Tissue processing device and associated systems and methods
View Patent ↗Tissue processing devices are provided. The tissue processing devices can be used to process and transport tissue in a closed and continuous environment. The devices can be used for adipose tissue transfer, including autologous fat grafting.
1. A tissue processing device, comprising:
a body including a cavity formed therein, the cavity comprising a first cylindrical compartment and a second compartment, and the body defining a proximal end and a distal end;
a tissue collection port formed in a wall of the body adapted to receive tissue therethrough and in fluid communication with the cavity;
a rotary transfer device including a helical blade within the first cylindrical compartment for transferring the tissue from the proximal end to the distal end of the body;
a filter separating the first cylindrical compartment from the second compartment, wherein the filter defines at least a portion of a wall surrounding the rotary transfer device; and
a port formed in the body adapted for removal therethrough of the tissue from the cavity.
2. The tissue processing device of claim 1 , wherein the tissue collection port and the port formed in the body are in fluid communication with the first cylindrical compartment.
3. The tissue processing device of claim 1 , comprising at least one injection port formed in fluid communication with the cavity and adapted for injection of a wash solution therethrough.
4. The tissue processing device of claim 1 , comprising a vacuum port in fluid communication with the second compartment.
5. The tissue processing device of claim 1 , wherein the filter is a mesh filter.
6. The tissue processing device of claim 1 , wherein during transfer of the tissue from the proximal end to the distal end of the body, undesired components are filtered through the filter and transferred from the first cylindrical compartment to the second compartment.
7. The tissue processing device of claim 1 , wherein during transfer of the tissue from the proximal end to the distal end of the body, the tissue is processed and cleaned for transplantation.
8. The tissue processing device of claim 1 , comprising a crank for rotatably driving the rotary transfer device.
9. The tissue processing device of claim 1 , comprising an automated actuation means for rotatably driving the rotary transfer device.
10. The tissue processing device of claim 1 , wherein the rotary transfer device comprises at least one catcher extending from a rotatable shaft.
11. The tissue processing device of claim 1 , wherein the body and the rotary transfer device define a low-shear environment.
12. The tissue processing device of claim 11 , wherein the adipose tissue is human adipose tissue.
13. The tissue processing device of claim 1 , wherein the helical blade is substantially aligned with a longitudinal axis of the first cylindrical compartment.
14. The tissue processing device of claim 1 , wherein the helical blade rotates such that a peripheral edge of the helical blade moves proximate an inner wall of the first cylindrical compartment.
15. A method of processing tissue, comprising:
providing a tissue processing device, the tissue processing device including:
a body including a cavity formed therein, the cavity comprising a first cylindrical compartment and a second compartment, and the body defining a proximal end and a distal end;
a tissue collection port in fluid communication with the cavity,
a rotary transfer device including a helical blade within the first cylindrical compartment;
a filter separating the first cylindrical compartment from the second compartment, wherein the filter defines at least a portion of a wall surrounding the rotary transfer device; and
a port formed in the body;
introducing tissue for processing through the tissue collection port and into the cavity;
transferring the tissue from the proximal end to the distal end of the body with the rotary transfer device; and
removing the tissue from the cavity through the port after the tissue has been processed.
16. The method of claim 15 , comprising injecting a wash solution into the cavity through at least one injection port formed in the body to clean and process the tissue.
17. The method of claim 15 , wherein the filter is a mesh filter.
18. The method of claim 15 , further comprising filtering the tissue of undesired components through the filter during transfer of the tissue from the proximal end to the distal end of the body.
19. The method of claim 15 , wherein the helical blade is substantially aligned with a longitudinal axis of the first cylindrical compartment.
20. The method of claim 15 , wherein the helical blade rotates such that a peripheral edge of the helical blade moves proximate an inner wall of the first cylindrical compartment.
21. A system of tissue processing, comprising:
a tissue processing device, the tissue processing device including:
a body including a cavity formed therein, the cavity comprising a first cylindrical compartment and a second compartment, and the body defining a proximal end and a distal end;
a tissue collection port formed in the body adapted to receive tissue for processing therethrough and in fluid communication with the cavity;
a rotary transfer device including a helical blade within the first cylindrical compartment for transferring the tissue from the proximal end to the distal end of the body;
a filter separating the first cylindrical compartment from the second compartment, wherein the filter defines at least a portion of a wall surrounding the rotary transfer device; and
a port formed in the body adapted for removal therethrough of the tissue from the cavity;
a source of the tissue for introduction of the tissue into the tissue collection port; and
an injection device for removal of the tissue from the port.
22. The system of claim 21 , comprising a source of wash solution for introduction into the cavity through an injection port formed in the body.
23. The system of claim 21 , comprising a vacuum source for extruding undesired components from the second compartment through a vacuum port.
24. The system of claim 21 , wherein the helical blade is substantially aligned with a longitudinal axis of the first cylindrical compartment.
25. The system of claim 21 , wherein the helical blade rotates such that a peripheral edge of the helical blade moves proximate an inner wall of the first cylindrical compartment.