IP Library Patent Application 15055499
Patent Application
App. No. 15/055,499

COMPOSITIONS COMPRISING COMBINATIONS OF PURIFIED CANNABINOIDS, WITH AT LEAST ONE FLAVONOID, TERPENE, OR MINERAL

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Patent No.
US None
App. No.
15/055,499
Abstract

Disclosed herein are new compositions having combinations of purified cannabinoids. One embodiment of this disclosure provides compositions having one or more purified cannabinoids in combination with a purified terpene. One embodiment of this disclosure provides compositions having one or more purified cannabinoids in combination with a purified flavonoid. One embodiment of this disclosure provides compositions having one or more purified cannabinoids in combination with a purified mineral.

Claims (34)

1 . A composition comprising:

a first purified cannabinoid; and

a compound chosen from a second purified cannabinoid, a purified terpene, a purified flavonoid, and a purified mineral,

wherein the said composition is substantially free from cellulose.

2 . The composition of claim 1 , comprising a purified mineral.

3 . The composition of claim 2 , wherein the purified mineral is lithium.

4 . The composition of claim 2 , consisting essentially of a first purified cannabinoid and a purified mineral.

5 . The composition of claim 1 , comprising a purified terpene.

6 . The composition of claim 5 , wherein the terpene is chosen from 7,8-dihydroionone, Acetanisole, Acetic Acid, Acetyl Cedrene, Anethole, Anisole, Benzaldehyde, Bergamotene (α-cis-Bergamotene) (α-trans-Bergamotene), Bisabolol (β-Bisabolol), Borneol, Butanoic/Butyric Acid, Cadinene (α-Cadinene) (γ-Cadinene), Cafestol, Caffeic acid, Camphene, Camphor, Capsaicin, Carene (Δ-3-Carene), Carotene, Carvacrol, Carvone, Dextro-Carvone, Laevo-Carvone, Caryophyllene (β-Caryophyllene), Caryophyllene oxide, Castoreum Absolute, Cedrene (α-Cedrene) (β-Cedrene), Cedrene Epoxide (α-Cedrene Epoxide), Cedrol, Cembrene, Chlorogenic Acid, Cinnamaldehyde (α-amyl-Cinnamaldehyde) (α-hexyl-Cinnamaldehyde), Cinnamic Acid, Cinnamyl Alcohol, Citronellal, Citronellol, Cryptone, Curcumene (α-Curcumene) (γ-Curcumene), Decanal, Dehydrovomifoliol, Diallyl Disulfide, Dihydroactinidiolide, Dimethyl Disulfide, Eicosane/Icosane, Elemene (β-Elemene), Estragole, Ethyl acetate, Ethyl Cinnamate, Ethyl maltol, Eucalyptol/1,8-Cineole, Eudesmol (α-Eudesmol) (μ-Eudesmol) (γ-Eudesmol), Eugenol, Euphol, Farnesene, Farnesol, Fenchol (β-Fenchol), Fenchone, Geraniol, Geranyl acetate, Germacrenes, Germacrene B, Guaia-1(10), 11-diene, Guaiacol, Guaiene (α-Guaiene), Gurjunene (α-Gurjunene), Herniarin, Hexanaldehyde, Hexanoic Acid, Humulene (α-Humulene) (β-Humulene), Ionol (3-oxo-α-ionol) (β-Ionol), Ionone (α-Ionone) (β-Ionone), Ipsdienol, Isoamyl acetate, Isoamyl Alcohol, Isoamyl Formate, Isoborneol, Isomyrcenol, Isopulegol, Isovaleric Acid, Isoprene, Kahweol, Lavandulol, Limonene, γ-Linolenic Acid, Linalool, Longifolene, α-Longipinene, Lycopene, Menthol, Methyl butyrate, 3-Mercapto-2-Methylpentanal, Mercaptan/Thiols, β-Mercaptoethanol, Mercaptoacetic Acid, Allyl Mercaptan, Benzyl Mercaptan, Butyl Mercaptan, Ethyl Mercaptan, Methyl Mercaptan, Furfuryl Mercaptan, Ethylene Mercaptan, Propyl Mercaptan, Thenyl Mercaptan, Methyl Salicylate, Methylbutenol, Methyl-2-Methylvalerate, Methyl Thiobutyrate, Myrcene (β-Myrcene), γ-Muurolene, Nepetalactone, Nerol, Nerolidol, Neryl acetate, Nonanaldehyde, Nonanoic Acid, Ocimene, Octanal, Octanoic Acid, P-cymene, Pentyl butyrate, Phellandrene, Phenylacetaldehyde, Phenylethanethiol, Phenylacetic Acid, Phytol, Pinene, β-Pinene, Propanethiol, Pristimerin, Pulegone, Retinol, Rutin, Sabinene, Sabinene Hydrate, cis-Sabinene Hydrate, trans-Sabinene Hydrate, Safranal, α-Selinene, α-Sinensal, β-Sinensal, β-Sitosterol, Squalene, Taxadiene, Terpin hydrate, Terpineol, Terpine-4-ol, α-Terpinene, γ-Terpinene, Terpinolene, Thiophenol, Thujone, Thymol, α-Tocopherol, Tonka Undecanone, Undecanal, Valeraldehyde/Pentanal, Verdoxan, α-Ylangene, Umbelliferone, or Vanillin.

