IP Library Granted Patent US 10,219,748
Granted Patent B2
US 10,219,748 · App. 15/113,521 · Granted Mar 5, 2019

Gastrointestinal sensor implantation system

Inventors: Benjamin Terry (Lincoln, NE); Weston Lewis (Williamsburg, VA); Wanchuan Xie (Lincoln, NE); Pengbo Li (Lincoln, NE); Alfred Tsubaki (Omaha, NE)
Assignee: NUtech Ventures
A61B5/6861A61B1/273A61B5/073A61B5/6882A61B10/0266A61B10/0283A61B10/04A61B1/041A61B5/4233A61B5/4238A61B5/4255A61B5/6873A61B5/6884A61B5/6885A61B2562/162
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Quick Facts
Patent No.
US 10,219,748
App. No.
15/113,521
Granted
Mar 5, 2019
Kind
B2
Abstract

A gastrointestinal (GI) sensor deployment device is disclosed. In implementations, the sensor deployment device includes an orally-administrable capsule with a tissue capture device removably coupled to the orally-administrable capsule. The tissue capture device includes a plurality of fasteners for connecting the tissue capture device to GI tissue within a body. A biometric sensor is coupled to the tissue capture device for continuous or periodic monitoring of the GI tract of the body at the GI tissue attachment location. A chamber within the orally-administrable capsule is configured to draw gastrointestinal tissue towards the plurality of fasteners when a fluid pressure of the chamber is increased. An actuator can be configured to cause an increase of the fluid pressure of the chamber. Control circuitry coupled to the actuator can be configured to trigger the actuator to cause the increase of the fluid pressure of the chamber at a selected time.

Claims (47)

1. A sensor deployment device, comprising:

an orally-administrable capsule;

a tissue capture device removably coupled to the orally-administrable capsule, the tissue capture device including a plurality of fasteners for connecting the tissue capture device to gastrointestinal tissue within a gastrointestinal tract of a body;

a biometric sensor coupled to the tissue capture device;

a chamber within the orally-administrable capsule, the chamber being configured to draw gastrointestinal tissue towards the plurality of fasteners when a fluid pressure of the chamber is increased;

an actuator configured to cause an increase of the fluid pressure of the chamber; and

control circuitry coupled to the actuator, the control circuitry being configured to trigger the actuator to cause the increase of the fluid pressure of the chamber at a selected time,

wherein the tissue capture device is configured to detach from the orally-administrable capsule, and

wherein the biometric sensor remains coupled to the tissue capture device after the tissue capture device detaches from the orally-administrable capsule.

2. The sensor deployment device of claim 1 , wherein the control circuitry includes a processor in communication with a storage medium, the storage medium bearing program instructions that are executable by the processor.

3. The sensor deployment device of claim 1 , wherein the control circuitry includes a timer circuit.

4. The sensor deployment device of claim 1 , wherein the selected time is based upon a gastrointestinal mapping.

5. The sensor deployment device of claim 4 , wherein the gastrointestinal mapping is derived from pressure data collected by a second orally-administrable capsule at a plurality of times and a plurality of locations within the gastrointestinal tract of the body.

6. The sensor deployment device of claim 1 , further comprising:

a radio frequency (RF) receiver coupled with the control circuitry, wherein the selected time for triggering the actuator is based upon a communication received, via the RF receiver, from a second device located external to the body.

7. The sensor deployment device of claim 1 , further comprising:

a radio frequency (RF) transmitter coupled with the biometric sensor, the RF transmitter being configured to communicate data from the biometric sensor to a second device located external to the body.

8. The sensor deployment device of claim 1 , wherein each fastener of the plurality of fasteners is disposed at an angle ranging between thirty degrees and eighty degrees with respect to an axis that is perpendicular to a top surface of the tissue capture device.

9. A sensor deployment device, comprising:

an orally-administrable capsule;

a tissue capture device removably coupled to the orally-administrable capsule, the tissue capture device including a plurality of fasteners for connecting the tissue capture device to gastrointestinal tissue within a body;

a biometric sensor coupled to the tissue capture device;

a chamber within the orally-administrable capsule, the chamber being configured to draw gastrointestinal tissue towards the plurality of fasteners when a fluid pressure of the chamber is increased;

an actuator configured to cause an increase of the fluid pressure of the chamber; and

control circuitry coupled to the actuator, the control circuitry being configured to trigger the actuator to cause the increase of the fluid pressure of the chamber at a selected time, the selected time being based upon a gastrointestinal mapping derived from pressure data collected by a second orally-administrable capsule at a plurality of times and a plurality of locations within a gastrointestinal tract of the body,

wherein the biometric sensor remains coupled to the tissue capture device after the tissue capture device detaches from the orally-administrable capsule.

10. The sensor deployment device of claim 9 , wherein the control circuitry includes a processor in communication with a storage medium, the storage medium bearing program instructions that are executable by the processor.

11. The sensor deployment device of claim 9 , wherein the control circuitry includes a timer circuit.

12. The sensor deployment device of claim 9 , further comprising:

a radio frequency (RF) transmitter coupled with the biometric sensor, the RF transmitter being configured to communicate data from the biometric sensor to a second device located external to the body.

13. The sensor deployment device of claim 9 , wherein the collected pressure data includes ambient pressure measurements.

14. A sensor deployment method, comprising:

orally administrating a sensor deployment device, the sensor deployment device including:

an orally-administrable capsule;

a tissue capture device removably coupled to the orally-administrable capsule, the tissue capture device including a plurality of fasteners for connecting the tissue capture device to gastrointestinal tissue within a body; and

a biometric sensor coupled to the tissue capture device; and

causing the tissue capture device to, at a selected time, connect to gastrointestinal tissue within a gastrointestinal tract of the body,

wherein the tissue capture device is configured to detach from the orally-administrable capsule, and

wherein the biometric sensor remains coupled to the tissue capture device after the tissue capture device detaches from the orally-administrable capsule.

15. The sensor deployment method of claim 14 , wherein the selected time is based upon a predetermined time interval.

16. The sensor deployment method of claim 15 , wherein the predetermined time interval is based upon a gastrointestinal mapping.

17. The sensor deployment method of claim 16 , wherein the gastrointestinal mapping is derived from pressure data collected by a second orally-administrable capsule at a plurality of times and a plurality of locations within the gastrointestinal tract of the body.

18. The sensor deployment method of claim 14 , further comprising:

receiving data from the biometric sensor with a second device located external to the body.

19. The sensor deployment method of claim 18 , wherein the data received from the biometric sensor includes at least one of a detected pressure, a detected pH, a detected temperature, or a detected attribute of an analyte.

20. The sensor deployment method of claim 14 , wherein causing the tissue capture device to connect to gastrointestinal tissue within the body comprises:

causing fluid to flow into a chamber positioned relative to the tissue capture device such that the gastrointestinal tissue is drawn towards the fasteners of the tissue capture device.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 31, 2017
From: THE BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA
To: NUTECH VENTURES
Reel/Frame 041130/0391 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 18, 2016
From: TERRY, BENJAMIN; LEWIS, WESTON; XIE, WANCHUAN; LI, PENGBO; TSUBAKI, ALFRED
To: THE BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA
Reel/Frame 040365/0662 →
Continuity (2)
Provisional Application 61930219 · Jan 22, 2014
Related Publication 20170027520A1 · Feb 2, 2017
Cited By (2)
US 12,592,310 US 12,697,043