Oral care composition
An oral care composition comprising: (a) arginine, in free or salt form; and (b) zinc oxide and zinc citrate. The oral care composition can reduce or inhibit biofilm formation in an oral cavity.
1. An oral care composition comprising:
a. arginine, in free or salt form; and
b. zinc oxide and zinc citrate,
wherein a molar ratio of arginine to total zinc salts is 0.4:1 to 0.8:1 and wherein a weight ratio of zinc oxide to zinc citrate is 1.7:1 to 2.3:1 and wherein the arginine is present in an amount of 1.4 weight % to 1.6 weight % based on the total weight of the composition.
2. The oral care composition of claim 1 , wherein the arginine is present in an amount of about 1.5 weight %, based on the total weight of the composition.
3. The oral care composition of claim 1 , wherein the total concentration of zinc salts in the composition is 0.2 weight % to 5 weight %, based on the total weight of the composition.
4. The oral care composition of claim 1 , wherein the composition comprises zinc oxide in an amount of 0.5 weight % to 1.5 weight % and zinc citrate in an amount of 0.25 weight % to 0.75 weight %, based on the total weight of the composition.
5. The oral care composition of claim 4 , wherein the composition comprises zinc oxide in an amount of about 1 weight % and zinc citrate in an amount of about 0.5 weight %, based on the total weight of the composition.
6. The oral care composition of claim 4 , wherein the weight ratio of zinc oxide to zinc citrate is 1.9:1 to 2.1:1, or about 2:1.
7. An oral care composition of claim 1 , for use in reducing or inhibiting biofilm formation in an oral cavity.
8. A method of reducing or inhibiting biofilm formation in an oral cavity, the method comprising contacting the oral cavity with an oral care composition of claim 1 .
9. The method of claim 8 , wherein the arginine is present in the oral care composition in an amount of about 1.5 weight %, based on the total weight of the composition.
10. The method of claim 8 , wherein the total concentration of zinc salts in the oral care composition is 0.2 weight % to 5 weight %, based on the total weight of the composition.
11. The method of claim 8 , wherein the zinc oxide is present in the oral care composition in an amount of 0.5 weight % to 1.5 weight % and the zinc citrate is present in the oral care composition in an amount of 0.25 weight % to 0.75 weight %, based on the total weight of the composition.
12. The method of claim 11 , wherein the zinc oxide is present in the oral care composition in an amount of about 1 weight % and the zinc citrate is present in the oral care composition in an amount of about 0.5 weight %, based on the total weight of the composition.
13. The oral care composition of claim 1 , wherein the molar ratio of arginine to total zinc salts is about 0.65:1 and wherein the weight ratio of zinc oxide to zinc citrate is about 2:1.