7 . The composition of claim 5 , wherein the terpene is chosen from Alpha-terpineol, Bergamotene (α-cis-Bergamotene) (α-trans-Bergamotene), Bisabolol (β-Bisabolol), Borneol, Camphor, Capsaicin, Carvacrol, Caryophyllene (β-Caryophyllene), Caryophyllene oxide, Cineole, Cinnamaldehyde (α-amyl-Cinnamaldehyde) (α-hexyl-Cinnamaldehyde), Cinnamyl Alcohol, Citronellal, Citronellol, Ethyl, Cinnamate, Eucalyptol/1,8-Cineole, Farnesol, Fenchol (β-Fenchol), Geranyl acetate, Germacrene B, Guaiene (α-Guaiene), Humulene (α-Humulene) (β-Humulene), Ionol (3-oxo-α-ionol) (β-Ionol), Ionone (α-Ionone) (β-Ionone), Isoamyl acetate, Isoprene, Kahweol, Laevo-Carvone, Lavandulol, Limonene, Linalool, Linalyl acetate, Luteolin, Lycopene, Menthol, Myrcene (β-Myrcene), Nerol, Nerolidol, Neryl acetate, P-cymene, Phytol, Pinene, Pristimerin, Retinol, Terpin hydrate, Terpineol, Terpinol-4-ol, Terpinolene, Thujone, Thymol, or Vanillin.

8 . The composition of claim 5 , comprising of Cannabigerolic Acid (CBGA), Cannabigerolic Acid monomethylether (CBGAM), Cannabigerol (CBG), Cannabigerol monomethylether (CBGM), Cannabigerovarinic Acid (CBGVA), Cannabigerovarin (CBGV), Cannabichromenic Acid (CBCA), Cannabichromene (CBC), Cannabichromevarinic Acid (CBCVA), Cannabichromevarin (CBCV), Cannabidiolic Acid (CBDA), Cannabidiol (CBD), Cannabidiol monomethylether (CBDM), Cannabidiol-C 4 (CBD-C 4 ), Cannabidivarinic Acid (CBDVA), Cannabidivarin (CBDV), Cannabidiorcol (CBD-C 1 ), Tetrahydrocannabinolic acid A (THCA-A), Tetrahydrocannabinolic acid B (THCA-B), Tetrahydrocannabinol (THC), Tetrahydrocannabinolic acid C 4 (THCA-C 4 ), Tetrahydrocannbinol C 4 (THC-C 4 ), Tetrahydrocannabivarinic acid (THCVA), Tetrahydrocannabivarin (THCV), Tetrahydrocannabiorcolic acid (THCA-C 1 ), Tetrahydrocannabiorcol (THC-C 1 ), Delta-7-cis-iso-tetrahydrocannabivarin, Δ 8 -tetrahydrocannabinolic acid (Δ8-THCA), Δ 8 -tetrahydrocannabinol (Δ 8 -THC), Cannabicyclolic acid (CBLA), Cannabicyclol (CBL), Cannabicyclovarin (CBLV), Cannabielsoic acid A (CBEA-A), Cannabielsoic acid B (CBEA-B), Cannabielsoin (CBE), Cannabinolic acid (CBNA), Cannabinol (CBN), Cannabinol methylether (CBNM), Cannabinol-C 4 (CBN-C 4 ), Cannabivarin (CBV), Cannabino-C 2 (CBN-C 2 ), Cannabiorcol (CBN-C 1 ), Cannabinodiol (CBND), Cannabinodivarin (CBDV), Cannabitriol (CBT), 10-Ethoxy-9-hydroxy-Δ 6a -tetrahydrocannabinol, 8,9-Dihydroxy-Δ 6a(10a) -tetrahydrocannabinol (8,9-Di-OH-CBT-C 5 ), Cannabitriolvarin (CBTV), Ethoxy-cannabitriolvarin (CBTVE), Dehydrocannabifuran (DCBF), Cannbifuran (CBF), Cannabichromanon (CBCN), Cannabicitran (CBT), 10-Oxo-Δ 6a(10a) -tetrahydrocannabinol (OTHC), Δ 9 -cis-tetrahydrocannabinol (cis-THC), Cannabiripsol (CBR), 3,4,5,6-tetrahydro-7-hydroxy-alpha-alpha-2-trimethyl-9-n-propyl-2,6-methano-2H-1-benzoxocin-5-methanol (OH-iso-HHCV), Trihydroxy-delta-9-tetrahydrocannabinol (triOH-THC), Isocanabinoids, and Epigallocatechin gallate.

