Systems and methods for determining and visualizing a functional relationship between a vascular network and perfused tissue

1. A computer-implemented method of creating an interactive tool for determining and displaying a functional relationship between a vascular network and an associated perfused tissue, the method comprising:

receiving a patient-specific vascular model of a patient's anatomy;

receiving a patient-specific tissue model of the patient's anatomy, the patient-specific tissue model describing a tissue supplied at least in part with blood through vasculature described by the patient-specific vascular model;

generating a user interface comprising a display of at least a portion of the patient-specific vascular model and a display of at least a portion of the patient-specific tissue model;

receiving, via the user interface, a selection of a first region, the first region being a region of one of the patient-specific vascular model and the patient-specific tissue model; and

upon receiving the selection of the first region,

determining a second region having a blood supply relationship with the first region, the second region being a region of another of the patient-specific vascular model and the patient-specific tissue model, and

displaying the second region in a manner indicating that the second region has the blood supply relationship with the first region.

2. The computer-implemented method of claim 1 , wherein

the first region is a region of the patient-specific vascular model and represents a region of the vasculature,

the second region is a region of the patient-specific tissue model, and

the blood supply relationship is a relationship in which the second region represents a region, of the tissue, that is supplied by blood passing through the region of the vasculature represented by the first region.

3. The computer-implemented method of claim 1 , wherein the display of the at least the portion of the patient-specific tissue model includes a geometrical model of the patient-specific tissue model, or a “bulls-eye” model of the patient-specific tissue model.

4. The computer-implemented method of claim 1 , further comprising:

receiving or determining an association between a region of the patient-specific vascular model and a region of the patient-specific tissue model,

wherein the association is based on the region of the patient-specific tissue model being at least a portion of a perfusion territory of the location of the patient-specific vascular model.

5. The computer-implemented method of claim 1 , wherein the patient-specific vascular model includes coronary, carotid, cerebral, peripheral, renal, and/or visceral vasculature.

6. The computer-implemented method of claim 1 , wherein the patient-specific tissue model includes myocardial, brain, muscle, kidney, bowel, liver, and/or spleen tissue.

7. The computer-implemented method of claim 1 , wherein

the method further comprises generating a user interface comprising a display of at least a portion of the patient-specific vascular model and a display of at least a portion of the patient-specific tissue model, the user interface further displaying a recommendation of at least one region of the display of the patient-specific vascular model within the generated user interface to be selected by a user or of the display of the patient-specific tissue model within the generated user interface to be selected by a user,

the recommendation indicates severe or significant trouble areas of the patient-specific tissue model or the patient-specific vascular model, and

the at least one region includes the first region.

8. The computer-implemented method of claim 1 , wherein

the first region is a region of the patient-specific tissue model and represents a region of the tissue,

the second region is a region of the patient-specific vascular model, and

the blood supply relationship is a relationship in which the second region represents a region, of the vasculature, that supplies by blood to the region of the tissue represented by the first region.

9. A system for creating an interactive tool for determining and displaying a functional relationship between a vascular network and an associated perfused tissue, the system comprising:

a data storage device storing instructions for creating an interactive tool for determining and displaying a functional relationship between a vascular network and an associated perfused tissue; and

a processor configured to execute the instructions to perform a method including:

receiving a patient-specific vascular model of a patient's anatomy;

receiving a patient-specific tissue model of the patient's anatomy, the patient-specific tissue model describing a tissue supplied at least in part with blood through vasculature described by the patient-specific vascular model;

generating a user interface comprising a display of at least a portion of the patient-specific vascular model and a display of at least a portion of the patient-specific tissue model;

receiving, via the user interface, a selection of a first region, the first region being a region of one of the patient-specific vascular model and the patient-specific tissue model; and

upon receiving the selection of the first region,

determining a second region having a blood supply relationship with the first region, the second region being a region of another of the patient-specific vascular model and the patient-specific tissue model, and

displaying the second region in a manner indicating that the second region has the blood supply relationship with the first region.

10. The system of claim 9 , wherein

the first region is a region of the patient-specific vascular model and represents a region of the vasculature,

the second region is a region of the patient-specific tissue model, and

the blood supply relationship is a relationship in which the second region represents a region, of the tissue, that is supplied by blood passing through the region of the vasculature represented by the first region.

11. The system of claim 9 , wherein the display of the at least the portion of the patient-specific tissue model includes a geometrical model of the patient-specific tissue model, or a “bulls-eye” model of the patient-specific tissue model.

12. The system of claim 9 , wherein the system is further configured for:

receiving or determining an association between a region of the patient-specific vascular model and a region of the patient-specific tissue model,

wherein the association is based on the region of the patient-specific tissue model being at least a portion of a perfusion territory of the location of the patient-specific vascular model.

13. The system of claim 9 , wherein the patient-specific vascular model includes coronary, carotid, cerebral, peripheral, renal, and/or visceral vasculature.

14. The system of claim 9 , wherein the patient-specific tissue model includes myocardial, brain, muscle, kidney, bowel, liver, and/or spleen tissue.

15. The system of claim 9 , the method further comprises generating a user interface comprising a display of at least a portion of the patient-specific vascular model and a display of at least a portion of the patient-specific tissue model, the user interface further displaying a recommendation of at least one region of the display of the patient-specific vascular model within the generated user interface to be selected by a user or of the display of the patient-specific tissue model within the generated user interface to be selected by a user,

the recommendation indicates severe or significant trouble areas of the patient-specific tissue model or the patient-specific vascular model, and

the at least one region includes the first region.

16. The system of claim 9 , wherein, wherein

the first region is a region of the patient-specific tissue model and represents a region of the tissue,

the second region is a region of the patient-specific vascular model, and

the blood supply relationship is a relationship in which the second region represents a region, of the vasculature, that supplies by blood to the region of the tissue represented by the first region.

17. A non-transitory computer readable medium for use on a computer system containing computer-executable programming instructions for performing a method of creating an interactive tool for determining and displaying a functional relationship between a vascular network and an associated perfused tissue, the method comprising:

receiving a patient-specific vascular model of a patient's anatomy;

receiving a patient-specific tissue model of the patient's anatomy, the patient-specific tissue model describing a tissue supplied at least in part with blood through vasculature described by the patient-specific vascular model;

generating a user interface comprising a display of at least a portion of the patient-specific vascular model and a display of at least a portion of the patient-specific tissue model;

receiving, via the user interface, a selection of a first region, the first region being a region of one of the patient-specific vascular model and the patient-specific tissue model; and

upon receiving the selection of the first region,

determining a second region having a blood supply relationship with the first region, the second region being a region of another of the patient-specific vascular model and the patient-specific tissue model, and

displaying the second region in a manner indicating that the second region has the blood supply relationship with the first region.

18. The non-transitory computer readable medium of claim 17 , wherein

the first region is a region of the patient-specific vascular model and represents a region of the vasculature,

the second region is a region of the patient-specific tissue model, and

the blood supply relationship is a relationship in which the second region represents a region, of the tissue, that is supplied by blood passing through the region of the vasculature represented by the first region.

19. The non-transitory computer readable medium of claim 17 , wherein the display of the at least the portion of the patient-specific tissue model includes a geometrical model of the patient-specific tissue model, or a “bulls-eye” model of the patient-specific tissue model.

20. The non-transitory computer readable medium of claim 17 , wherein

the first region is a region of the patient-specific tissue model and represents a region of the tissue,

the second region is a region of the patient-specific vascular model, and

the blood supply relationship is a relationship in which the second region represents a region, of the vasculature, that supplies by blood to the region of the tissue represented by the first region.