic reaction beneath the sample reaction chamber.
1. A portable, disposable in-vitro diagnostic apparatus, comprising:
a body configured to be hand held, said body having a reaction medium supply chamber configured in selective fluid communication with a reaction chamber via a fluid conveying channel, said reaction chamber being beneath a sample reaction chamber, said reaction medium supply chamber containing a reaction fluid therein and said reaction chamber containing a thermal reaction medium therein, said reaction fluid being reactive with said thermal reaction medium to produce one of an endothermic or exothermic reaction beneath said sample reaction chamber.
2. The portable, disposable in-vitro diagnostic apparatus of claim 1 further comprising a conductive barrier separating said sample reaction chamber from said reaction chamber.
3. The portable, disposable in-vitro diagnostic apparatus of claim 2 further comprising an overflow chamber downstream from said reaction chamber.
4. The portable, disposable in-vitro diagnostic apparatus of claim 3 wherein said overflow chamber includes a hydrophobic membrane.
5. The portable, disposable in-vitro diagnostic apparatus of claim 1 further comprising a rupturable membrane selectively closing off said fluid conveying channel from said reaction medium supply chamber.
6. The portable, disposable in-vitro diagnostic apparatus of claim 5 wherein said fluid conveying channel includes a fluid wicking material contained therein.
7. The portable, disposable in-vitro diagnostic apparatus of claim 1 further including a self-actuatable valve disposed between said fluid conveying channel and said reaction chamber, said self-actuatable valve being movable between a closed position to close off said fluid conveying channel from said reaction chamber and an open position to allow fluid to flow from said fluid conveying channel into said reaction chamber.
8. The portable, disposable in-vitro diagnostic apparatus of claim 7 wherein said self-actuable valve moves between said open position and closed position in response to the endothermic or exothermic reaction.
9. The portable, disposable in-vitro diagnostic apparatus of claim 8 wherein said self-actuatable valve is a bimetallic material.
10. The portable, disposable in-vitro diagnostic apparatus of claim 8 wherein said self-actuatable valve is a heat memory alloy.
11. The portable, disposable in-vitro diagnostic apparatus of claim 1 wherein at least a portion of said thermal reaction medium is buffered.
12. The portable, disposable in-vitro diagnostic apparatus of claim 1 wherein said body is configured for electrical communication with an external power source.