IP Library Granted Patent US 10,907,192
Granted Patent B2
US 10,907,192 · App. 15/093,236 · Granted Feb 2, 2021

Systems and methods for artificial test strip controls

Inventors: Gary L. Hughes (Camby, IN); Aniruddha Patwardhan (Fishers, IN); Keith Moskowitz (Indianapolis, IN)
Assignee: POLYMER TECHNOLOGY SYSTEMS, INC.
C12Q1/60G01N21/78G01N21/8483G01N33/523G01N33/96G01N2021/7759G01N2496/00
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Quick Facts
Patent No.
US 10,907,192
App. No.
15/093,236
Granted
Feb 2, 2021
Kind
B2
Abstract

A linearity standard includes a plurality of calibration solutions, each calibration solution having a different level of a reactant having a known response in a test strip and meter combination, and an electronic storage medium for storing calibration instructions and known responses for each solution of the plurality of calibration solutions.

Claims (10)

1. A method of calibrating a meter and a test strip combination, comprising:

contacting the test strip with a calibration solution;

measuring a detectable property of the test strip with the meter, the meter being an optical meter, wherein the detectable property is a first reflectance; and

adjusting calibration of the meter for lots of test strips associated with the test strip based on the detectable property and an expected detectable property wherein the calibration solution includes potassium ferricyanide and the potassium ferricyanide reacts with a chromophore used in the test strip to produce a color change which is measured as the first reflectance, and the expected detectable property is a second reflectance corresponding to a reflectance expected from a concentration of the potassium ferricyanide in the calibration solution and wherein the potassium ferricyanide only reacts with the chromophore.

2. The method of claim 1 , wherein the meter and the test strip combination tests for total cholesterol.

3. The method of claim 1 , wherein the meter and test strip combination tests for one or more analytes selected from the list consisting of HDL cholesterol, LDL cholesterol, triglycerides, total cholesterol, and glucose.

4. The method of claim 1 , wherein the test strip includes a plurality of separation layers, and the calibration solution does not interact with the plurality of separation layers.

5. The method of claim 1 , wherein the calibration solution includes a plurality of linearity controls, the plurality of linearity controls including solutions containing different levels of potassium ferricyanide, such that generate different responses by the meter.

6. The method of claim 1 , wherein the calibration solution does not include serum.

7. The method of claim 1 , wherein the calibration solution is stable at room temperature.

Assignments (3)
RELEASE OF SECURITY INTEREST Recorded Jan 26, 2023
From: PNC BANK, NATIONAL ASSOCIATION, AS AGENT
To: POLYMER TECHNOLOGY SYSTEMS, INC.
Reel/Frame 062515/0001 →
SECURITY INTEREST Recorded Jul 26, 2016
From: POLYMER TECHNOLOGY SYSTEMS, INC.
To: PNC BANK, NATIONAL ASSOCIATION, AS AGENT
Reel/Frame 039472/0762 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 21, 2016
From: HUGHES, GARY L.; PATWARDHAN, ANIRUDDHA; MOSKOWITZ, KEITH
To: POLYMER TECHNOLOGY SYSTEMS, INC.
Reel/Frame 038340/0680 →
Continuity (2)
Provisional Application 62144233 · Apr 7, 2015
Related Publication 20160298170A1 · Oct 13, 2016