IP Library Granted Patent US 9,592,004
Granted Patent B2
US 9,592,004 · App. 15/082,957 · Granted Mar 14, 2017

Methods and systems for managing epilepsy and other neurological disorders

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Quick Facts
Patent No.
US 9,592,004
App. No.
15/082,957
Granted
Mar 14, 2017
Kind
B2
Abstract

The present invention provides systems and methods for managing epilepsy. In one embodiment, a method of the present invention characterize a patient's propensity for a future epileptic seizure and communicates to the patient and/or a health care provider a therapy recommendation. The therapy recommendation is typically a function of the patient's propensity for the future epileptic seizure.

Claims (37)

1. A method of monitoring a patient, the method comprising:

using a processor to evaluate a first physiological signal received from the patient indicative of a first patient status regarding an onset of a first neurological event;

using the processor to provide a therapy recommendation, wherein the therapy recommendation is selected from a plurality of therapy recommendations based on the first patient status regarding the onset of the first neurological event;

using the processor to evaluate a second physiological signal received from the patient indicative of a second patient status regarding an onset of a second neurological event that is subsequent to the first neurological event, the second physiological signal being different from the first physiological signal; and

transmitting to a communications assembly an alert, wherein the alert is selected from a plurality of alerts based on the second patient status regarding the onset of the second neurological event.

2. The method of claim 1 , wherein the using of the processor to evaluate the second physiological signal includes evaluating an effectiveness of a therapy applied in response to the therapy recommendation.

3. The method of claim 1 , wherein at least one of the first patient status and the second patient status is based on a heart rate signal of the patient.

4. The method of claim 3 , wherein the using of the processor to evaluate the second physiological signal includes evaluating an effectiveness of a therapy applied in response to the therapy recommendation.

5. The method of claim 1 , further comprising administering a therapy to the patient in response to the therapy recommendation.

6. The method of claim 5 , wherein the transmitting to the communications assembly the alert includes transmitting at least one alert indicative of an effectiveness of the therapy.

7. The method of claim 1 , further comprising:

using the processor to evaluate a third physiological signal received from the patient indicative of a third patient status regarding an onset of a third neurological event that is subsequent to the second neurological event, the third physiological signal being different from the second physiological signal; and

transmitting to the communications assembly another alert, wherein the another alert is selected from the plurality of alerts based on the third patient status regarding the onset of the third neurological event.

8. The method of claim 7 , wherein the using of the processor to evaluate the second and/or third physiological signals includes evaluating an effectiveness of a therapy applied in response to the therapy recommendation.

9. The method of claim 7 , wherein at least one of the first patient status, the second patient status, and the third patient status is based on a heart rate signal of the patient.

10. The method of claim 9 , wherein the using of the processor to evaluate the second and/or third physiological signals includes evaluating an effectiveness of a therapy applied in response to the therapy recommendation.

11. The method of claim 1 , further comprising determining stimulation parameters to apply using the response and applying stimulation using the implanted device using the determined stimulation parameters.

12. A method of monitoring a patient, the method comprising:

using a processor to evaluate a first physiological signal received from the patient indicative of a first neurological event;

administering an initial therapy to the patient in response to the first neurological event;

using the processor to evaluate a second physiological signal subsequent to the administering of the initial therapy, the second physiological signal indicative of a second neurological event comprising a continuation of at least a portion of the first neurological event; and

transmitting to a communications assembly an alert, wherein the alert is selected from a plurality of alerts based on at least one of the first neurological event and the second neurological event.

13. The method of claim 11 , wherein the continuation of at least a portion of the first neurological event is at least one of an increased heart rate and a seizure movement.

14. The method of claim 11 , further comprising administering a second therapy to the patient subsequent to the initial therapy, wherein the second therapy is a modification of the initial therapy based on the second neurological event.

15. The method of claim 11 , wherein the alert is indicative of an effectiveness of the initial therapy.

16. A method of monitoring a patient, the method comprising:

using a processor to evaluate a first physiological signal received from the patient indicative of a first patient status regarding an onset of a first neurological event;

using the processor to provide a therapy recommendation, wherein the therapy recommendation is selected from a plurality of therapy recommendations based on the first patient status regarding the onset of the first neurological event;

using the processor to evaluate a second physiological signal received from the patient indicative of a second patient status regarding an onset of a second neurological event that is subsequent to the first neurological event, the second physiological signal being different from the first physiological signal;

determining stimulation parameters to apply using a response; and

applying stimulation using the implanted device using the determined stimulation parameters to apply a first therapy.

17. The method of claim 15 , wherein the using of the processor to evaluate the second physiological signal includes evaluating an effectiveness of a therapy applied in response to the therapy recommendation.

18. The method of claim 15 , wherein at least one of the first patient status and the second patient status is based on a heart rate signal of the patient.

19. The method of claim 15 , further comprising transmitting to a communications assembly an alert, wherein the alert is selected from a plurality of alerts based on the second patient status regarding the onset of the second neurological event.

20. The method of claim 15 , further comprising:

using the processor to evaluate a third physiological signal received from the patient indicative of a third patient status regarding an onset of a third neurological event that is subsequent to the second neurological event, the third physiological signal being different from the second physiological signal; and

administering a second therapy to the patient, wherein the second therapy is a modification of the first therapy based on the third patient status regarding the onset of the third neurological event.

Assignments (10)
RELEASE OF SECURITY INTEREST Recorded Sep 20, 2021
From: ACF FINCO I LP
To: LIVANOVA USA, INC.
Reel/Frame 057552/0378 →
RELEASE OF SECURITY INTEREST Recorded Aug 16, 2021
From: ARES CAPITAL CORPORATION, AS AGENT FOR THE LENDERS
To: LIVANOVA USA, INC.
Reel/Frame 057189/0001 →
SECURITY INTEREST Recorded Aug 16, 2021
From: LIVANOVA USA, INC.
To: GOLDMAN SACHS BANK USA, AS COLLATERAL AGENT
Reel/Frame 057188/0001 →
PATENT SECURITY AGREEMENT Recorded Dec 30, 2020
From: LIVANOVA USA, INC.
To: ACF FINCO I LP, AS COLLATERAL AGENT
Reel/Frame 054881/0784 →
CHANGE OF NAME Recorded Jun 29, 2020
From: CYBERONICS, INC.
To: LIVANOVA USA, INC.
Reel/Frame 053306/0229 →
PATENT SECURITY AGREEMENT Recorded Jun 17, 2020
From: LIVANOVA USA, INC.
To: ARES CAPITAL CORPORATION, AS COLLATERAL AGENT
Reel/Frame 053673/0675 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 18, 2016
From: DILORENZO, DANIEL J.; LEYDE, KENT W.
To: BIONEURONICS CORPORATION
Reel/Frame 040048/0097 →
CHANGE OF NAME Recorded Oct 18, 2016
From: BIONEURONICS CORPORATION
To: NEUROVISTA CORPORATION
Reel/Frame 040415/0460 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 18, 2016
From: NEUROVISTA CORPORATION
To: CYBERONICS, INC.
Reel/Frame 040048/0393 →
SECURITY INTEREST Recorded Oct 18, 2016
From: NEUROVISTA CORPORATION
To: CYBERONICS, INC.
Reel/Frame 040048/0126 →