9 . The composition of claim 8 , wherein the first purified cannabinoid is chosen from Tetrahydrocannabinol (THC), Tetrahydrocannabivarin (THCV), Cannabichromene (CBC), Cannabichromanon (CBCN), Cannabidiol (CBD), Cannabielsoin (CBE), Cannabidivarin (CBDV), Cannbifuran (CBF), Cannabicyclol (CBL), Cannabinol (CBN), Cannabinodiol (CBND), Cannabitriol (CBT), Cannabivarin (CBV), and Isocanabinoids.

10 . The composition of claim 9 , comprising a first purified cannabinoid chosen from Cannabigerolic Acid (CBGA), Cannabigerolic Acid monomethylether (CBGAM), Cannabigerol (CBG), Cannabigerol monomethylether (CBGM), Cannabigerovarinic Acid (CBGVA), Cannabigerovarin (CBGV), Cannabichromenic Acid (CBCA), Cannabichromene (CBC), Cannabichromevarinic Acid (CBCVA), Cannabichromevarin (CBCV), Cannabidiolic Acid (CBDA), Cannabidiol (CBD), Cannabidiol monomethylether (CBDM), Cannabidiol-C 4 (CBD-C 4 ), Cannabidivarinic Acid (CBDVA), Cannabidivarin (CBDV), Cannabidiorcol (CBD-C 1 ), Tetrahydrocannabinolic acid A (THCA-A), Tetrahydrocannabinolic acid B (THCA-B), Tetrahydrocannabinol (THC), Tetrahydrocannabinolic acid C 4 (THCA-C 4 ), Tetrahydrocannbinol C 4 (THC-C 4 ), Tetrahydrocannabivarinic acid (THCVA), Tetrahydrocannabivarin (THCV), Tetrahydrocannabiorcolic acid (THCA-C 1 ), Tetrahydrocannabiorcol (THC-C 1 ), Delta-7-cis-iso-tetrahydrocannabivarin, Δ 8 -tetrahydrocannabinolic acid (Δ8-THCA), Δ 8 -tetrahydrocannabinol (Δ 8 -THC), Cannabicyclolic acid (CBLA), Cannabicyclol (CBL), Cannabicyclovarin (CBLV), Cannabielsoic acid A (CBEA-A), Cannabielsoic acid B (CBEA-B), Cannabielsoin (CBE), Cannabinolic acid (CBNA), Cannabinol (CBN), Cannabinol methylether (CBNM), Cannabinol-C 4 (CBN-C 4 ), Cannabivarin (CBV), Cannabino-C 2 (CBN-C 2 ), Cannabiorcol (CBN-C 1 ), Cannabinodiol (CBND), Cannabinodivarin (CBDV), Cannabitriol (CBT), 10-Ethoxy-9-hydroxy-Δ 6a -tetrahydrocannabinol, 8,9-Dihydroxy-Δ 6a(10a) -tetrahydrocannabinol (8,9-Di-OH-CBT-C 5 ), Cannabitriolvarin (CBTV), Ethoxy-cannabitriolvarin (CBTVE), Dehydrocannabifuran (DCBF), Cannbifuran (CBF), Cannabichromanon (CBCN), Cannabicitran (CBT), 10-Oxo-Δ 6a(10a) -tetrahydrocannabinol (OTHC), Δ 9 -cis-tetrahydrocannabinol (cis-THC), Cannabiripsol (CBR), 3,4,5,6-tetrahydro-7-hydroxy-alpha-alpha-2-trimethyl-9-n-propyl-2,6-methano-2H-1-benzoxocin-5-methanol (OH-iso-HHCV), Trihydroxy-delta-9-tetrahydrocannabinol (triOH-THC), Yangonin, Isocanabinoids, Epigallocatechin gallate, Dodeca-2E,4E,8Z,10Z-tetraenoic acid isobutylamide, or Dodeca-2E,4E-dienoic acid isobutylamide; and

