METHOD AND SYSTEM FOR DETERMINIG TREATMENTS BY MODIFYING PATIENT-SPECIFIC GEOMETRICAL MODELS
Systems and methods are disclosed for evaluating cardiovascular treatment options for a patient. One method includes creating a three-dimensional model representing a portion of the patient's heart based on patient-specific data regarding a geometry of the patient's heart or vasculature; and for a plurality of treatment options for the patient's heart or vasculature, modifying at least one of the three-dimensional model and a reduced order model based on the three-dimensional model. The method also includes determining, for each of the plurality of treatment options, a value of a blood flow characteristic, by solving at least one of the modified three-dimensional model and the modified reduced order model; and identifying one of the plurality of treatment options that solves a function of at least one of: the determined blood flow characteristics of the patient's heart or vasculature, and one or more costs of each of the plurality of treatment options.
1 - 28 . (canceled)
29 . A system for evaluating one or more treatment options for a patient, the system comprising:
at least one computer system configured for:
receiving a three-dimensional model representing at least a portion of the patient's anatomy;
determining a computational model associated with the received three-dimensional model;
determining a blood flow characteristic solved from the determined computational model;
determining an objective function of the blood flow characteristic solved from the determined computational model, the objective function designed to maximize or minimize the determined blood flow characteristic; and
selecting a treatment option by solving the determined objective function.
30 . The system of claim 29 , wherein the blood flow characteristic includes arterial flow, blood pressure change, fractional flow reserve loss, or a combination thereof.
31 . The system of claim 29 , wherein the computer system is configured for:
determining a local blood flow characteristic and a global blood flow characteristic; and
selecting the treatment option using the determined local blood flow characteristic or the determined global blood flow characteristic.
34 . The system of claim 29 , wherein the computer system is configured for:
receiving monetary cost information, patient information, treatment information, or a combination thereof associated with each treatment option of a plurality of treatment options including the treatment option; and
selecting the treatment option out of the plurality of treatment options based, at least in part, on the monetary cost information, patient information, treatment information, or a combination thereof associated with each of the treatment options of the plurality of treatment options.
35 . The system of claim 29 , wherein the computer system is configured for:
determining the objective function based on the number of or distance between stents, grafts, bifurcations, or interventions.
36 . The system of claim 29 , wherein the computer system is configured for:
determining the treatment option that solves the objective function based on vessel size.
37 . The system of claim 29 , wherein the treatment option includes a number, location, or combination of one or more stents, grafts, bifurcations, or interventions.
38 . The system of claim 29 , wherein the computer system is further configured for:
displaying the three-dimensional model as modified based on the selected treatment option.
39 . A computer-implemented method for evaluating one or more treatment options for a patient, the method comprising:
receiving a three-dimensional model representing at least a portion of the patient's anatomy;
determining a computational model associated with the received three-dimensional model;
determining a blood flow characteristic solved from the determined computational model;
determining an objective function of the blood flow characteristic solved from the determined computational model, the objective function designed to maximize or minimize the determined blood flow characteristic; and
selecting a treatment option by solving the determined objective function.
40 . The computer-implemented method of claim 39 , wherein the blood flow characteristic includes arterial flow, blood pressure change, fractional flow reserve loss, or a combination thereof.
41 . The computer-implemented method of claim 39 , further comprising:
determining a local blood flow characteristic and a global blood flow characteristic; and
selecting the treatment option using the determined local blood flow characteristic or the determined global blood flow characteristic.
42 . The computer-implemented method of claim 39 , further comprising:
receiving monetary cost information, patient information, treatment information, or a combination thereof associated with each treatment option of a plurality of treatment options including the treatment option; and
selecting the treatment option out of the plurality of treatment options based, at least in part, on the monetary cost information, patient information, treatment information, or a combination thereof associated with each of the treatment options of the plurality of treatment options.
43 . The computer-implemented method of claim 39 , further comprising:
determining the objective function based on the number of or distance between stents, grafts, bifurcations, or interventions.
44 . The computer-implemented method of claim 39 , further comprising:
determining the treatment option that solves the objective function based on vessel size.
45 . The computer-implemented method of claim 39 , wherein the treatment option includes a number, location, or combination of one or more stents, grafts, bifurcations, or interventions.
46 . The computer-implemented method of claim 39 , further comprising:
displaying the three-dimensional model as modified based on the selected treatment option.
47 . A non-transitory computer readable medium for use on a computer system containing computer-executable programming instructions for evaluating one or more treatment options for a patient, the method comprising:
receiving a three-dimensional model representing at least a portion of the patient's anatomy;
determining a computational model associated with the received three-dimensional model;
determining a blood flow characteristic solved from the determined computational model;
determining an objective function of the blood flow characteristic solved from the determined computational model, the objective function designed to maximize or minimize the determined blood flow characteristic; and
selecting a treatment option by solving the determined objective function.
48 . The non-transitory computer readable medium of claim 47 , wherein the blood flow characteristic includes arterial flow, blood pressure change, fractional flow reserve loss, or a combination thereof.
49 . The non-transitory computer readable medium of claim 47 , the method further comprising:
determining a local blood flow characteristic and a global blood flow characteristic; and
selecting the treatment option using the determined local blood flow characteristic or the determined global blood flow characteristic.
50 . The non-transitory computer readable medium of claim 47 , the method further comprising:
receiving monetary cost information, patient information, treatment information, or a combination thereof associated with each treatment option of a plurality of treatment options including the treatment option; and
selecting the treatment option out of the plurality of treatment options based, at least in part, on the monetary cost information, patient information, treatment information, or a combination thereof associated with each of the treatment options of the plurality of treatment options.