IP Library Granted Patent US 12,414,728
Granted Patent B2
US 12,414,728 · App. 15/109,488 · Granted Sep 16, 2025

Asystole detection for cardiopulmonary resuscitation

Inventors: Chengzong Han (Andover, MA); Saeed Babaeizadeh (Arlington, MA)
Assignee: Koninklijke Philips N.V.
A61B5/364A61B5/347A61B5/361A61B5/4836A61B5/7207A61B5/7217A61B5/7221A61H31/005A61N1/39044A61N1/3925A61N1/3987
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 12,414,728
App. No.
15/109,488
Granted
Sep 16, 2025
Kind
B2
Abstract

A patient monitoring device ( 20 ) employing an ECG monitor ( 24 ) and a controller ( 26 ). In operation, the ECG monitor ( 24 ) monitors a corrupted ECG waveform ( 30 ), and the controller ( 26 ) classifies the corrupted ECG waveform ( 30 ) as one of a non-shockable rhythm or a potentially shockable rhythm. The corrupted ECG waveform ( 30 ) is classified by the controller ( 26 ) as the non-shockable rhythm responsive to a detection by the controller ( 26 ) of a presence of an asystole rhythm within the corrupted ECG waveform ( 30 ). Conversely, the corrupted ECG waveform ( 30 ) is classified by the controller ( 26 ) as the potentially shockable rhythm responsive to a detection by the controller ( 26 ) of an absence of the asystole rhythm within the corrupted ECG waveform ( 30 ) or an indetermination by the controller ( 26 ) as to the presence of the asystole rhythm within the corrupted ECG waveform ( 30 ).

Claims (47)

1. A patient monitoring device, comprising:

an ECG monitor operable to monitor a corrupted ECG waveform; and

a controller operably connected to the ECG monitor to classify the corrupted ECG waveform as one of a non-shockable asystole rhythm, or a potentially shockable non-asystole rhythm,

wherein the controller is configured to detect a presence or an absence of an asystole rhythm within a segment of the corrupted ECG waveform as indicated by at least one time domain feature and at least one frequency domain feature extracted by the controller from the segment of the corrupted ECG waveform,

wherein the controller is further configured to classify the corrupted ECG waveform as the non-shockable asystole rhythm responsive to a detection by the controller of the presence of the asystole rhythm within the corrupted ECG waveform, and

wherein the controller is further configured to classify the corrupted ECG waveform as the potentially shockable non-asystole rhythm responsive to a detection by the controller of the absence of the asystole rhythm within the corrupted ECG waveform.

2. The patient monitoring device of claim 1 , wherein the controller is further configured to classify the corrupted ECG waveform as the potentially shockable non-asystole rhythm responsive to an indetermination by the controller as to the presence or the absence of the asystole rhythm within the corrupted ECG waveform.

3. The patient monitoring device of claim 1 , wherein the patient monitoring device is at least one of an automatic external defibrillator or an advanced life support defibrillator.

4. The patient monitoring device of claim 1 , wherein the patient monitoring device comprises at least one of an automatic external defibrillator, an advanced life support defibrillator or a patient monitor.

5. The patient monitoring device of claim 1 , wherein the controller includes:

a signal conditioner operably connected to the ECG monitor and configured to condition the segment of the corrupted ECG waveform; and

a feature extractor operably connected to the signal conditioner and configured to extract the at least one time domain feature and the at least one frequency domain feature from the conditioned segment of the corrupted ECG waveform.

6. The patient monitoring device of claim 5 , wherein the signal conditioner removes any artifact from the segment of the ECG waveform.

7. The patient monitoring device of claim 5 , wherein the signal conditioner removes a chest compression artifact from segment of the ECG waveform.

8. The patient monitoring device of claim 5 , wherein the controller further includes a rhythm classifier operably connected to the feature extractor and configured to detect any indication by the at least one time domain feature and the at least one frequency domain feature of the presence of the asystole rhythm within the conditioned segment of the corrupted ECG waveform.

