IP Library Granted Patent US 10,016,125
Granted Patent B2
US 10,016,125 · App. 15/091,615 · Granted Jul 10, 2018

Apparatus for modelling ocular structures

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Quick Facts
Patent No.
US 10,016,125
App. No.
15/091,615
Granted
Jul 10, 2018
Kind
B2
Abstract

An apparatus for motion compensated modelling of a parameter of an eye, comprising: a first measuring means for measuring a plurality of position parameters of the eye with respect to an optical reference coordinate system of the apparatus; a second measuring means for measuring an interference signal at a plurality of optical reference coordinates, wherein the measurement of the plurality of position parameters and measurement of the interference signal are time synchronized; means for correcting the interference signal to account for a displacements of a parameter of the plurality of position parameters; and means for modelling the eye parameter based at least in part on the corrected interference signal.

Claims (19)

1. A method for motion compensated modelling of a parameter of an eye, comprising:

illuminating a targeted ocular surface with a least one incident light beam and directing at least two light beams returning from the illuminated targeted ocular surface to an image forming device;

measuring a plurality of position parameters of the eye with respect to an optical reference coordinate system of the apparatus based on an image formed in the image forming device;

directing an OCT imaging beam at the targeted ocular surfaces;

measuring an interference signal associated with the OCT imaging beam at a plurality of optical reference coordinates, wherein the measurement of the plurality of position parameters and measurement of the interference signal are time synchronized;

correcting the interference signal to account for a displacement of a parameter of the plurality of position parameters; and

modelling the eye parameter based at least in part on the corrected interference signal.

2. The method according to claim 1 wherein the plurality of position parameters comprise one or more of: lateral displacement along an x axis of the optical reference coordinate system, lateral displacement along a y axis of the optical reference coordinate system, axial displacement along a z axis of the optical reference coordinate system, cyclorotation around the z-axis, rotation around the x axis, and rotation around the y axis.

3. The method of claim 1 further comprising: interpolating between measurements of the plurality of position parameters.

4. The method of claim 1 further comprising: determining a reference location associated with the interference signal and correcting said reference location based on the measured position parameters.

5. The method of claim 1 further comprising: correcting an optical path length based on a difference in an optical path length between an off-axis ray-traced path length and a path length along the z axis of the optical reference coordinate system.

6. The method of claim 1 further comprising: measuring a position parameter based on a retinal reflex.

7. The method according to claim 5 further comprising: iteratively correcting the optical path length.

8. The method of claim 1 wherein the ocular surface comprises one or more of: anterior corneal surface, a posterior corneal surface, an anterior lens surface, a posterior lens surface or a retinal surface.

9. The method of claim 1 further comprising: determining refraction at the ocular surface and correcting the modelled eye parameter based on the determined refraction.

10. A computer readable programmable medium carrying a computer program stored thereon which when executed by a processing module implements the method of claim 1 .

11. The method of claim 9 wherein correcting the interference signal to account for a displacement of a parameter of the plurality of position parameters further comprises:

correcting for an optical path difference associated with the interference signal using the determined refraction.

12. The method of claim 1 wherein the formed image comprises one or both of: Purkinje reflections and a detected anatomical feature.

Assignments (4)
CONFIRMATORY DEED OF ASSIGNMENT EFFECTIVE APRIL 8, 2019 Recorded Dec 10, 2019
From: NOVARTIS AG
To: ALCON INC.
Reel/Frame 051454/0788 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 21, 2018
From: ZAKHAROV, PAVEL; BOSS, DANIEL; MROCHEN, MICHAEL; NOLAN, ANDREW
To: CLEARSIGHT INNOVATIONS LIMITED
Reel/Frame 047618/0722 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 6, 2016
From: CLEARSIGHT INNOVATIONS LIMITED
To: ALCON PHARMACEUTICALS, LIMITED
Reel/Frame 038201/0675 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 6, 2016
From: ALCON PHARMACEUTICALS, LIMITED
To: NOVARTIS AG
Reel/Frame 038201/0696 →