Microcapsules containing an oxidizable active, and a process for preparing the same
Disclosed is a microcapsule including a core having an oxidizable active (OA), the outer part of said core being in a solid form, and a water insoluble coating obtained from an encapsulating agent (EA), with the coating surrounding said core. In particular, the EA can be water soluble or organic solvent soluble, in particular in ethanol. The microcapsule can also include an EA in which the water solubility is pH-dependent. Also, the core does not contain a metal oxide, and the coating does not include a disintegrant, such as sodium starch glycolate. Also disclosed is a process for preparing the microcapsules.
1. A microcapsule consisting of:
a single core consisting of an oxidizable active (OA), and at least one additional element selected from drying agents, antioxidant agents, filmogen agents and emulsifying agents, the outer part of said core being in a solid form; and
a water insoluble coating obtained from a water soluble encapsulating agent (EA) selected from alginates of monovalent cations, water insolubility being induced by a salt having a divalent metallic cation, said coating surrounding said core,
wherein said OA is selected from the group consisting of vitamin B5, vitamin B6, vitamin B8, vitamin B9, vitamin A, vitamin D3, vitamin K and vitamin E,
with the proviso that:
said core does not comprise a metal oxide, and
said coating does not comprise a disintegrant.
2. The microcapsule according to claim 1 , wherein said coating is such that, when said microcapsule is placed in an alimentary, cosmetically or pharmaceutically acceptable medium:
said OA is not degraded by element(s) of said medium; and
said element(s) of the medium is (are) not degraded by said OA.
3. The microcapsule according to claim 1 , wherein the mass of said coating is within the range of from 3% to 50% of the total mass of said microcapsule.
4. The microcapsule according to claim 1 , wherein said microcapsule size is in the range of from fpm to 3 mm.
5. The microcapsule according to claim 1 , wherein said OA is in a crystalline state.
6. The microcapsule according to claim 1 , wherein said OA is in an amorphous state.
7. The microcapsule according to claim 1 , wherein said water soluble EA is selected from Na+ alginates or K+ alginates.
8. The microcapsule according to claim 7 , wherein said divalent metallic cation is Ca 2+ or Mg 2+ .
9. The microcapsule according to claim 7 , wherein said salt for inducing water insolubility is CaCl 2 or MgCl 2 .
10. The microcapsule according to claim 1 , wherein the mass of said coating is within the range of from 5% to 8% of the total mass of said microcapsule.
11. The microcapsule according to claim 1 , wherein said microcapsule size is in the range of from 50 μm to 200 μm.
12. The microcapsule according to claim 1 , wherein said microcapsule, wherein:
the drying agent is selected from the group consisting of starch, maltodextrin, protein, caseinate, gelatin, vegetable protein, soya protein, wheat protein, pea protein, gums, and acacia gum;
the antioxidant agent is selected from the group consisting of sodium ascorbate, ascorbyl palmitate, vitamin E, and tocopherol acetate;
the filmogen agent is selected from the group consisting of proteins, caseinate, gums, and cellulose derivatives; and
the emulsifying agent is selected from the group consisting of lecithin, proteins, hydrolyzed proteins, and modified starch.
13. The microcapsule according to claim 1 , wherein the at least one additional element is modified starch and carboxymethylcellulose.
14. A microcapsule according to claim 1 , consisting of:
a single core consisting of an oxidizable active (OA) and at least one additional element selected from the group consisting of: drying agents, antioxidant agents selected from the group consisting of ascorbyl palmitate, vitamin E, and tocopherol acetate, filmogen agents, and emulsifying agents, the outer part of said core being in a solid form; and
a water insoluble coating obtained from a water soluble encapsulating agent (EA) selected from alginates of monovalent cations, water insolubility being induced by a salt having a divalent metallic cation, said coating surrounding said core,
wherein said OA is vitamin C,
with the proviso that:
said core does not comprise a metal oxide, and
said coating does not comprise a disintegrant.
15. The microcapsule according to claim 14 , wherein said vitamin C is natural vitamin C, synthetic vitamin C, a salt of L-ascorbic acid, or a fruit juice comprising vitamin C.
16. The microcapsule according to claim 14 , wherein said alginates of monovalent cations is Na+ alginates or K+ alginates.