9. The patient monitoring device of claim 5 , wherein the controller further includes a rhythm classifier operably connected to the feature extractor and configured to detect any indication by the at least one time domain feature and the at least one frequency domain feature of the absence of the asystole rhythm within the conditioned segment of the corrupted ECG waveform.

10. The patient monitoring device of claim 5 , wherein the controller further includes a rhythm classifier operably connected to the feature extractor and configured to detect any failure by the at least one time domain feature and the at least one frequency domain feature to indicate one of the presence or the absence of the asystole rhythm within the conditioned segment of the corrupted ECG waveform.

11. The patient monitoring device of claim 1 , wherein the at least frequency domain feature includes an amplitude spectrum area and the at least one time domain feature includes a first difference power of the corrupted ECG waveform.

12. The patient monitoring device of claim 1 , wherein the controller being configured to detect the presence or the absence of the asystole rhythm within the segment of the corrupted ECG waveform as indicated by the at least one frequency domain feature includes the controller configured to:

extract an amplitude spectrum area based frequency variable from the segment of the corrupted ECG waveform; and

compare the amplitude spectrum area based frequency variable to at least one of an asystole detection threshold and a not-asystole detection threshold.

13. The patient monitoring device of claim 1 , wherein the controller being configured to detect the presence or the absence of the asystole rhythm within the segment of the corrupted ECG waveform as indicated by the at least one time domain feature includes the controller configured to:

extract a first difference power based time variable from the segment of the corrupted ECG waveform; and

compare the first difference power based time variable to at least one of an asystole detection threshold and a not-asystole detection threshold.

14. A patient monitoring device controller, comprising:

a feature extractor configured to extract at least one time domain feature and at least one frequency domain feature from a segment of a corrupted ECG waveform,

an asystole advisor operably connected to the feature extractor to classify the corrupted ECG waveform as one of a non-shockable asystole rhythm or a potentially shockable non-asystole rhythm based on an extraction by the feature extractor of the at least one time domain feature and at least one frequency domain feature from the segment of the corrupted ECG waveform,

wherein the asystole advisor is configured to detect a presence or an absence of an asystole rhythm within the segment of the corrupted ECG waveform as indicated by the least one time domain feature and at least one frequency domain feature,

wherein the asystole advisor is further configured to classify the corrupted ECG waveform as the non-shockable asystole rhythm responsive to a detection by the asystole advisor of the presence of the asystole rhythm within the corrupted ECG waveform, and

wherein the asystole advisor is further classified to classify the corrupted ECG waveform as the potentially shockable non-asystole rhythm responsive to a detection by the asystole advisor of the absence of the asystole rhythm within the corrupted ECG waveform; and

a shock advisor operably connected to the asystole advisor to classify the corrupted ECG waveform as either a shockable non-asystole rhythm or a non-shockable non-asystole rhythm responsive to the asystole advisor classifying the corrupted ECG waveform as the potentially shockable non-asystole rhythm.

15. The patient monitoring device controller of claim 14 , wherein the asystole advisor classifies the corrupted ECG waveform as the potentially shockable non-asystole rhythm responsive to an indetermination by the asystole advisor as to the presence or the absence of the asystole rhythm within the corrupted ECG waveform.

16. The patient monitoring device controller of claim 14 , further comprising:

a signal conditioner operable to condition the segment of the corrupted ECG waveform; and

wherein the feature extractor is operably connected to the signal conditioner and configured to extract the at least one time domain feature and at the at least one frequency domain feature from a conditioned segment of the corrupted ECG waveform.

17. The patient monitoring device controller of claim 16 , wherein the asystole advisor includes:

a rhythm classifier operably connected to the feature extractor and configured to:

(i) detect any indication by at least one of the at least one time domain feature and the at least one frequency domain feature of the presence of the asystole rhythm within the conditioned segment of the corrupted ECG waveform,

(ii) detect any indication by the at least one of the at least one time domain feature and the at least one frequency domain feature of the absence of the asystole rhythm within the conditioned segment of the corrupted ECG waveform, and

(iii) detect any failure by the at least one of the at least one time domain feature and the at least one frequency domain feature to indicate one of the presence and the absence of the asystole rhythm within the conditioned segment of the corrupted ECG waveform.