a second purified cannabinoid chosen from Cannabigerolic Acid (CBGA), Cannabigerolic Acid monomethylether (CBGAM), Cannabigerol (CBG), Cannabigerol monomethylether (CBGM), Cannabigerovarinic Acid (CBGVA), Cannabigerovarin (CBGV), Cannabichromenic Acid (CBCA), Cannabichromene (CBC), Cannabichromevarinic Acid (CBCVA), Cannabichromevarin (CBCV), Cannabidiolic Acid (CBDA), Cannabidiol (CBD), Cannabidiol monomethylether (CBDM), Cannabidiol-C 4 (CBD-C 4 ), Cannabidivarinic Acid (CBDVA), Cannabidivarin (CBDV), Cannabidiorcol (CBD-C 1 ), Tetrahydrocannabinolic acid A (THCA-A), Tetrahydrocannabinolic acid B (THCA-B), Tetrahydrocannabinol (THC), Tetrahydrocannabinolic acid C 4 (THCA-C 4 ), Tetrahydrocannbinol C 4 (THC-C 4 ), Tetrahydrocannabivarinic acid (THCVA), Tetrahydrocannabivarin (THCV), Tetrahydrocannabiorcolic acid (THCA-C 1 ), Tetrahydrocannabiorcol (THC-C 1 ), Delta-7-cis-iso-tetrahydrocannabivarin, Δ 8 -tetrahydrocannabinolic acid (Δ8-THCA), Δ 8 -tetrahydrocannabinol (Δ 8 -THC), Cannabicyclolic acid (CBLA), Cannabicyclol (CBL), Cannabicyclovarin (CBLV), Cannabielsoic acid A (CBEA-A), Cannabielsoic acid B (CBEA-B), Cannabielsoin (CBE), Cannabinolic acid (CBNA), Cannabinol (CBN), Cannabinol methylether (CBNM), Cannabinol-C 4 (CBN-C 4 ), Cannabivarin (CBV), Cannabino-C 2 (CBN-C 2 ), Cannabiorcol (CBN-C 1 ), Cannabinodiol (CBND), Cannabinodivarin (CBDV), Cannabitriol (CBT), 10-Ethoxy-9-hydroxy-Δ 6a -tetrahydrocannabinol, 8,9-Dihydroxy-Δ 6a(10a) -tetrahydrocannabinol (8,9-Di-OH-CBT-C 5 ), Cannabitriolvarin (CBTV), Ethoxy-cannabitriolvarin (CBTVE), Dehydrocannabifuran (DCBF), Cannbifuran (CBF), Cannabichromanon (CBCN), Cannabicitran (CBT), 10-Oxo-Δ 6a(10a) -tetrahydrocannabinol (OTHC), Δ 9 -cis-tetrahydrocannabinol (cis-THC), Cannabiripsol (CBR), 3,4,5,6-tetrahydro-7-hydroxy-alpha-alpha-2-trimethyl-9-n-propyl-2,6-methano-2H-1-benzoxocin-5-methanol (OH-iso-HHCV), Trihydroxy-delta-9-tetrahydrocannabinol (triOH-THC), Yangonin, Isocanabinoids, Epigallocatechin gallate, Dodeca-2E,4E,8Z,10Z-tetraenoic acid isobutylamide, or Dodeca-2E,4E-dienoic acid isobutylamide.

11 . The composition of claim 1 , comprising a purified flavonoid.

12 . The composition of claim 11 , wherein the flavonoid is chosen from phenolic acids, stilbenoids, dihydroflavonols, anthocyanins, anthocyanidins, polyphenols, tannins, flavones, flavan-3-ols, Flavan-4-ol, Flavan-3,4-diol flavonols, stilbenoids, phytochemicals, antioxidants, homoisoflavonoids, phenylpropanoids, Phloroglucinols coumarins, Phenolic acids, Naphthodianthrones, Steroid glycosides, bioflavonoids, isoflavonoids, and neoflavonoids.

13 . The composition of claim 11 , wherein the flavonoid is chosen from Adenosine, Adhyperforin, amentoflavone, Anandamide, Apigenin, Cannaflavin B, Catechin (C), Catechin 3-gallate (Cg), Chlorogenic acid, cichoric acid, caftaric acid, Daidzein, Delphinidin, Eleutherosides, Epicatechin 3-gallate (ECg), Epicatechins, Epicatechin, epigallocatechin, myricetin, Oxalic acid, Pelargonidin, Tannin, Theaflavin-3-gallate, Theanine, Theobromine, Theophylline, Tryptophan, Tyramine, Xanthine, Caffeine, Cannaflavin A, Cannaflavin B, Catechin (C), Catechin 3-gallate (Cg), Epicatechin 3-gallate (ECg), Epicatechins (Epicatechin (EC)), epigallocatechin, Epigallocatechin (EGC), Epigallocatechin 3-gallate (EGCg), Gallocatechin (GC), Gallocatechin 3-gallate (GCg)), Gamma amino butyric acid, Genistein, Ginkgo biloba , Ginsenosides, Quercetin, Quercitrin, or Rutin.

