IP Library Granted Patent US 9,980,678
Granted Patent B2
US 9,980,678 · App. 15/096,146 · Granted May 29, 2018

Psychological acute stress measurement using a wireless sensor

Inventors: Alexander Chan (Campbell, CA); Ravi Narasimhan (Sunnyvale, CA); Nandakumar Selvaraj (San Jose, CA); Toai Doan (Saratoga, CA)
Assignee: VITAL CONNECT, INC.
A61B5/4884A61B5/0006A61B5/02055A61B5/02405A61B5/0456A61B5/0468A61B5/08A61B5/1117A61B5/1118A61B5/165A61B5/7235A61B5/021A61B5/0245A61B5/02116A61B5/02416A61B5/1116A61B5/1123
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Quick Facts
Patent No.
US 9,980,678
App. No.
15/096,146
Granted
May 29, 2018
Kind
B2
Abstract

A method and system for determining psychological acute stress are disclosed. In a first aspect, the method comprises detecting a physiological signal using a wireless sensor device, determining a stress feature using a normalized heart rate and a plurality of heart rate variability (HRV) features, wherein the normalized heart rate and the plurality of heart rate variability features are calculated using the detected physiological signal, and determining a stress level using the stress feature to determine the psychological acute stress. In a second aspect, the system comprises a wireless sensor device that includes a processor and a memory device coupled to the processor, wherein the memory device stores an application which, when executed by the processor, causes the wireless sensor device to carry out the steps of the method.

Claims (55)

1. A method for determining psychological acute stress, the method comprising:

detecting a physiological signal using a wireless sensor device;

calculating a normalized heart rate using the detected physiological signal by combining a continuous basal heart rate and an average heart rate using the equation: HRR=(HR−HR b )/(HR max −HR b ), wherein the HR b is the continuous basal heart rate, the HR is the average heart rate, and the HR max =(208−0.7*Age) or (220−Age);

calculating a plurality of heart rate variability (HRV) features using the detected physiological signal

determining a stress feature using the normalized heart rate and the plurality of heart rate variability (HRV) features,

wherein the plurality of HRV features include statistical HRV features, frequency-domain HRV features, and non-linear HRV features,

wherein the frequency-domain HRV features include a ratio of spectral band powers (LF/HF ratio), and

wherein the non-linear HRV features include an approximate entropy measuring complexity of HR time interval series data of the physiological signal; and

determining a stress level using the stress feature to determine the psychological acute stress.

2. The method of claim 1 , wherein the statistical HRV features include any of a standard deviation of HR intervals (SDNN) and a root mean square successive differences of HR intervals (RMSSD), wherein the frequency-domain HRV features further include a normalized spectral band powers, and wherein the non-linear HRV features further include Poincare plot measures.

3. The method of claim 1 , further comprising:

determining whether an activity level threshold is reached; and

wherein if the activity level threshold is reached, detecting another physiological signal prior to the determining of the stress feature.

4. The method of claim 1 , wherein the plurality of HRV features are calculated by:

performing peak detection on the physiological signal to provide a plurality of successive peaks;

calculating a heart rate interval series using the plurality of successive peaks;

removing artifacts from the heart rate interval series to provide pruned heart rate interval values; and

extracting features from the pruned plurality of HRV features to provide the plurality of HRV features.

5. The method of claim 4 , wherein the physiological signal is any of an electrocardiogram (ECG) signal and a photoplethysmogram (PPG) signal.

6. The method of claim 5 , wherein the peak detection detects R peaks of the ECG signal or systolic peaks of the PPG signal.

7. The method of claim 4 , wherein the extracting step further comprises:

determining the continuous basal heart rate using the pruned heart rate interval values;

determining the average heart rate using the pruned heart rate interval values; and

determining the plurality of HRV features using a calculation of the pruned heart rate interval values over a predetermined time period.

8. The method of claim 1 , wherein the determining of the stress level step further comprises:

determining a probability mass function for a detected posture;

calculating the stress level using both the stress feature and the probability mass function; and

providing the stress level as a stress index metric on a predetermined scale.

