IP Library › Patent Application 15076140
Patent Application
App. No. 15/076,140

Attenuated Mannheimia haemolytica

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Quick Facts
Patent No.
US None
App. No.
15/076,140
Abstract

This disclosure provides attenuated M. haemolytica strains useful for providing immunity against M. haemolytica.

Claims (5)

1 . A deletion mutant M. haemolytica bacterium comprising a deletion with the LktCA gene locus encoding acylase (LktC) and leukotoxin A (LktA).

2 . The deletion mutant M. haemolytica bacterium of claim 1 , which is an M. haemolytica serotype A1 bacterium.

3 . The deletion mutant M. haemolytica bacterium of claim 2 , which secretes a truncated form of the LktA protein having an amino acid sequence encoded by the nucleic acid sequence set forth in SEQ ID NO:8 or SEQ ID NO:9.

4 . The deletion mutant M. haemolytica bacterium of claim 1 , which is an M. haemolytica serotype A6 bacterium.

5 . The deletion mutant M. haemolytica bacterium of claim 4 , which secretes a truncated form of the LktA protein having an amino acid sequence encoded by the nucleic acid sequence set forth in SEQ ID NO:8 or SEQ ID NO:9.

Assignments (1)
CONFIRMATORY ASSIGNMENT Recorded Aug 2, 2016
From: BRIGGS, ROBERT E.; TATUM, FRED M.
To: THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE
Reel/Frame 039549/0486 →