IP Library Granted Patent US 9,788,778
Granted Patent B2
US 9,788,778 · App. 15/096,163 · Granted Oct 17, 2017

Measuring psychological stress from cardiovascular and activity signals

Inventors: Alexander Chan (Campbell, CA); Ravi Narasimhan (Sunnyvale, CA)
Assignee: Vital Connect, Inc.
A61B5/165A61B5/0006A61B5/0245A61B5/02405A61B5/044A61B5/04012A61B5/0456A61B5/0468A61B5/1116A61B5/1118A61B5/1123A61B5/4884
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Quick Facts
Patent No.
US 9,788,778
App. No.
15/096,163
Granted
Oct 17, 2017
Kind
B2
Abstract

A method and system for measuring psychological stress disclosed. In a first aspect, the method comprises determining R-R intervals from an electrocardiogram (ECG) to calculate a standard deviation of the R-R intervals (SDNN) and determining a stress feature (SF) using the SDNN. In response to reaching a threshold, the method includes performing adaptation to update a probability mass function (PMF). The method includes determining a stress level (SL) using the SF and the updated PMF to continuously measure the psychological stress. In a second aspect, the system comprises a wireless sensor device coupled to a user via at least one electrode, wherein the wireless sensor device includes a processor and a memory device coupled to the processor, wherein the memory device stores an application which, when executed by the processor, causes the processor to carry out the steps of the method.

Claims (58)

1. A method for measuring psychological stress, the method comprising:

determining R-R intervals from an electrocardiogram (ECG) to calculate a standard deviation of the R-R intervals (SDNN), wherein the determining the R-R intervals from the ECG to calculate the SDNN further comprises:

detecting R peaks from a measured ECG within a predetermined time period, and

calculating the R-R intervals using the detected R peaks;

determining a stress feature (SF) using the SDNN, wherein the determining the stress feature (SF) using the SDNN further comprises:

calculating a mean heart rate (HR) from the ECG within the predetermined time period, and

calculating the SF utilizing an algorithm SF=HR+α*SDNN, wherein the α includes a predetermined negative variable that allows for combining the HR and the SDNN;

in response to reaching a threshold, performing adaptation to update a probability mass function (PMF); and

determining a stress level (SL) using the SF and the updated PMF to continuously measure the psychological stress.

2. The method of claim 1 , further comprising:

determining a posture state, wherein the psychological stress is not measured if the posture state is active; and

displaying the determined SL to a user or another device.

3. The method of claim 2 , wherein the posture state includes any of active, sitting, and standing.

4. The method of claim 1 , wherein performing adaptation to update the PMF further comprises:

grouping data into a predetermined distribution;

calibrating the predetermined distribution according to a detected resting heart rate; and

adjusting the predetermined distribution according to additional samples received.

5. The method of claim 4 , wherein adjusting the predetermined distribution according to additional samples received further comprises:

in response to data arriving, multiplying all bins of the predetermined distribution by 1−ε; and

adding ε to a bin corresponding to the data, wherein the ε includes a forgetting parameter for how much the PMF changes with each adaptation run.

6. The method of claim 4 , wherein determining the stress level (SL) using the SF and the PMF further comprises:

adding all bins below a bin corresponding to the SF; and

computing the SL utilizing an algorithm that includes a probability mass function for a given posture (PMF posture ), the SF, and the added bins.

7. The method of claim 6 , further comprising:

adding a fraction of a current bin to improve granularity.

8. The method of claim 1 , further comprising:

tracking both a mean and a standard deviation of a probability distribution as the probability distribution adapts over time; and

combining the mean and the standard deviation to measure long-term stress.

9. The method of claim 1 , wherein the application further causes the processor to:

track both a mean and a standard deviation of a probability distribution as the probability distribution adapts over time; and

combine the mean and the standard deviation to measure long-term stress.