9. A wireless sensor device for determining psychological acute stress, the wireless sensor device including a processor and a memory device coupled to the processor, wherein the memory device stores an application which, when executed by the processor, causes the wireless sensor device to:

detect a physiological signal using a wireless sensor device;

determine a stress feature using a normalized heart rate and a plurality of heart rate variability (HRV) features, wherein the normalized heart rate and the plurality of HRV features are calculated using the detected physiological signal,

wherein the plurality of HRV features include statistical HRV features, frequency-domain HRV features, and non-linear HRV features,

wherein the frequency-domain HRV features include a ratio of spectral band powers (LF/HF ratio), and

wherein the non-linear HRV features include an approximate entropy measuring complexity of HR time interval series data of the physiological signal; and

determine a stress level including:

determine the psychological acute stress using, the stress feature,

determine a probability mass function for a detected posture,

calculate the stress level using both the stress feature and the probability mass function, and

provide the stress level as a stress index metric on a predetermined scale.

10. The wireless sensor device of claim 9 , wherein the statistical HRV features include any of a standard deviation of HR intervals (SDNN) and a root mean square successive differences of HR intervals (RMSSD), wherein the frequency-domain HRV features include a normalized spectral band powers, and wherein the non-linear HRV features include Poincare plot measures.

11. The wireless sensor device of claim 9 , wherein the processor further causes the wireless sensor device to:

determine whether an activity level threshold is reached; and

wherein if the activity level threshold is reached, detect another physiological signal prior to the determining of the stress feature.

12. The wireless sensor device of claim 9 , wherein the plurality of HRV features are calculated by the processor further causing the wireless sensor device to:

perform peak detection on the physiological signal to provide a plurality of successive peaks;

calculate a heart rate interval series using the plurality of successive peaks;

remove artifacts from the heart rate interval series to provide pruned heart rate interval values; and

extract features from the pruned plurality of HRV features to provide the plurality of HRV features.

13. The wireless sensor device of claim 12 , wherein the physiological signal is any of an electrocardiogram (ECG) signal and a photoplethysmogram (PPG) signal.

14. The wireless sensor device of claim 13 , wherein the peak detection detects R peaks of the ECG signal or systolic peaks of the PPG signal.

15. The wireless sensor device of claim 12 , wherein to extract further comprises to:

determine a continuous basal heart rate using the pruned heart rate interval values;

determine an average heart rate using the pruned heart rate interval values; and

determine the plurality of HRV features using a calculation of the pruned heart rate interval values basal heart rate over a predetermined time period.

16. The wireless sensor device of claim 15 , wherein the calculation of the normalized heart rate comprises combining the continuous basal heart rate and the average heart rate using the equation: HRR=(HR−HR b )/(HR max −HR b ), where HR b is the continuous basal heart rate, HR is the average heart rate, and HR max =(208−0.7*Age) or (220−Age).

Assignments (8)
RELEASE OF SECURITY INTEREST Recorded Jul 5, 2024
From: INNOVATUS LIFE SCIENCES LENDING FUND I, LP
To: VITAL CONNECT, INC.
Reel/Frame 068146/0132 →
SECURITY INTEREST Recorded Jul 5, 2024
From: VITAL CONNECT, INC.
To: TRINITY CAPITAL INC.
Reel/Frame 068146/0160 →
SECURITY INTEREST Recorded Jan 8, 2021
From: VITAL CONNECT, INC.
To: INNOVATUS LIFE SCIENCES LENDING FUND I, LP
Reel/Frame 054941/0651 →
RELEASE OF SECURITY INTEREST Recorded Jan 8, 2021
From: OXFORD FINANCE LLC
To: VITAL CONNECT, INC.
Reel/Frame 054941/0743 →
SECURITY INTEREST Recorded Apr 9, 2020
From: VITAL CONNECT, INC.
To: OXFORD FINANCE LLC
Reel/Frame 052354/0752 →
RELEASE OF SECURITY INTEREST Recorded Oct 5, 2017
From: PERCEPTIVE CREDIT OPPORTUNITIES FUND, L.P.; PERCEPTIVE CREDIT OPPORTUNITIES GP, LLC
To: VITAL CONNECT, INC.
Reel/Frame 043797/0083 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 22, 2016
From: CHAN, ALEXANDER; NARASIMHAN, RAVI; SELVARAJ, NANDAKUMAR; DOAN, TOAI
To: VITAL CONNECT, INC.
Reel/Frame 039825/0714 →
PATENT SECURITY AGREEMENT Recorded Jun 10, 2016
From: VITAL CONNECT, INC.
To: PERCEPTIVE CREDIT OPPORTUNITIES FUND, LP; PERCEPTIVE CREDIT OPPORTUNITIES GP, LLC
Reel/Frame 039012/0547 →
Continuity (2)
Continuation In Part 13664199 · Oct 30, 2012
Related Publication 20160338640A1 · Nov 24, 2016