18. The patient monitoring device controller of claim 14 , wherein the at least frequency domain feature includes an amplitude spectrum area and the at least one time domain feature includes a first difference power of the corrupted ECG waveform.

19. The patient monitoring device controller of claim 14 ,

wherein the feature extractor being configured to extract at least one frequency domain feature the segment of the corrupted ECG waveform includes the feature extractor configured to extract an amplitude spectrum area based frequency variable from the segment of the corrupted ECG waveform; and

wherein the asystole advisor being configured to detect the presence or the absence of the asystole rhythm within the segment of the corrupted ECG waveform as indicated by the least one frequency domain feature includes the asystole advisor configured to compare the amplitude spectrum area based frequency variable to at least one of an asystole detection threshold and a not-asystole detection threshold.

20. The patient monitoring device controller of claim 14 ,

wherein the feature extractor being configured to extract at least one time domain feature the segment of the corrupted ECG waveform includes the feature extractor configured to extract a first difference power based time variable from the segment of the corrupted ECG waveform; and

wherein the asystole advisor being configured to detect the presence or the absence of the asystole rhythm within the segment of the corrupted ECG waveform as indicated by the least one time domain feature includes the asystole advisor configured to compare the first difference power based time variable to at least one of an asystole detection threshold and a not-asystole detection threshold.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 3, 2026
From: KONINKLIJKE PHILIPS N.V.
To: EVEREST ACQUISITION ENTITY, LLC
Reel/Frame 075031/0463 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 1, 2016
From: HAN, CHENGZONG; BABAEIZADEH, SAEED
To: KONINKLJKE PHILIPS N.V.
Reel/Frame 039063/0117 →
Continuity (2)
Provisional Application 61922890 · Jan 2, 2014
Related Publication 20160331260A1 · Nov 17, 2016
References Cited (22)
US 5391187A · Freeman · 1995 [cited by examiner]
US 5571142A · Brown · 1996 [cited by examiner]
US 5957856A · Weil et al. · 1999 [cited by applicant]
US 6304773B1 · Taylor · 2001 [cited by examiner]
US 7766828B2 · Ishii et al. · 2010 [cited by applicant]
US 8983588B2 · Addison et al. · 2015 [cited by applicant]
US 9339436B2 · Freeman et al. · 2016 [cited by applicant]
US 9616244B2 · Anderson et al. · 2017 [cited by applicant]
US 9955913B2 · Freeman · 2018 [cited by applicant]
US 20040172068A1 · Sullivan · 2004 [cited by examiner]
US 20060217624A1 · Myklebust · 2006 [cited by examiner]
US 20100114219A1 · Stickney · 2010 [cited by examiner]
US 20110082510A1 · Sullivan · 2011 [cited by applicant]
US 20110202101A1 · Tan et al. · 2011 [cited by applicant]
US 20110224746A1 · Didon · 2011 [cited by applicant]
US 20130296727A1 · Sullivan et al. · 2013 [cited by applicant]
US 20130325515A1 · Nikolova-Simons et al. · 2013 [cited by applicant]
US 20140207012A1 · Coult et al. · 2014 [cited by applicant]
US 20160188824A1 · Geleijnse et al. · 2016 [cited by applicant]
WO 2012176098A1 · 2012 [cited by applicant]
Jette, D.U., et al., “A qualitative study of clinical decision making in recommending discharge placement from teh acute care setting”, Phys Ther. Mar. 2003, 83(3): Abstract. [cited by applicant]
Guidelines focus on minimizing “hands off time”, guidelines and European Resuscitation Council, American Heart Association. [cited by applicant]