IP Library › Granted Patent US 9,849,156
Granted Patent B2
US 9,849,156 · App. 15/080,089 · Granted Dec 26, 2017

Treatment and diagnosis of inflammatory disorders and HIV

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Quick Facts
Patent No.
US 9,849,156
App. No.
15/080,089
Granted
Dec 26, 2017
Kind
B2
Abstract

This invention concerns compositions and methods of treating or diagnosing inflammatory disorders and other disorders, as well as compositions and methods of treating HIV.

Claims (2)

1. A method of treating an inflammatory autoimmune rheumatoid arthritis consisting essentially of administering to a subject in need thereof a therapeutically effective amount of a leukotoxin consisting essentially of SEQ ID NO: 1, wherein the inflammatory autoimmune rheumatoid arthritis is characterized by activation of leukocytes that express upregulated and activated leukocyte function antigen (LFA-1) on their surface to which the leukotoxin specifically binds.

2. The method of claim 1 , wherein the leukotoxin is prepared from Aggregatibacter actinomycetemcomitans Aggregatibacter actinomycetemcomitans.

Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 24, 2024
From: ACTINOBAC BIOMED, INC.
To: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
Reel/Frame 067213/0348 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 18, 2017
From: BELINKA, BENJAMIN
To: ACTINOBAC BIOMED, INC.
Reel/Frame 043333/0243 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 2, 2016
From: KACHLANY, SCOTT, DR.
To: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
Reel/Frame 038438/0790 →