14 . The composition of claim 11 , wherein the purified flavonoid is chosen from Caffeine, Cannaflavin A, Cannaflavin B, Catechin (C), Catechin 3-gallate (Cg), Epicatechin 3-gallate (ECg), Epicatechins (Epicatechin (EC)), epigallocatechin, Epigallocatechin (EGC), Epigallocatechin 3-gallate (EGCg), Gallocatechin (GC), Gallocatechin 3-gallate (GCg)), Gamma amino butyric acid, Genistein, Ginkgo biloba , Ginsenosides, Quercetin, Quercitrin, or Rutin.

15 . The composition of claim 1 , comprising Cannabichromene and at least one purified terpene chosen from Linalool, Borneol, Elemene, Mycerne, Nerolidol, Phytol, Terpinolene, Bornyl acetate, Terpineol.

16 . The composition of claim 1 , comprising Cannabigerol and at least one purified terpene chosen from Linalool, Borneol, elemene, Mycerne, Nerolidol, Phytol, Terpinolene, Bornyl acetate, Terpineol.

17 . The composition of claim 1 , comprising Cannabinol and at least one compound chosen from Linalool, Borneol, elemene, Mycerne, Nerolidol, Phytol, Terpinolene, Bornyl acetate, Terpineol.

18 . The composition of claim 1 , comprising Tetrahydrocannabivarin and at least one compound chosen from Pinene, Bornyl acetate, Limonene, Caryophyllene, and Sabinene.

19 . The composition of claim 1 , comprising a cannabinoid chosen from Tetrahydrocannabinol and Cannabichromene and at least one compound chosen from Caryophyllene, Pinene, Bornyl acetate, Cineole, Limonene, Caryophyllene, Pinene, Bornyl acetate.

20 . The composition of claim 1 , comprising a cannabinoid chosen from Tetrahydrocannabinol or Tetrahydrocannabivarin and at least one compound chosen from Limonene and Caryophyllene.

21 . The composition of claim 1 , comprising a cannabinoid chosen from Tetrahydrocannabinol or Tetrahydrocannabivarin and at least one compound chosen from Limonene, Terpinolene, Pulegone.

22 . The compound of claim 1 , comprising Cannabichromene and at least one compound chosen from Linalool, Myrcene, Terpineol.

23 . The compound of claim 1 , comprising Cannabigerol and Myrcene.

24 . The compound of claim 1 , comprising Cannabidiol and Myrcene.

25 . The compound of claim 1 , comprising Cannabinol and at least one compound chosen from Linalool, Terpineol.

26 . The compound of claim 1 , comprising Tetrahydrocannabivarin and at least one compound chosen from Cineole, Pinene, Bornyl acetate, Limonene, Caryophyllene, and Sabinene.

27 . The compound of claim 1 , comprising at least one cannabinoid chosen from Tetrahydrocannabinol or Cannabidiol and at least one terpene chosen from Caryophyllene, Pinene, Bornyl acetate, Cineole, Limonene, Pulegone, Linalool, Hypericin, Pseudohypericin, Hyperforin, Anethole.

28 . The compound of claim 1 , comprising Tetrahydrocannabinol or Tetrahydrocannabivarin and at least one compound chosen from Pulegone, Cineole, Anethole.

29 . The compound of claim 1 , comprising Tetrahydrocannabinol and Myrcene.

30 . The compound of claim 1 , comprising Tetrahydrocannabivarin and Myrcene.

Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 15, 2019
From: EBBU INC.
To: CANOPY GROWTH CORPORATION
Reel/Frame 048608/0102 →
CERTIFICATES OF CONVERSION AND INCORPORATION Recorded Oct 31, 2018
From: EBBU LLC
To: EBBU INC
Reel/Frame 047902/0124 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 20, 2016
From: WENDSCHUH, MICHAEL VICTOR; COOPER, JONATHAN MICHAEL; DENICOLA, CHRISTOPHER JARRAD; LEVY, KURT ARON; STRICKLER, JON ERIK
To: EBBU, LLC
Reel/Frame 038335/0913 →