10. A system for measuring psychological stress, the system comprising:

a wireless sensor device coupled to a user via at least one electrode, wherein the wireless sensor device includes a processor; and

a memory device coupled to the processor, wherein the memory device stores an application which, when executed by the processor, causes the processor to:

determine R-R intervals from an electrocardiogram (ECG) to calculate a standard deviation of the R-R intervals (SDNN), wherein the to determine the R-R intervals from the ECG to calculate the SDNN further comprises:

detect R peaks from a measured ECG within a predetermined time period, and

calculate the R-R intervals using the detected R peaks;

determine a stress feature (SF) using the SDNN, wherein the to determine the stress feature (SF) using the SDNN further comprises:

calculate a mean heart rate (HR) from the ECG within the predetermined time period, and

calculate the SF utilizing an algorithm SF=HR+α*SDNN, wherein the α includes a predetermined negative variable that allows for combining the HR and the SDNN;

in response to reaching a threshold, perform adaptation to update a probability mass function (PMF); and

determine a stress level (SL) using the SF and the updated PMF to continuously measure the psychological stress.

11. The system of claim 10 , wherein the application further causes the processor to:

determine a posture state, wherein the psychological stress is not measured if the posture state is active; and

display the determined SL to a user or another device.

12. The system of claim 11 , wherein the posture state includes any of active, sitting, and standing.

13. The system of claim 10 , wherein to perform adaptation to update the PMF further comprises to:

group data into a predetermined distribution;

calibrate the predetermined distribution according to a detected resting heart rate; and

adjust the predetermined distribution according to additional samples received.

14. The system of claim 13 , wherein to adjust the predetermined distribution according to additional samples received further comprises to:

in response to data arriving, multiply all bins of the predetermined distribution by 1−ε; and

add ε to a bin corresponding to the data, wherein the ε includes a forgetting parameter for how much the PMF changes with each adaptation run.

15. The system of claim 13 , wherein to determine the stress level (SL) using the SF and the PMF further comprises to:

add all bins below a bin corresponding to the SF; and

compute the SL utilizing an algorithm that includes a probability mass function for a given posture (PMF posture ), the SF, and the added bins.

16. The system of claim 15 , wherein the application further causes the processor to:

add a fraction of a current bin to improve granularity.

Assignments (7)
RELEASE OF SECURITY INTEREST Recorded Jul 5, 2024
From: INNOVATUS LIFE SCIENCES LENDING FUND I, LP
To: VITAL CONNECT, INC.
Reel/Frame 068146/0132 →
SECURITY INTEREST Recorded Jul 5, 2024
From: VITAL CONNECT, INC.
To: TRINITY CAPITAL INC.
Reel/Frame 068146/0160 →
SECURITY INTEREST Recorded Jan 8, 2021
From: VITAL CONNECT, INC.
To: INNOVATUS LIFE SCIENCES LENDING FUND I, LP
Reel/Frame 054941/0651 →
RELEASE OF SECURITY INTEREST Recorded Jan 8, 2021
From: OXFORD FINANCE LLC
To: VITAL CONNECT, INC.
Reel/Frame 054941/0743 →
SECURITY INTEREST Recorded Apr 9, 2020
From: VITAL CONNECT, INC.
To: OXFORD FINANCE LLC
Reel/Frame 052354/0752 →
RELEASE OF SECURITY INTEREST Recorded Oct 5, 2017
From: PERCEPTIVE CREDIT OPPORTUNITIES FUND, L.P.; PERCEPTIVE CREDIT OPPORTUNITIES GP, LLC
To: VITAL CONNECT, INC.
Reel/Frame 043797/0083 →
PATENT SECURITY AGREEMENT Recorded Jun 10, 2016
From: VITAL CONNECT, INC.
To: PERCEPTIVE CREDIT OPPORTUNITIES FUND, LP; PERCEPTIVE CREDIT OPPORTUNITIES GP, LLC
Reel/Frame 039012/0547 →
Continuity (2)
Continuation 13664199 · Oct 30, 2012
Related Publication 20170020429A1 · Jan 26, 2017